| Full name: ATPase H+/K+ transporting subunit beta | Alias Symbol: ATP6B | ||
| Type: protein-coding gene | Cytoband: 13q34 | ||
| Entrez ID: 496 | HGNC ID: HGNC:820 | Ensembl Gene: ENSG00000186009 | OMIM ID: 137217 |
| Drug and gene relationship at DGIdb | |||
Expression of ATP4B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATP4B | 496 | 1563405_at | -0.0768 | 0.7504 | |
| GSE20347 | ATP4B | 496 | 207546_at | 0.0750 | 0.3153 | |
| GSE23400 | ATP4B | 496 | 207546_at | -0.1597 | 0.0709 | |
| GSE26886 | ATP4B | 496 | 1563405_at | 0.0831 | 0.5034 | |
| GSE29001 | ATP4B | 496 | 207546_at | -0.1050 | 0.3262 | |
| GSE38129 | ATP4B | 496 | 207546_at | -0.7000 | 0.1704 | |
| GSE45670 | ATP4B | 496 | 1563405_at | 0.0334 | 0.7242 | |
| GSE53622 | ATP4B | 496 | 30470 | -0.0629 | 0.8739 | |
| GSE53624 | ATP4B | 496 | 30470 | 0.5151 | 0.0395 | |
| GSE63941 | ATP4B | 496 | 1563405_at | 0.2725 | 0.0657 | |
| GSE77861 | ATP4B | 496 | 1563407_x_at | -0.0621 | 0.5719 | |
| TCGA | ATP4B | 496 | RNAseq | -6.8192 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATP4B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATP4B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATP4B | 496 | 6 | 12 | 12 | |
| GSE20123 | ATP4B | 496 | 6 | 11 | 13 | |
| GSE43470 | ATP4B | 496 | 4 | 13 | 26 | |
| GSE46452 | ATP4B | 496 | 3 | 31 | 25 | |
| GSE47630 | ATP4B | 496 | 3 | 26 | 11 | |
| GSE54993 | ATP4B | 496 | 12 | 3 | 55 | |
| GSE54994 | ATP4B | 496 | 9 | 10 | 34 | |
| GSE60625 | ATP4B | 496 | 0 | 3 | 8 | |
| GSE74703 | ATP4B | 496 | 3 | 10 | 23 | |
| GSE74704 | ATP4B | 496 | 4 | 9 | 7 | |
| TCGA | ATP4B | 496 | 19 | 31 | 46 |
Total number of gains: 69; Total number of losses: 159; Total Number of normals: 260.
Somatic mutations of ATP4B:
Generating mutation plots.
Highly correlated genes for ATP4B:
Showing top 20/330 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATP4B | CLDN18 | 0.748749 | 6 | 0 | 6 |
| ATP4B | REG1A | 0.716474 | 6 | 0 | 6 |
| ATP4B | MUC6 | 0.707469 | 5 | 0 | 4 |
| ATP4B | OR2H2 | 0.684968 | 4 | 0 | 4 |
| ATP4B | CTSE | 0.679764 | 7 | 0 | 5 |
| ATP4B | ETNPPL | 0.6789 | 5 | 0 | 4 |
| ATP4B | SCGB1D1 | 0.678577 | 3 | 0 | 3 |
| ATP4B | ARPP21 | 0.677189 | 3 | 0 | 3 |
| ATP4B | REEP2 | 0.675026 | 5 | 0 | 4 |
| ATP4B | FUT9 | 0.671103 | 5 | 0 | 4 |
| ATP4B | GC | 0.661789 | 6 | 0 | 5 |
| ATP4B | LINC01019 | 0.656823 | 3 | 0 | 3 |
| ATP4B | CIITA | 0.655807 | 4 | 0 | 4 |
| ATP4B | PPP1R17 | 0.655334 | 3 | 0 | 3 |
| ATP4B | PLA2G1B | 0.648496 | 6 | 0 | 6 |
| ATP4B | FGA | 0.647663 | 6 | 0 | 5 |
| ATP4B | A1CF | 0.646953 | 4 | 0 | 3 |
| ATP4B | CHIA | 0.644792 | 8 | 0 | 6 |
| ATP4B | CAPN11 | 0.642724 | 3 | 0 | 3 |
| ATP4B | FNDC8 | 0.641483 | 3 | 0 | 3 |
For details and further investigation, click here
