| Full name: regulatory factor X3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p24.2 | ||
| Entrez ID: 5991 | HGNC ID: HGNC:9984 | Ensembl Gene: ENSG00000080298 | OMIM ID: 601337 |
| Drug and gene relationship at DGIdb | |||
Expression of RFX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RFX3 | 5991 | 230403_at | -0.1543 | 0.8536 | |
| GSE20347 | RFX3 | 5991 | 207234_at | -0.0223 | 0.7300 | |
| GSE23400 | RFX3 | 5991 | 207234_at | -0.0191 | 0.3312 | |
| GSE26886 | RFX3 | 5991 | 230403_at | 0.2629 | 0.3497 | |
| GSE29001 | RFX3 | 5991 | 207234_at | 0.0486 | 0.6976 | |
| GSE38129 | RFX3 | 5991 | 207234_at | -0.0351 | 0.5131 | |
| GSE45670 | RFX3 | 5991 | 230403_at | -0.7612 | 0.0349 | |
| GSE53622 | RFX3 | 5991 | 89656 | 0.2231 | 0.0355 | |
| GSE53624 | RFX3 | 5991 | 89656 | 0.2076 | 0.0868 | |
| GSE63941 | RFX3 | 5991 | 243868_at | 0.1151 | 0.8122 | |
| GSE77861 | RFX3 | 5991 | 243868_at | -0.0797 | 0.4450 | |
| GSE97050 | RFX3 | 5991 | A_23_P9289 | 0.4381 | 0.1399 | |
| SRP007169 | RFX3 | 5991 | RNAseq | 0.2903 | 0.6674 | |
| SRP008496 | RFX3 | 5991 | RNAseq | 0.4119 | 0.3806 | |
| SRP064894 | RFX3 | 5991 | RNAseq | -0.0041 | 0.9868 | |
| SRP133303 | RFX3 | 5991 | RNAseq | -0.1865 | 0.3917 | |
| SRP159526 | RFX3 | 5991 | RNAseq | -0.5822 | 0.0676 | |
| SRP193095 | RFX3 | 5991 | RNAseq | -0.0942 | 0.6485 | |
| SRP219564 | RFX3 | 5991 | RNAseq | -0.0955 | 0.8319 | |
| TCGA | RFX3 | 5991 | RNAseq | -0.1810 | 0.2538 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RFX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RFX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RFX3 | 5991 | 1 | 16 | 13 | |
| GSE20123 | RFX3 | 5991 | 1 | 15 | 14 | |
| GSE43470 | RFX3 | 5991 | 4 | 13 | 26 | |
| GSE46452 | RFX3 | 5991 | 2 | 23 | 34 | |
| GSE47630 | RFX3 | 5991 | 4 | 27 | 9 | |
| GSE54993 | RFX3 | 5991 | 6 | 3 | 61 | |
| GSE54994 | RFX3 | 5991 | 9 | 18 | 26 | |
| GSE60625 | RFX3 | 5991 | 0 | 2 | 9 | |
| GSE74703 | RFX3 | 5991 | 4 | 10 | 22 | |
| GSE74704 | RFX3 | 5991 | 0 | 12 | 8 | |
| TCGA | RFX3 | 5991 | 13 | 53 | 30 |
Total number of gains: 44; Total number of losses: 192; Total Number of normals: 252.
Somatic mutations of RFX3:
Generating mutation plots.
Highly correlated genes for RFX3:
Showing top 20/83 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RFX3 | S1PR2 | 0.730659 | 3 | 0 | 3 |
| RFX3 | MLLT3 | 0.662491 | 3 | 0 | 3 |
| RFX3 | OR7E24 | 0.647685 | 4 | 0 | 4 |
| RFX3 | MARK4 | 0.63881 | 3 | 0 | 3 |
| RFX3 | CNOT6L | 0.638655 | 3 | 0 | 3 |
| RFX3 | SOX5 | 0.637442 | 3 | 0 | 3 |
| RFX3 | TAS2R30 | 0.634613 | 3 | 0 | 3 |
| RFX3 | RNF165 | 0.630062 | 3 | 0 | 3 |
| RFX3 | CCDC106 | 0.626402 | 3 | 0 | 3 |
| RFX3 | CASC2 | 0.62541 | 5 | 0 | 4 |
| RFX3 | USP54 | 0.62375 | 3 | 0 | 3 |
| RFX3 | IFNW1 | 0.617316 | 4 | 0 | 3 |
| RFX3 | ANKRD44 | 0.61568 | 4 | 0 | 4 |
| RFX3 | HEYL | 0.615136 | 3 | 0 | 3 |
| RFX3 | LETMD1 | 0.613505 | 3 | 0 | 3 |
| RFX3 | GFRA1 | 0.611187 | 4 | 0 | 3 |
| RFX3 | PACRGL | 0.61071 | 5 | 0 | 5 |
| RFX3 | CHRDL1 | 0.605874 | 3 | 0 | 3 |
| RFX3 | LUC7L3 | 0.59903 | 5 | 0 | 5 |
| RFX3 | COLEC10 | 0.593251 | 4 | 0 | 3 |
For details and further investigation, click here
