| Full name: oxidative stress induced growth inhibitor 1 | Alias Symbol: BDGI|OKL38 | ||
| Type: protein-coding gene | Cytoband: 16q23.3 | ||
| Entrez ID: 29948 | HGNC ID: HGNC:30093 | Ensembl Gene: ENSG00000140961 | OMIM ID: 607975 |
| Drug and gene relationship at DGIdb | |||
Expression of OSGIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSGIN1 | 29948 | 219475_at | 0.0459 | 0.9486 | |
| GSE20347 | OSGIN1 | 29948 | 219475_at | 0.2776 | 0.0441 | |
| GSE23400 | OSGIN1 | 29948 | 219475_at | 0.2444 | 0.0119 | |
| GSE26886 | OSGIN1 | 29948 | 219475_at | 0.3396 | 0.0473 | |
| GSE29001 | OSGIN1 | 29948 | 219475_at | 0.0655 | 0.7979 | |
| GSE38129 | OSGIN1 | 29948 | 219475_at | 0.3062 | 0.0380 | |
| GSE45670 | OSGIN1 | 29948 | 219475_at | 0.1866 | 0.3392 | |
| GSE53622 | OSGIN1 | 29948 | 8368 | -0.6654 | 0.0055 | |
| GSE53624 | OSGIN1 | 29948 | 8368 | -0.9659 | 0.0000 | |
| GSE63941 | OSGIN1 | 29948 | 219475_at | -0.2218 | 0.6276 | |
| GSE77861 | OSGIN1 | 29948 | 219475_at | 0.2257 | 0.3108 | |
| GSE97050 | OSGIN1 | 29948 | A_23_P77415 | -0.2305 | 0.4373 | |
| SRP007169 | OSGIN1 | 29948 | RNAseq | 1.9490 | 0.0153 | |
| SRP064894 | OSGIN1 | 29948 | RNAseq | -0.0407 | 0.9216 | |
| SRP133303 | OSGIN1 | 29948 | RNAseq | 0.1926 | 0.5238 | |
| SRP159526 | OSGIN1 | 29948 | RNAseq | 2.8930 | 0.0011 | |
| SRP193095 | OSGIN1 | 29948 | RNAseq | 0.9711 | 0.0174 | |
| TCGA | OSGIN1 | 29948 | RNAseq | -0.0049 | 0.9831 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by OSGIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSGIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSGIN1 | 29948 | 5 | 4 | 21 | |
| GSE20123 | OSGIN1 | 29948 | 4 | 4 | 22 | |
| GSE43470 | OSGIN1 | 29948 | 2 | 10 | 31 | |
| GSE46452 | OSGIN1 | 29948 | 37 | 2 | 20 | |
| GSE47630 | OSGIN1 | 29948 | 11 | 9 | 20 | |
| GSE54993 | OSGIN1 | 29948 | 3 | 4 | 63 | |
| GSE54994 | OSGIN1 | 29948 | 8 | 10 | 35 | |
| GSE60625 | OSGIN1 | 29948 | 4 | 0 | 7 | |
| GSE74703 | OSGIN1 | 29948 | 2 | 7 | 27 | |
| GSE74704 | OSGIN1 | 29948 | 3 | 2 | 15 | |
| TCGA | OSGIN1 | 29948 | 25 | 18 | 53 |
Total number of gains: 104; Total number of losses: 70; Total Number of normals: 314.
Somatic mutations of OSGIN1:
Generating mutation plots.
Highly correlated genes for OSGIN1:
Showing top 20/227 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSGIN1 | C19orf53 | 0.732313 | 3 | 0 | 3 |
| OSGIN1 | NHLRC4 | 0.7307 | 3 | 0 | 3 |
| OSGIN1 | MAG | 0.721054 | 3 | 0 | 3 |
| OSGIN1 | CLEC12B | 0.719461 | 3 | 0 | 3 |
| OSGIN1 | PANX2 | 0.701858 | 5 | 0 | 5 |
| OSGIN1 | GPX2 | 0.695538 | 8 | 0 | 8 |
| OSGIN1 | PYY | 0.693099 | 3 | 0 | 3 |
| OSGIN1 | TCTE3 | 0.690029 | 3 | 0 | 3 |
| OSGIN1 | SCN9A | 0.689983 | 9 | 0 | 9 |
| OSGIN1 | KCNA7 | 0.684855 | 3 | 0 | 3 |
| OSGIN1 | UFSP1 | 0.673665 | 3 | 0 | 3 |
| OSGIN1 | GCLM | 0.672561 | 10 | 0 | 9 |
| OSGIN1 | CYP4F11 | 0.672403 | 12 | 0 | 11 |
| OSGIN1 | NOTO | 0.670508 | 3 | 0 | 3 |
| OSGIN1 | CXCR1 | 0.669521 | 3 | 0 | 3 |
| OSGIN1 | GPR62 | 0.666783 | 3 | 0 | 3 |
| OSGIN1 | BARHL2 | 0.662102 | 3 | 0 | 3 |
| OSGIN1 | NME3 | 0.661386 | 3 | 0 | 3 |
| OSGIN1 | ZNF524 | 0.658321 | 3 | 0 | 3 |
| OSGIN1 | HPX | 0.657962 | 4 | 0 | 4 |
For details and further investigation, click here
