| Full name: ankyrin repeat and SOCS box containing 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 140460 | HGNC ID: HGNC:17182 | Ensembl Gene: ENSG00000183475 | OMIM ID: 615052 |
| Drug and gene relationship at DGIdb | |||
Expression of ASB7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASB7 | 140460 | 226513_at | 0.3734 | 0.5219 | |
| GSE20347 | ASB7 | 140460 | 219996_at | -0.0009 | 0.9918 | |
| GSE23400 | ASB7 | 140460 | 219996_at | -0.0295 | 0.4936 | |
| GSE26886 | ASB7 | 140460 | 226513_at | 1.0279 | 0.0000 | |
| GSE29001 | ASB7 | 140460 | 219996_at | -0.0797 | 0.6485 | |
| GSE38129 | ASB7 | 140460 | 219996_at | 0.0622 | 0.4912 | |
| GSE45670 | ASB7 | 140460 | 226513_at | 0.1004 | 0.4482 | |
| GSE53622 | ASB7 | 140460 | 45527 | 0.1436 | 0.0287 | |
| GSE53624 | ASB7 | 140460 | 45527 | 0.2662 | 0.0000 | |
| GSE63941 | ASB7 | 140460 | 226513_at | -0.2951 | 0.3782 | |
| GSE77861 | ASB7 | 140460 | 219996_at | 0.1056 | 0.4033 | |
| GSE97050 | ASB7 | 140460 | A_24_P155791 | -0.0353 | 0.8905 | |
| SRP007169 | ASB7 | 140460 | RNAseq | 0.6404 | 0.1402 | |
| SRP008496 | ASB7 | 140460 | RNAseq | 1.0117 | 0.0113 | |
| SRP064894 | ASB7 | 140460 | RNAseq | 0.0796 | 0.5825 | |
| SRP133303 | ASB7 | 140460 | RNAseq | 0.2543 | 0.1218 | |
| SRP159526 | ASB7 | 140460 | RNAseq | 0.1825 | 0.3016 | |
| SRP193095 | ASB7 | 140460 | RNAseq | 0.2898 | 0.0012 | |
| SRP219564 | ASB7 | 140460 | RNAseq | -0.0825 | 0.8408 | |
| TCGA | ASB7 | 140460 | RNAseq | 0.0635 | 0.2473 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ASB7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASB7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASB7 | 140460 | 7 | 2 | 21 | |
| GSE20123 | ASB7 | 140460 | 7 | 2 | 21 | |
| GSE43470 | ASB7 | 140460 | 6 | 5 | 32 | |
| GSE46452 | ASB7 | 140460 | 3 | 7 | 49 | |
| GSE47630 | ASB7 | 140460 | 9 | 10 | 21 | |
| GSE54993 | ASB7 | 140460 | 4 | 7 | 59 | |
| GSE54994 | ASB7 | 140460 | 8 | 7 | 38 | |
| GSE60625 | ASB7 | 140460 | 4 | 0 | 7 | |
| GSE74703 | ASB7 | 140460 | 5 | 4 | 27 | |
| GSE74704 | ASB7 | 140460 | 3 | 3 | 14 | |
| TCGA | ASB7 | 140460 | 18 | 12 | 66 |
Total number of gains: 74; Total number of losses: 59; Total Number of normals: 355.
Somatic mutations of ASB7:
Generating mutation plots.
Highly correlated genes for ASB7:
Showing top 20/502 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASB7 | TADA3 | 0.806678 | 3 | 0 | 3 |
| ASB7 | DENND1A | 0.80069 | 3 | 0 | 3 |
| ASB7 | FAM111B | 0.798044 | 3 | 0 | 3 |
| ASB7 | RAB23 | 0.780542 | 3 | 0 | 3 |
| ASB7 | SFT2D3 | 0.776225 | 4 | 0 | 4 |
| ASB7 | PSMA5 | 0.773878 | 3 | 0 | 3 |
| ASB7 | APP | 0.773591 | 3 | 0 | 3 |
| ASB7 | RP9 | 0.77111 | 3 | 0 | 3 |
| ASB7 | SPEN | 0.764023 | 3 | 0 | 3 |
| ASB7 | SEMA3C | 0.757674 | 3 | 0 | 3 |
| ASB7 | FADD | 0.747958 | 3 | 0 | 3 |
| ASB7 | CHCHD6 | 0.747171 | 3 | 0 | 3 |
| ASB7 | EID2 | 0.745885 | 3 | 0 | 3 |
| ASB7 | FAM171B | 0.743234 | 4 | 0 | 3 |
| ASB7 | PET117 | 0.740946 | 3 | 0 | 3 |
| ASB7 | ACP1 | 0.740147 | 3 | 0 | 3 |
| ASB7 | C9orf78 | 0.739469 | 3 | 0 | 3 |
| ASB7 | GSR | 0.729933 | 4 | 0 | 4 |
| ASB7 | CPT1A | 0.728159 | 4 | 0 | 4 |
| ASB7 | TRIM37 | 0.727494 | 3 | 0 | 3 |
For details and further investigation, click here
