| Full name: small integral membrane protein 6 | Alias Symbol: ELN | ||
| Type: protein-coding gene | Cytoband: 17q25.1 | ||
| Entrez ID: 100130933 | HGNC ID: HGNC:40032 | Ensembl Gene: ENSG00000259120 | OMIM ID: |
Screen Evidence:
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Expression of SMIM6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMIM6 | 100130933 | 236098_at | -0.0911 | 0.7419 | |
| GSE26886 | SMIM6 | 100130933 | 236098_at | 0.0650 | 0.5700 | |
| GSE45670 | SMIM6 | 100130933 | 236098_at | 0.0355 | 0.7557 | |
| GSE53622 | SMIM6 | 100130933 | 48213 | -0.4543 | 0.0189 | |
| GSE53624 | SMIM6 | 100130933 | 48213 | -1.0905 | 0.0000 | |
| GSE63941 | SMIM6 | 100130933 | 236098_at | 0.2364 | 0.2197 | |
| GSE77861 | SMIM6 | 100130933 | 236098_at | -0.2609 | 0.0104 | |
| SRP133303 | SMIM6 | 100130933 | RNAseq | 0.2928 | 0.4347 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SMIM6 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SMIM6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMIM6 | 100130933 | 7 | 2 | 21 | |
| GSE20123 | SMIM6 | 100130933 | 7 | 2 | 21 | |
| GSE43470 | SMIM6 | 100130933 | 5 | 3 | 35 | |
| GSE46452 | SMIM6 | 100130933 | 34 | 0 | 25 | |
| GSE47630 | SMIM6 | 100130933 | 8 | 1 | 31 | |
| GSE54993 | SMIM6 | 100130933 | 2 | 5 | 63 | |
| GSE54994 | SMIM6 | 100130933 | 10 | 4 | 39 | |
| GSE60625 | SMIM6 | 100130933 | 6 | 0 | 5 | |
| GSE74703 | SMIM6 | 100130933 | 5 | 1 | 30 | |
| GSE74704 | SMIM6 | 100130933 | 5 | 1 | 14 | |
| TCGA | SMIM6 | 100130933 | 32 | 9 | 55 |
Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.
Somatic mutations of SMIM6:
Generating mutation plots.
Highly correlated genes for SMIM6:
Showing top 20/101 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMIM6 | TTR | 0.747364 | 4 | 0 | 4 |
| SMIM6 | FAM186B | 0.727214 | 3 | 0 | 3 |
| SMIM6 | GRM7 | 0.698956 | 3 | 0 | 3 |
| SMIM6 | SCN4A | 0.687963 | 3 | 0 | 3 |
| SMIM6 | NR0B2 | 0.682653 | 4 | 0 | 3 |
| SMIM6 | KRT20 | 0.681023 | 3 | 0 | 3 |
| SMIM6 | MYO1A | 0.674408 | 5 | 0 | 4 |
| SMIM6 | AMER3 | 0.666662 | 3 | 0 | 3 |
| SMIM6 | ETNPPL | 0.662825 | 3 | 0 | 3 |
| SMIM6 | NLRP12 | 0.662409 | 3 | 0 | 3 |
| SMIM6 | ATP4A | 0.659099 | 4 | 0 | 4 |
| SMIM6 | A4GNT | 0.654137 | 3 | 0 | 3 |
| SMIM6 | SIX6 | 0.65084 | 3 | 0 | 3 |
| SMIM6 | TFF1 | 0.646114 | 3 | 0 | 3 |
| SMIM6 | SULT1C2 | 0.638158 | 4 | 0 | 3 |
| SMIM6 | NACAD | 0.63726 | 3 | 0 | 3 |
| SMIM6 | LAMA1 | 0.634404 | 3 | 0 | 3 |
| SMIM6 | CACNG8 | 0.632639 | 4 | 0 | 3 |
| SMIM6 | TMEM59L | 0.629084 | 3 | 0 | 3 |
| SMIM6 | SST | 0.628839 | 4 | 0 | 4 |
For details and further investigation, click here
