| Full name: peripherin 2 | Alias Symbol: TSPAN22|rd2|CACD2 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 5961 | HGNC ID: HGNC:9942 | Ensembl Gene: ENSG00000112619 | OMIM ID: 179605 |
| Drug and gene relationship at DGIdb | |||
Expression of PRPH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PRPH2 | 5961 | 206625_at | -0.4511 | 0.1517 | |
| GSE20347 | PRPH2 | 5961 | 206625_at | -0.0785 | 0.4178 | |
| GSE23400 | PRPH2 | 5961 | 206625_at | -0.2168 | 0.0000 | |
| GSE26886 | PRPH2 | 5961 | 206625_at | 0.0021 | 0.9874 | |
| GSE29001 | PRPH2 | 5961 | 206625_at | -0.2922 | 0.0588 | |
| GSE38129 | PRPH2 | 5961 | 206625_at | -0.3052 | 0.0001 | |
| GSE45670 | PRPH2 | 5961 | 206625_at | -0.3322 | 0.0017 | |
| GSE53622 | PRPH2 | 5961 | 37347 | -0.2058 | 0.2788 | |
| GSE53624 | PRPH2 | 5961 | 37347 | 0.1355 | 0.4412 | |
| GSE63941 | PRPH2 | 5961 | 206625_at | -2.0364 | 0.0000 | |
| GSE77861 | PRPH2 | 5961 | 206625_at | -0.0578 | 0.6690 | |
| GSE97050 | PRPH2 | 5961 | A_23_P214459 | 0.0378 | 0.8726 | |
| SRP064894 | PRPH2 | 5961 | RNAseq | 0.2325 | 0.5567 | |
| SRP133303 | PRPH2 | 5961 | RNAseq | -0.1731 | 0.5512 | |
| SRP159526 | PRPH2 | 5961 | RNAseq | -0.7791 | 0.1174 | |
| SRP193095 | PRPH2 | 5961 | RNAseq | 0.3881 | 0.0496 | |
| SRP219564 | PRPH2 | 5961 | RNAseq | 0.3432 | 0.5804 | |
| TCGA | PRPH2 | 5961 | RNAseq | -0.9498 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by PRPH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PRPH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PRPH2 | 5961 | 7 | 0 | 23 | |
| GSE20123 | PRPH2 | 5961 | 7 | 0 | 23 | |
| GSE43470 | PRPH2 | 5961 | 6 | 0 | 37 | |
| GSE46452 | PRPH2 | 5961 | 2 | 9 | 48 | |
| GSE47630 | PRPH2 | 5961 | 8 | 4 | 28 | |
| GSE54993 | PRPH2 | 5961 | 3 | 2 | 65 | |
| GSE54994 | PRPH2 | 5961 | 11 | 4 | 38 | |
| GSE60625 | PRPH2 | 5961 | 0 | 1 | 10 | |
| GSE74703 | PRPH2 | 5961 | 6 | 0 | 30 | |
| GSE74704 | PRPH2 | 5961 | 3 | 0 | 17 | |
| TCGA | PRPH2 | 5961 | 20 | 14 | 62 |
Total number of gains: 73; Total number of losses: 34; Total Number of normals: 381.
Somatic mutations of PRPH2:
Generating mutation plots.
Highly correlated genes for PRPH2:
Showing top 20/1027 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PRPH2 | C10orf82 | 0.786487 | 3 | 0 | 3 |
| PRPH2 | IL33 | 0.76802 | 4 | 0 | 4 |
| PRPH2 | BRINP2 | 0.759423 | 3 | 0 | 3 |
| PRPH2 | TMEM140 | 0.753056 | 3 | 0 | 3 |
| PRPH2 | RAB23 | 0.751508 | 3 | 0 | 3 |
| PRPH2 | LIPF | 0.750218 | 3 | 0 | 3 |
| PRPH2 | TNFSF4 | 0.749218 | 3 | 0 | 3 |
| PRPH2 | MAML2 | 0.743723 | 4 | 0 | 4 |
| PRPH2 | STXBP4 | 0.740431 | 3 | 0 | 3 |
| PRPH2 | JAK2 | 0.739992 | 3 | 0 | 3 |
| PRPH2 | OCM2 | 0.738626 | 4 | 0 | 4 |
| PRPH2 | FIBIN | 0.737194 | 4 | 0 | 4 |
| PRPH2 | LRRK2 | 0.736183 | 4 | 0 | 4 |
| PRPH2 | LINC01279 | 0.733388 | 3 | 0 | 3 |
| PRPH2 | CYP4V2 | 0.723288 | 4 | 0 | 4 |
| PRPH2 | ST3GAL5 | 0.722561 | 3 | 0 | 3 |
| PRPH2 | CD63 | 0.716551 | 4 | 0 | 3 |
| PRPH2 | ARHGAP31 | 0.713364 | 6 | 0 | 6 |
| PRPH2 | IGFBP5 | 0.709766 | 4 | 0 | 3 |
| PRPH2 | LBX1 | 0.709063 | 4 | 0 | 4 |
For details and further investigation, click here
