| Full name: family with sequence similarity 186 member A | Alias Symbol: LOC121006 | ||
| Type: protein-coding gene | Cytoband: 12q13.12 | ||
| Entrez ID: 121006 | HGNC ID: HGNC:26980 | Ensembl Gene: ENSG00000185958 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of FAM186A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM186A | 121006 | 1562317_at | -0.0506 | 0.8436 | |
| GSE20347 | FAM186A | 121006 | 216595_at | 0.1044 | 0.0719 | |
| GSE23400 | FAM186A | 121006 | 216595_at | -0.0378 | 0.1204 | |
| GSE26886 | FAM186A | 121006 | 216595_at | 0.1253 | 0.2560 | |
| GSE29001 | FAM186A | 121006 | 216595_at | 0.0482 | 0.7166 | |
| GSE38129 | FAM186A | 121006 | 216595_at | 0.1103 | 0.0564 | |
| GSE45670 | FAM186A | 121006 | 1562317_at | 0.0741 | 0.2060 | |
| GSE53622 | FAM186A | 121006 | 53377 | -0.1580 | 0.3387 | |
| GSE53624 | FAM186A | 121006 | 53377 | -0.1468 | 0.0892 | |
| GSE63941 | FAM186A | 121006 | 216595_at | 0.0476 | 0.8810 | |
| GSE77861 | FAM186A | 121006 | 1562317_at | -0.0616 | 0.5034 | |
| GSE97050 | FAM186A | 121006 | A_33_P3282060 | 0.0801 | 0.6997 | |
| SRP133303 | FAM186A | 121006 | RNAseq | -0.1090 | 0.7493 | |
| TCGA | FAM186A | 121006 | RNAseq | -0.4488 | 0.2583 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM186A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM186A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM186A | 121006 | 8 | 1 | 21 | |
| GSE20123 | FAM186A | 121006 | 8 | 1 | 21 | |
| GSE43470 | FAM186A | 121006 | 3 | 0 | 40 | |
| GSE46452 | FAM186A | 121006 | 8 | 1 | 50 | |
| GSE47630 | FAM186A | 121006 | 11 | 2 | 27 | |
| GSE54993 | FAM186A | 121006 | 0 | 5 | 65 | |
| GSE54994 | FAM186A | 121006 | 3 | 2 | 48 | |
| GSE60625 | FAM186A | 121006 | 0 | 0 | 11 | |
| GSE74703 | FAM186A | 121006 | 3 | 0 | 33 | |
| GSE74704 | FAM186A | 121006 | 5 | 1 | 14 | |
| TCGA | FAM186A | 121006 | 14 | 11 | 71 |
Total number of gains: 63; Total number of losses: 24; Total Number of normals: 401.
Somatic mutations of FAM186A:
Generating mutation plots.
Highly correlated genes for FAM186A:
Showing top 20/199 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM186A | GNG8 | 0.725005 | 3 | 0 | 3 |
| FAM186A | KRTAP1-1 | 0.699056 | 3 | 0 | 3 |
| FAM186A | LINC00408 | 0.676697 | 3 | 0 | 3 |
| FAM186A | CACNA1A | 0.675304 | 3 | 0 | 3 |
| FAM186A | CAPN13 | 0.670799 | 3 | 0 | 3 |
| FAM186A | C2orf73 | 0.655189 | 3 | 0 | 3 |
| FAM186A | PHOSPHO1 | 0.654139 | 3 | 0 | 3 |
| FAM186A | TEKT1 | 0.65333 | 4 | 0 | 3 |
| FAM186A | PAX3 | 0.644855 | 4 | 0 | 3 |
| FAM186A | SMOC1 | 0.642697 | 4 | 0 | 3 |
| FAM186A | NACAD | 0.639629 | 4 | 0 | 3 |
| FAM186A | SLC8A3 | 0.637469 | 3 | 0 | 3 |
| FAM186A | GAS2L2 | 0.631235 | 3 | 0 | 3 |
| FAM186A | PRX | 0.627797 | 3 | 0 | 3 |
| FAM186A | CITED1 | 0.622836 | 4 | 0 | 3 |
| FAM186A | TSPAN16 | 0.622584 | 3 | 0 | 3 |
| FAM186A | TDRD1 | 0.621917 | 4 | 0 | 4 |
| FAM186A | C10orf91 | 0.619916 | 4 | 0 | 4 |
| FAM186A | TLX2 | 0.618482 | 4 | 0 | 3 |
| FAM186A | CRABP1 | 0.618305 | 4 | 0 | 4 |
For details and further investigation, click here
