| Full name: anoctamin 6 | Alias Symbol: DKFZp313M0720 | ||
| Type: protein-coding gene | Cytoband: 12q12 | ||
| Entrez ID: 196527 | HGNC ID: HGNC:25240 | Ensembl Gene: ENSG00000177119 | OMIM ID: 608663 |
| Drug and gene relationship at DGIdb | |||
Expression of ANO6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ANO6 | 196527 | 224906_at | -0.4487 | 0.4429 | |
| GSE26886 | ANO6 | 196527 | 224906_at | 0.9797 | 0.0002 | |
| GSE45670 | ANO6 | 196527 | 224906_at | -0.3988 | 0.1383 | |
| GSE53622 | ANO6 | 196527 | 64135 | 0.1066 | 0.3126 | |
| GSE53624 | ANO6 | 196527 | 64135 | 0.3546 | 0.0000 | |
| GSE63941 | ANO6 | 196527 | 224906_at | -0.9609 | 0.0152 | |
| GSE77861 | ANO6 | 196527 | 224906_at | 1.0453 | 0.0607 | |
| GSE97050 | ANO6 | 196527 | A_23_P389118 | -0.3988 | 0.2332 | |
| SRP007169 | ANO6 | 196527 | RNAseq | 1.2936 | 0.0018 | |
| SRP008496 | ANO6 | 196527 | RNAseq | 1.2989 | 0.0000 | |
| SRP064894 | ANO6 | 196527 | RNAseq | 0.1851 | 0.4603 | |
| SRP133303 | ANO6 | 196527 | RNAseq | 0.6253 | 0.0022 | |
| SRP159526 | ANO6 | 196527 | RNAseq | -0.1217 | 0.7142 | |
| SRP193095 | ANO6 | 196527 | RNAseq | 0.9250 | 0.0000 | |
| SRP219564 | ANO6 | 196527 | RNAseq | -0.2215 | 0.7178 | |
| TCGA | ANO6 | 196527 | RNAseq | -0.0591 | 0.3480 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ANO6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ANO6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ANO6 | 196527 | 6 | 1 | 23 | |
| GSE20123 | ANO6 | 196527 | 6 | 1 | 23 | |
| GSE43470 | ANO6 | 196527 | 3 | 1 | 39 | |
| GSE46452 | ANO6 | 196527 | 8 | 1 | 50 | |
| GSE47630 | ANO6 | 196527 | 11 | 2 | 27 | |
| GSE54993 | ANO6 | 196527 | 0 | 6 | 64 | |
| GSE54994 | ANO6 | 196527 | 7 | 1 | 45 | |
| GSE60625 | ANO6 | 196527 | 0 | 0 | 11 | |
| GSE74703 | ANO6 | 196527 | 3 | 1 | 32 | |
| GSE74704 | ANO6 | 196527 | 3 | 1 | 16 | |
| TCGA | ANO6 | 196527 | 16 | 14 | 66 |
Total number of gains: 63; Total number of losses: 29; Total Number of normals: 396.
Somatic mutations of ANO6:
Generating mutation plots.
Highly correlated genes for ANO6:
Showing top 20/1064 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ANO6 | FOXN3 | 0.860046 | 3 | 0 | 3 |
| ANO6 | NBR1 | 0.809 | 3 | 0 | 3 |
| ANO6 | ALPK3 | 0.799234 | 3 | 0 | 3 |
| ANO6 | CLMP | 0.795517 | 6 | 0 | 6 |
| ANO6 | PDK3 | 0.788087 | 3 | 0 | 3 |
| ANO6 | RAB23 | 0.781372 | 6 | 0 | 6 |
| ANO6 | KIF5C | 0.779571 | 3 | 0 | 3 |
| ANO6 | ST13 | 0.774178 | 3 | 0 | 3 |
| ANO6 | EFEMP2 | 0.762998 | 8 | 0 | 8 |
| ANO6 | MCAM | 0.762669 | 6 | 0 | 6 |
| ANO6 | SYNC | 0.760795 | 4 | 0 | 4 |
| ANO6 | STK17A | 0.759908 | 3 | 0 | 3 |
| ANO6 | AP1S2 | 0.759116 | 4 | 0 | 4 |
| ANO6 | ZSWIM5 | 0.751792 | 3 | 0 | 3 |
| ANO6 | EIF3L | 0.750623 | 3 | 0 | 3 |
| ANO6 | CLIC4 | 0.748898 | 9 | 0 | 9 |
| ANO6 | NCOR2 | 0.748787 | 3 | 0 | 3 |
| ANO6 | BAG2 | 0.746767 | 7 | 0 | 7 |
| ANO6 | ZNF558 | 0.737585 | 3 | 0 | 3 |
| ANO6 | JMY | 0.735881 | 4 | 0 | 3 |
For details and further investigation, click here
