| Full name: zymogen granule protein 16 | Alias Symbol: hZG16|JCLN1|ZG16A | ||
| Type: protein-coding gene | Cytoband: 16p11.2 | ||
| Entrez ID: 653808 | HGNC ID: HGNC:30961 | Ensembl Gene: ENSG00000174992 | OMIM ID: 617311 |
| Drug and gene relationship at DGIdb | |||
Expression of ZG16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZG16 | 653808 | 214142_at | -0.0855 | 0.7222 | |
| GSE20347 | ZG16 | 653808 | 214142_at | -0.0763 | 0.2978 | |
| GSE23400 | ZG16 | 653808 | 214142_at | -0.1410 | 0.0003 | |
| GSE26886 | ZG16 | 653808 | 214142_at | -0.0719 | 0.6139 | |
| GSE29001 | ZG16 | 653808 | 214142_at | -0.2651 | 0.1102 | |
| GSE38129 | ZG16 | 653808 | 214142_at | -0.1084 | 0.0898 | |
| GSE45670 | ZG16 | 653808 | 214142_at | -0.1061 | 0.2166 | |
| GSE53622 | ZG16 | 653808 | 114013 | 0.0078 | 0.9555 | |
| GSE53624 | ZG16 | 653808 | 114013 | 0.0614 | 0.6401 | |
| GSE63941 | ZG16 | 653808 | 214142_at | 0.4287 | 0.1590 | |
| GSE77861 | ZG16 | 653808 | 214142_at | -0.1750 | 0.2745 | |
| SRP133303 | ZG16 | 653808 | RNAseq | 0.0283 | 0.9075 | |
| SRP193095 | ZG16 | 653808 | RNAseq | -0.9039 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZG16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZG16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZG16 | 653808 | 5 | 5 | 20 | |
| GSE20123 | ZG16 | 653808 | 5 | 4 | 21 | |
| GSE43470 | ZG16 | 653808 | 3 | 3 | 37 | |
| GSE46452 | ZG16 | 653808 | 38 | 1 | 20 | |
| GSE47630 | ZG16 | 653808 | 11 | 7 | 22 | |
| GSE54993 | ZG16 | 653808 | 3 | 5 | 62 | |
| GSE54994 | ZG16 | 653808 | 5 | 9 | 39 | |
| GSE60625 | ZG16 | 653808 | 4 | 0 | 7 | |
| GSE74703 | ZG16 | 653808 | 3 | 2 | 31 | |
| GSE74704 | ZG16 | 653808 | 3 | 2 | 15 | |
| TCGA | ZG16 | 653808 | 20 | 11 | 65 |
Total number of gains: 100; Total number of losses: 49; Total Number of normals: 339.
Somatic mutations of ZG16:
Generating mutation plots.
Highly correlated genes for ZG16:
Showing top 20/465 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZG16 | OR1J4 | 0.760421 | 3 | 0 | 3 |
| ZG16 | ZMYND10 | 0.728522 | 3 | 0 | 3 |
| ZG16 | KIF25 | 0.719784 | 3 | 0 | 3 |
| ZG16 | SPACA4 | 0.711916 | 3 | 0 | 3 |
| ZG16 | MPL | 0.707362 | 4 | 0 | 4 |
| ZG16 | LIPF | 0.704349 | 3 | 0 | 3 |
| ZG16 | GPSM3 | 0.700184 | 3 | 0 | 3 |
| ZG16 | CABP1 | 0.698921 | 3 | 0 | 3 |
| ZG16 | PKDREJ | 0.687006 | 3 | 0 | 3 |
| ZG16 | VCX2 | 0.686686 | 3 | 0 | 3 |
| ZG16 | SLC2A4 | 0.685313 | 3 | 0 | 3 |
| ZG16 | SLC25A47 | 0.671507 | 3 | 0 | 3 |
| ZG16 | TLX1 | 0.658535 | 4 | 0 | 3 |
| ZG16 | RDH8 | 0.656855 | 4 | 0 | 4 |
| ZG16 | GDF5 | 0.654784 | 3 | 0 | 3 |
| ZG16 | IQSEC3 | 0.653374 | 3 | 0 | 3 |
| ZG16 | AMBRA1 | 0.651158 | 3 | 0 | 3 |
| ZG16 | SPIN2A | 0.650373 | 6 | 0 | 4 |
| ZG16 | GPR37L1 | 0.649258 | 5 | 0 | 4 |
| ZG16 | LIPC | 0.648751 | 3 | 0 | 3 |
For details and further investigation, click here
