| Full name: solute carrier family 39 member 6 | Alias Symbol: LIV-1 | ||
| Type: protein-coding gene | Cytoband: 18q12.2 | ||
| Entrez ID: 25800 | HGNC ID: HGNC:18607 | Ensembl Gene: ENSG00000141424 | OMIM ID: 608731 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC39A6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC39A6 | 25800 | 202088_at | 1.2530 | 0.0389 | |
| GSE20347 | SLC39A6 | 25800 | 202088_at | 1.2445 | 0.0000 | |
| GSE23400 | SLC39A6 | 25800 | 202088_at | 1.4513 | 0.0000 | |
| GSE26886 | SLC39A6 | 25800 | 202088_at | 0.3329 | 0.1063 | |
| GSE29001 | SLC39A6 | 25800 | 202088_at | 1.1999 | 0.0013 | |
| GSE38129 | SLC39A6 | 25800 | 202088_at | 1.2509 | 0.0000 | |
| GSE45670 | SLC39A6 | 25800 | 202088_at | 1.1795 | 0.0000 | |
| GSE53622 | SLC39A6 | 25800 | 108006 | 1.2478 | 0.0000 | |
| GSE53624 | SLC39A6 | 25800 | 108006 | 1.3496 | 0.0000 | |
| GSE63941 | SLC39A6 | 25800 | 202088_at | -1.5729 | 0.0069 | |
| GSE77861 | SLC39A6 | 25800 | 202088_at | 1.3708 | 0.0060 | |
| GSE97050 | SLC39A6 | 25800 | A_24_P156049 | 0.6016 | 0.1636 | |
| SRP007169 | SLC39A6 | 25800 | RNAseq | 0.9531 | 0.0061 | |
| SRP008496 | SLC39A6 | 25800 | RNAseq | 1.5383 | 0.0000 | |
| SRP064894 | SLC39A6 | 25800 | RNAseq | 1.4096 | 0.0000 | |
| SRP133303 | SLC39A6 | 25800 | RNAseq | 1.3098 | 0.0000 | |
| SRP159526 | SLC39A6 | 25800 | RNAseq | 1.1502 | 0.0116 | |
| SRP193095 | SLC39A6 | 25800 | RNAseq | 1.2714 | 0.0000 | |
| SRP219564 | SLC39A6 | 25800 | RNAseq | 0.6938 | 0.0717 | |
| TCGA | SLC39A6 | 25800 | RNAseq | 0.3085 | 0.0000 |
Upregulated datasets: 14; Downregulated datasets: 1.
Survival by SLC39A6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC39A6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC39A6 | 25800 | 2 | 5 | 23 | |
| GSE20123 | SLC39A6 | 25800 | 2 | 5 | 23 | |
| GSE43470 | SLC39A6 | 25800 | 0 | 3 | 40 | |
| GSE46452 | SLC39A6 | 25800 | 1 | 25 | 33 | |
| GSE47630 | SLC39A6 | 25800 | 5 | 20 | 15 | |
| GSE54993 | SLC39A6 | 25800 | 8 | 1 | 61 | |
| GSE54994 | SLC39A6 | 25800 | 1 | 16 | 36 | |
| GSE60625 | SLC39A6 | 25800 | 0 | 4 | 7 | |
| GSE74703 | SLC39A6 | 25800 | 0 | 3 | 33 | |
| GSE74704 | SLC39A6 | 25800 | 1 | 4 | 15 | |
| TCGA | SLC39A6 | 25800 | 16 | 39 | 41 |
Total number of gains: 36; Total number of losses: 125; Total Number of normals: 327.
Somatic mutations of SLC39A6:
Generating mutation plots.
Highly correlated genes for SLC39A6:
Showing top 20/1562 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC39A6 | FAM89A | 0.7577 | 3 | 0 | 3 |
| SLC39A6 | TMEM138 | 0.757384 | 7 | 0 | 7 |
| SLC39A6 | ECT2 | 0.753211 | 9 | 0 | 9 |
| SLC39A6 | ALKBH6 | 0.744944 | 3 | 0 | 3 |
| SLC39A6 | C18orf54 | 0.741595 | 6 | 0 | 6 |
| SLC39A6 | CISD2 | 0.732388 | 3 | 0 | 3 |
| SLC39A6 | LRRC34 | 0.723821 | 3 | 0 | 3 |
| SLC39A6 | DPYSL2 | 0.712523 | 5 | 0 | 5 |
| SLC39A6 | UHMK1 | 0.710937 | 6 | 0 | 6 |
| SLC39A6 | NUP107 | 0.707896 | 11 | 0 | 11 |
| SLC39A6 | ARPC1B | 0.705153 | 11 | 0 | 11 |
| SLC39A6 | ZNF622 | 0.702251 | 4 | 0 | 4 |
| SLC39A6 | CDC25B | 0.701646 | 11 | 0 | 11 |
| SLC39A6 | SPON2 | 0.699598 | 3 | 0 | 3 |
| SLC39A6 | ARL13B | 0.699118 | 5 | 0 | 5 |
| SLC39A6 | SLC39A10 | 0.697832 | 5 | 0 | 4 |
| SLC39A6 | HAS3 | 0.697674 | 5 | 0 | 3 |
| SLC39A6 | ATP2C1 | 0.697154 | 11 | 0 | 10 |
| SLC39A6 | DKC1 | 0.695946 | 3 | 0 | 3 |
| SLC39A6 | ALG1 | 0.694308 | 5 | 0 | 4 |
For details and further investigation, click here
