| Full name: tetratricopeptide repeat domain 7B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q32.11 | ||
| Entrez ID: 145567 | HGNC ID: HGNC:19858 | Ensembl Gene: ENSG00000165914 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTC7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTC7B | 145567 | 226152_at | 0.4958 | 0.6133 | |
| GSE26886 | TTC7B | 145567 | 226152_at | 2.2629 | 0.0000 | |
| GSE45670 | TTC7B | 145567 | 226152_at | 0.1929 | 0.6269 | |
| GSE53622 | TTC7B | 145567 | 34576 | 0.4893 | 0.0007 | |
| GSE53624 | TTC7B | 145567 | 34576 | 0.9256 | 0.0000 | |
| GSE63941 | TTC7B | 145567 | 226152_at | -0.4371 | 0.7047 | |
| GSE77861 | TTC7B | 145567 | 226152_at | 1.5945 | 0.0137 | |
| GSE97050 | TTC7B | 145567 | A_23_P25974 | -0.3521 | 0.4228 | |
| SRP007169 | TTC7B | 145567 | RNAseq | 2.1418 | 0.0003 | |
| SRP008496 | TTC7B | 145567 | RNAseq | 2.2033 | 0.0000 | |
| SRP064894 | TTC7B | 145567 | RNAseq | 0.6121 | 0.0001 | |
| SRP133303 | TTC7B | 145567 | RNAseq | 0.6325 | 0.0014 | |
| SRP159526 | TTC7B | 145567 | RNAseq | 1.1072 | 0.0023 | |
| SRP193095 | TTC7B | 145567 | RNAseq | 1.1878 | 0.0000 | |
| SRP219564 | TTC7B | 145567 | RNAseq | -0.0441 | 0.9542 | |
| TCGA | TTC7B | 145567 | RNAseq | -0.1376 | 0.0966 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by TTC7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTC7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTC7B | 145567 | 9 | 5 | 16 | |
| GSE20123 | TTC7B | 145567 | 9 | 5 | 16 | |
| GSE43470 | TTC7B | 145567 | 7 | 3 | 33 | |
| GSE46452 | TTC7B | 145567 | 16 | 3 | 40 | |
| GSE47630 | TTC7B | 145567 | 11 | 8 | 21 | |
| GSE54993 | TTC7B | 145567 | 3 | 8 | 59 | |
| GSE54994 | TTC7B | 145567 | 19 | 4 | 30 | |
| GSE60625 | TTC7B | 145567 | 0 | 2 | 9 | |
| GSE74703 | TTC7B | 145567 | 6 | 3 | 27 | |
| GSE74704 | TTC7B | 145567 | 4 | 4 | 12 | |
| TCGA | TTC7B | 145567 | 30 | 21 | 45 |
Total number of gains: 114; Total number of losses: 66; Total Number of normals: 308.
Somatic mutations of TTC7B:
Generating mutation plots.
Highly correlated genes for TTC7B:
Showing top 20/1493 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTC7B | TIGD1 | 0.837472 | 3 | 0 | 3 |
| TTC7B | CPT1A | 0.814349 | 3 | 0 | 3 |
| TTC7B | ZHX2 | 0.800708 | 3 | 0 | 3 |
| TTC7B | C20orf194 | 0.798121 | 4 | 0 | 4 |
| TTC7B | INTS3 | 0.794822 | 3 | 0 | 3 |
| TTC7B | RAB23 | 0.793187 | 5 | 0 | 5 |
| TTC7B | WDR81 | 0.787246 | 3 | 0 | 3 |
| TTC7B | PSMD3 | 0.7819 | 3 | 0 | 3 |
| TTC7B | ZBED1 | 0.769522 | 3 | 0 | 3 |
| TTC7B | SLC39A13 | 0.758517 | 7 | 0 | 6 |
| TTC7B | FBXO31 | 0.757239 | 3 | 0 | 3 |
| TTC7B | C1orf216 | 0.757155 | 7 | 0 | 7 |
| TTC7B | RHOBTB1 | 0.757135 | 7 | 0 | 7 |
| TTC7B | SHANK3 | 0.756235 | 3 | 0 | 3 |
| TTC7B | RNF115 | 0.754073 | 4 | 0 | 4 |
| TTC7B | RILPL1 | 0.753784 | 5 | 0 | 5 |
| TTC7B | TSPYL2 | 0.752147 | 3 | 0 | 3 |
| TTC7B | SSBP4 | 0.750228 | 4 | 0 | 3 |
| TTC7B | LAMC1 | 0.748325 | 7 | 0 | 7 |
| TTC7B | MGP | 0.748216 | 3 | 0 | 3 |
For details and further investigation, click here
