| Full name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) | Alias Symbol: UDP-GalNAc|A3GALNT|MGC44848|FS | ||
| Type: protein-coding gene | Cytoband: 9q34.2 | ||
| Entrez ID: 26301 | HGNC ID: HGNC:20460 | Ensembl Gene: ENSG00000148288 | OMIM ID: 606074 |
| Drug and gene relationship at DGIdb | |||
Expression of GBGT1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GBGT1 | 26301 | 231780_at | -0.1580 | 0.6623 | |
| GSE26886 | GBGT1 | 26301 | 231780_at | 0.2473 | 0.1673 | |
| GSE45670 | GBGT1 | 26301 | 231780_at | -0.1742 | 0.1787 | |
| GSE53622 | GBGT1 | 26301 | 150715 | -0.0764 | 0.5554 | |
| GSE53624 | GBGT1 | 26301 | 73422 | 0.1750 | 0.0387 | |
| GSE63941 | GBGT1 | 26301 | 231780_at | -1.1581 | 0.0122 | |
| GSE77861 | GBGT1 | 26301 | 231780_at | -0.0061 | 0.9619 | |
| GSE97050 | GBGT1 | 26301 | A_33_P3322373 | 0.3186 | 0.3272 | |
| SRP064894 | GBGT1 | 26301 | RNAseq | 0.4157 | 0.1940 | |
| SRP133303 | GBGT1 | 26301 | RNAseq | -0.5106 | 0.0250 | |
| SRP159526 | GBGT1 | 26301 | RNAseq | 0.8273 | 0.0847 | |
| SRP193095 | GBGT1 | 26301 | RNAseq | 0.2814 | 0.2608 | |
| SRP219564 | GBGT1 | 26301 | RNAseq | 0.3537 | 0.4768 | |
| TCGA | GBGT1 | 26301 | RNAseq | -1.0337 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by GBGT1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GBGT1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GBGT1 | 26301 | 5 | 7 | 18 | |
| GSE20123 | GBGT1 | 26301 | 5 | 7 | 18 | |
| GSE43470 | GBGT1 | 26301 | 4 | 7 | 32 | |
| GSE46452 | GBGT1 | 26301 | 6 | 13 | 40 | |
| GSE47630 | GBGT1 | 26301 | 4 | 15 | 21 | |
| GSE54993 | GBGT1 | 26301 | 3 | 3 | 64 | |
| GSE54994 | GBGT1 | 26301 | 12 | 9 | 32 | |
| GSE60625 | GBGT1 | 26301 | 0 | 0 | 11 | |
| GSE74703 | GBGT1 | 26301 | 4 | 5 | 27 | |
| GSE74704 | GBGT1 | 26301 | 3 | 5 | 12 | |
| TCGA | GBGT1 | 26301 | 28 | 26 | 42 |
Total number of gains: 74; Total number of losses: 97; Total Number of normals: 317.
Somatic mutations of GBGT1:
Generating mutation plots.
Highly correlated genes for GBGT1:
Showing top 20/322 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GBGT1 | RAB37 | 0.798742 | 3 | 0 | 3 |
| GBGT1 | SH3BP5 | 0.790161 | 3 | 0 | 3 |
| GBGT1 | PIP4K2A | 0.782924 | 3 | 0 | 3 |
| GBGT1 | TM7SF3 | 0.772255 | 3 | 0 | 3 |
| GBGT1 | HERPUD1 | 0.763985 | 3 | 0 | 3 |
| GBGT1 | FIG4 | 0.71504 | 3 | 0 | 3 |
| GBGT1 | EIF1AY | 0.714431 | 3 | 0 | 3 |
| GBGT1 | SLITRK6 | 0.7098 | 3 | 0 | 3 |
| GBGT1 | TCN2 | 0.709607 | 5 | 0 | 5 |
| GBGT1 | HPCAL1 | 0.703804 | 3 | 0 | 3 |
| GBGT1 | LRRK2 | 0.703475 | 4 | 0 | 4 |
| GBGT1 | XPC | 0.702785 | 3 | 0 | 3 |
| GBGT1 | DOCK7 | 0.700514 | 3 | 0 | 3 |
| GBGT1 | TMEM176A | 0.699715 | 6 | 0 | 6 |
| GBGT1 | PDE4B | 0.698175 | 4 | 0 | 3 |
| GBGT1 | THSD7A | 0.693932 | 3 | 0 | 3 |
| GBGT1 | CHMP7 | 0.693557 | 4 | 0 | 3 |
| GBGT1 | C19orf38 | 0.693374 | 3 | 0 | 3 |
| GBGT1 | CLEC14A | 0.692134 | 4 | 0 | 4 |
| GBGT1 | THYN1 | 0.691533 | 3 | 0 | 3 |
For details and further investigation, click here
