| Full name: hes related family bHLH transcription factor with YRPW motif like | Alias Symbol: bHLHb33|HEY3|HESR3 | ||
| Type: protein-coding gene | Cytoband: 1p34.2 | ||
| Entrez ID: 26508 | HGNC ID: HGNC:4882 | Ensembl Gene: ENSG00000163909 | OMIM ID: 609034 |
| Drug and gene relationship at DGIdb | |||
Expression of HEYL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEYL | 26508 | 226828_s_at | 1.0737 | 0.0756 | |
| GSE20347 | HEYL | 26508 | 220662_s_at | -0.1180 | 0.1809 | |
| GSE23400 | HEYL | 26508 | 220662_s_at | -0.1439 | 0.0000 | |
| GSE26886 | HEYL | 26508 | 226828_s_at | 1.1713 | 0.0000 | |
| GSE29001 | HEYL | 26508 | 220662_s_at | -0.1455 | 0.2504 | |
| GSE38129 | HEYL | 26508 | 220662_s_at | -0.2709 | 0.0084 | |
| GSE45670 | HEYL | 26508 | 220662_s_at | -0.0951 | 0.3898 | |
| GSE53622 | HEYL | 26508 | 96206 | 0.6004 | 0.0000 | |
| GSE53624 | HEYL | 26508 | 96206 | 1.1894 | 0.0000 | |
| GSE63941 | HEYL | 26508 | 220662_s_at | 0.1423 | 0.4305 | |
| GSE77861 | HEYL | 26508 | 220662_s_at | -0.1499 | 0.2314 | |
| GSE97050 | HEYL | 26508 | A_23_P430658 | 0.4075 | 0.1189 | |
| SRP007169 | HEYL | 26508 | RNAseq | 6.3628 | 0.0000 | |
| SRP008496 | HEYL | 26508 | RNAseq | 3.7112 | 0.0000 | |
| SRP064894 | HEYL | 26508 | RNAseq | 1.3833 | 0.0000 | |
| SRP133303 | HEYL | 26508 | RNAseq | 0.7427 | 0.0052 | |
| SRP159526 | HEYL | 26508 | RNAseq | 0.4327 | 0.3141 | |
| SRP193095 | HEYL | 26508 | RNAseq | 2.3109 | 0.0000 | |
| SRP219564 | HEYL | 26508 | RNAseq | 0.9314 | 0.1482 | |
| TCGA | HEYL | 26508 | RNAseq | 0.0223 | 0.8571 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by HEYL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEYL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEYL | 26508 | 3 | 4 | 23 | |
| GSE20123 | HEYL | 26508 | 2 | 3 | 25 | |
| GSE43470 | HEYL | 26508 | 8 | 2 | 33 | |
| GSE46452 | HEYL | 26508 | 4 | 1 | 54 | |
| GSE47630 | HEYL | 26508 | 9 | 2 | 29 | |
| GSE54993 | HEYL | 26508 | 0 | 1 | 69 | |
| GSE54994 | HEYL | 26508 | 13 | 2 | 38 | |
| GSE60625 | HEYL | 26508 | 0 | 0 | 11 | |
| GSE74703 | HEYL | 26508 | 7 | 1 | 28 | |
| GSE74704 | HEYL | 26508 | 1 | 0 | 19 | |
| TCGA | HEYL | 26508 | 16 | 16 | 64 |
Total number of gains: 63; Total number of losses: 32; Total Number of normals: 393.
Somatic mutations of HEYL:
Generating mutation plots.
Highly correlated genes for HEYL:
Showing top 20/767 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEYL | CLDND2 | 0.785351 | 3 | 0 | 3 |
| HEYL | ARG2 | 0.758871 | 3 | 0 | 3 |
| HEYL | LRRC14 | 0.742359 | 3 | 0 | 3 |
| HEYL | SNCA | 0.741949 | 3 | 0 | 3 |
| HEYL | MRPL36 | 0.739173 | 4 | 0 | 4 |
| HEYL | OSCAR | 0.736938 | 3 | 0 | 3 |
| HEYL | FHL3 | 0.734673 | 5 | 0 | 4 |
| HEYL | SPON2 | 0.733683 | 3 | 0 | 3 |
| HEYL | CXCR5 | 0.733101 | 6 | 0 | 6 |
| HEYL | RAB34 | 0.730156 | 3 | 0 | 3 |
| HEYL | GPR12 | 0.729886 | 4 | 0 | 4 |
| HEYL | PLEKHG2 | 0.72709 | 3 | 0 | 3 |
| HEYL | A1BG | 0.723496 | 3 | 0 | 3 |
| HEYL | CNR1 | 0.722592 | 5 | 0 | 5 |
| HEYL | CNTD1 | 0.719684 | 3 | 0 | 3 |
| HEYL | ZNF584 | 0.719436 | 3 | 0 | 3 |
| HEYL | KCNK2 | 0.719097 | 4 | 0 | 3 |
| HEYL | LRRC8C | 0.716386 | 3 | 0 | 3 |
| HEYL | KCNJ3 | 0.716231 | 3 | 0 | 3 |
| HEYL | CYP2A6 | 0.714462 | 6 | 0 | 6 |
For details and further investigation, click here
