| Full name: synaptophysin like 2 | Alias Symbol: Mg29 | ||
| Type: protein-coding gene | Cytoband: 1p13.3 | ||
| Entrez ID: 284612 | HGNC ID: HGNC:27638 | Ensembl Gene: ENSG00000143028 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SYPL2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYPL2 | 284612 | 230611_at | -0.2768 | 0.3468 | |
| GSE26886 | SYPL2 | 284612 | 230611_at | 0.2172 | 0.1360 | |
| GSE45670 | SYPL2 | 284612 | 230611_at | -0.2060 | 0.0085 | |
| GSE53622 | SYPL2 | 284612 | 36737 | -0.0492 | 0.6428 | |
| GSE53624 | SYPL2 | 284612 | 36737 | -0.1896 | 0.0344 | |
| GSE63941 | SYPL2 | 284612 | 230611_at | -1.3885 | 0.0005 | |
| GSE77861 | SYPL2 | 284612 | 230611_at | 0.1123 | 0.4869 | |
| GSE97050 | SYPL2 | 284612 | A_33_P3376095 | -0.4353 | 0.2911 | |
| SRP064894 | SYPL2 | 284612 | RNAseq | -0.1612 | 0.6890 | |
| SRP133303 | SYPL2 | 284612 | RNAseq | -1.3712 | 0.0000 | |
| SRP159526 | SYPL2 | 284612 | RNAseq | -0.3338 | 0.6599 | |
| SRP219564 | SYPL2 | 284612 | RNAseq | 0.1055 | 0.9074 | |
| TCGA | SYPL2 | 284612 | RNAseq | -1.6280 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SYPL2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYPL2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYPL2 | 284612 | 0 | 12 | 18 | |
| GSE20123 | SYPL2 | 284612 | 0 | 11 | 19 | |
| GSE43470 | SYPL2 | 284612 | 0 | 8 | 35 | |
| GSE46452 | SYPL2 | 284612 | 2 | 1 | 56 | |
| GSE47630 | SYPL2 | 284612 | 9 | 5 | 26 | |
| GSE54993 | SYPL2 | 284612 | 0 | 1 | 69 | |
| GSE54994 | SYPL2 | 284612 | 7 | 4 | 42 | |
| GSE60625 | SYPL2 | 284612 | 0 | 0 | 11 | |
| GSE74703 | SYPL2 | 284612 | 0 | 6 | 30 | |
| GSE74704 | SYPL2 | 284612 | 0 | 7 | 13 | |
| TCGA | SYPL2 | 284612 | 8 | 26 | 62 |
Total number of gains: 26; Total number of losses: 81; Total Number of normals: 381.
Somatic mutations of SYPL2:
Generating mutation plots.
Highly correlated genes for SYPL2:
Showing top 20/219 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYPL2 | CARNS1 | 0.791746 | 3 | 0 | 3 |
| SYPL2 | PGPEP1 | 0.76075 | 3 | 0 | 3 |
| SYPL2 | SPTBN4 | 0.748607 | 3 | 0 | 3 |
| SYPL2 | FGF14 | 0.745312 | 3 | 0 | 3 |
| SYPL2 | TSHB | 0.743329 | 3 | 0 | 3 |
| SYPL2 | MAGEE2 | 0.728594 | 3 | 0 | 3 |
| SYPL2 | HCRTR1 | 0.72767 | 3 | 0 | 3 |
| SYPL2 | HRCT1 | 0.716179 | 3 | 0 | 3 |
| SYPL2 | ARL8A | 0.714646 | 3 | 0 | 3 |
| SYPL2 | SLC7A14 | 0.712082 | 3 | 0 | 3 |
| SYPL2 | C3orf56 | 0.707293 | 3 | 0 | 3 |
| SYPL2 | CHRNA2 | 0.706578 | 3 | 0 | 3 |
| SYPL2 | TCTE3 | 0.705253 | 3 | 0 | 3 |
| SYPL2 | SIGIRR | 0.70525 | 4 | 0 | 4 |
| SYPL2 | ABTB1 | 0.704955 | 3 | 0 | 3 |
| SYPL2 | DPP6 | 0.702943 | 5 | 0 | 4 |
| SYPL2 | NXPH3 | 0.702208 | 4 | 0 | 3 |
| SYPL2 | CNTN4 | 0.699841 | 4 | 0 | 4 |
| SYPL2 | ZCWPW1 | 0.698417 | 3 | 0 | 3 |
| SYPL2 | BTBD9 | 0.696944 | 3 | 0 | 3 |
For details and further investigation, click here
