| Full name: alpha-L-fucosidase 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 2517 | HGNC ID: HGNC:4006 | Ensembl Gene: ENSG00000179163 | OMIM ID: 612280 |
| Drug and gene relationship at DGIdb | |||
Expression of FUCA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUCA1 | 2517 | 202838_at | -0.1636 | 0.8254 | |
| GSE20347 | FUCA1 | 2517 | 202838_at | -0.8072 | 0.0004 | |
| GSE23400 | FUCA1 | 2517 | 202838_at | -0.3826 | 0.0000 | |
| GSE26886 | FUCA1 | 2517 | 202838_at | -0.8554 | 0.0095 | |
| GSE29001 | FUCA1 | 2517 | 202838_at | -0.5620 | 0.0609 | |
| GSE38129 | FUCA1 | 2517 | 202838_at | -0.7209 | 0.0001 | |
| GSE45670 | FUCA1 | 2517 | 202838_at | -0.5154 | 0.0520 | |
| GSE53622 | FUCA1 | 2517 | 7385 | -0.3327 | 0.0082 | |
| GSE53624 | FUCA1 | 2517 | 7385 | -0.5618 | 0.0000 | |
| GSE63941 | FUCA1 | 2517 | 202838_at | -0.3218 | 0.8011 | |
| GSE77861 | FUCA1 | 2517 | 202838_at | -0.8853 | 0.0414 | |
| GSE97050 | FUCA1 | 2517 | A_23_P11543 | 0.4733 | 0.1670 | |
| SRP007169 | FUCA1 | 2517 | RNAseq | -0.4748 | 0.3954 | |
| SRP008496 | FUCA1 | 2517 | RNAseq | -0.4719 | 0.1333 | |
| SRP064894 | FUCA1 | 2517 | RNAseq | 0.0181 | 0.9470 | |
| SRP133303 | FUCA1 | 2517 | RNAseq | 0.1156 | 0.6565 | |
| SRP159526 | FUCA1 | 2517 | RNAseq | 0.1923 | 0.6809 | |
| SRP193095 | FUCA1 | 2517 | RNAseq | -0.9332 | 0.0033 | |
| SRP219564 | FUCA1 | 2517 | RNAseq | 0.5967 | 0.1347 | |
| TCGA | FUCA1 | 2517 | RNAseq | -0.4264 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FUCA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FUCA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUCA1 | 2517 | 0 | 5 | 25 | |
| GSE20123 | FUCA1 | 2517 | 0 | 4 | 26 | |
| GSE43470 | FUCA1 | 2517 | 2 | 6 | 35 | |
| GSE46452 | FUCA1 | 2517 | 5 | 1 | 53 | |
| GSE47630 | FUCA1 | 2517 | 8 | 3 | 29 | |
| GSE54993 | FUCA1 | 2517 | 2 | 1 | 67 | |
| GSE54994 | FUCA1 | 2517 | 11 | 4 | 38 | |
| GSE60625 | FUCA1 | 2517 | 0 | 0 | 11 | |
| GSE74703 | FUCA1 | 2517 | 1 | 4 | 31 | |
| GSE74704 | FUCA1 | 2517 | 0 | 0 | 20 | |
| TCGA | FUCA1 | 2517 | 9 | 24 | 63 |
Total number of gains: 38; Total number of losses: 52; Total Number of normals: 398.
Somatic mutations of FUCA1:
Generating mutation plots.
Highly correlated genes for FUCA1:
Showing top 20/1040 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUCA1 | ICK | 0.769554 | 3 | 0 | 3 |
| FUCA1 | EXOC4 | 0.768011 | 3 | 0 | 3 |
| FUCA1 | ZNF35 | 0.762416 | 3 | 0 | 3 |
| FUCA1 | GPD2 | 0.741506 | 3 | 0 | 3 |
| FUCA1 | CCNC | 0.735936 | 3 | 0 | 3 |
| FUCA1 | COPZ1 | 0.733533 | 4 | 0 | 3 |
| FUCA1 | ZNF649 | 0.722152 | 3 | 0 | 3 |
| FUCA1 | PSMD8 | 0.717224 | 3 | 0 | 3 |
| FUCA1 | BTLA | 0.713096 | 3 | 0 | 3 |
| FUCA1 | CLTA | 0.712379 | 3 | 0 | 3 |
| FUCA1 | OGFRL1 | 0.711575 | 6 | 0 | 6 |
| FUCA1 | FBXW5 | 0.710835 | 3 | 0 | 3 |
| FUCA1 | ZACN | 0.710744 | 3 | 0 | 3 |
| FUCA1 | SAMM50 | 0.710728 | 3 | 0 | 3 |
| FUCA1 | NDUFB3 | 0.71067 | 3 | 0 | 3 |
| FUCA1 | HECW2 | 0.708081 | 3 | 0 | 3 |
| FUCA1 | ZNF709 | 0.706528 | 3 | 0 | 3 |
| FUCA1 | C2CD2 | 0.705532 | 4 | 0 | 4 |
| FUCA1 | ZNF829 | 0.697672 | 3 | 0 | 3 |
| FUCA1 | GIMAP5 | 0.694589 | 4 | 0 | 3 |
For details and further investigation, click here
