| Full name: testin LIM domain protein | Alias Symbol: DKFZP586B2022|TESS-2|TESTIN | ||
| Type: protein-coding gene | Cytoband: 7q31.2 | ||
| Entrez ID: 26136 | HGNC ID: HGNC:14620 | Ensembl Gene: ENSG00000135269 | OMIM ID: 606085 |
| Drug and gene relationship at DGIdb | |||
Expression of TES:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TES | 26136 | 202720_at | -0.3262 | 0.4150 | |
| GSE20347 | TES | 26136 | 202720_at | 0.1691 | 0.4307 | |
| GSE23400 | TES | 26136 | 202720_at | 0.2137 | 0.0227 | |
| GSE26886 | TES | 26136 | 202720_at | 0.4328 | 0.0848 | |
| GSE29001 | TES | 26136 | 202720_at | 0.1567 | 0.5506 | |
| GSE38129 | TES | 26136 | 202720_at | 0.0042 | 0.9846 | |
| GSE45670 | TES | 26136 | 202720_at | -0.0787 | 0.7392 | |
| GSE53622 | TES | 26136 | 37863 | 0.0811 | 0.4383 | |
| GSE53624 | TES | 26136 | 37863 | -0.0393 | 0.7139 | |
| GSE63941 | TES | 26136 | 202720_at | 0.1098 | 0.8441 | |
| GSE77861 | TES | 26136 | 202720_at | 0.4372 | 0.0488 | |
| GSE97050 | TES | 26136 | A_23_P111672 | 0.0958 | 0.8229 | |
| SRP007169 | TES | 26136 | RNAseq | 1.3132 | 0.0004 | |
| SRP008496 | TES | 26136 | RNAseq | 1.2913 | 0.0000 | |
| SRP064894 | TES | 26136 | RNAseq | 0.0977 | 0.5547 | |
| SRP133303 | TES | 26136 | RNAseq | 0.6567 | 0.0006 | |
| SRP159526 | TES | 26136 | RNAseq | -0.2516 | 0.4878 | |
| SRP193095 | TES | 26136 | RNAseq | 0.1473 | 0.3589 | |
| SRP219564 | TES | 26136 | RNAseq | 0.0610 | 0.8741 | |
| TCGA | TES | 26136 | RNAseq | -0.1706 | 0.0021 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by TES expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TES:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TES | 26136 | 10 | 2 | 18 | |
| GSE20123 | TES | 26136 | 11 | 2 | 17 | |
| GSE43470 | TES | 26136 | 3 | 2 | 38 | |
| GSE46452 | TES | 26136 | 8 | 1 | 50 | |
| GSE47630 | TES | 26136 | 7 | 4 | 29 | |
| GSE54993 | TES | 26136 | 2 | 7 | 61 | |
| GSE54994 | TES | 26136 | 12 | 5 | 36 | |
| GSE60625 | TES | 26136 | 0 | 0 | 11 | |
| GSE74703 | TES | 26136 | 3 | 2 | 31 | |
| GSE74704 | TES | 26136 | 7 | 2 | 11 | |
| TCGA | TES | 26136 | 33 | 17 | 46 |
Total number of gains: 96; Total number of losses: 44; Total Number of normals: 348.
Somatic mutations of TES:
Generating mutation plots.
Highly correlated genes for TES:
Showing top 20/526 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TES | UBXN10 | 0.790388 | 3 | 0 | 3 |
| TES | ZFAND2A | 0.758987 | 3 | 0 | 3 |
| TES | BCAS2 | 0.742816 | 3 | 0 | 3 |
| TES | CYP2U1 | 0.739278 | 3 | 0 | 3 |
| TES | ZBTB26 | 0.735594 | 3 | 0 | 3 |
| TES | CDC27 | 0.734677 | 3 | 0 | 3 |
| TES | FGF12 | 0.728987 | 3 | 0 | 3 |
| TES | CAMK2G | 0.723224 | 3 | 0 | 3 |
| TES | PCOLCE2 | 0.721148 | 3 | 0 | 3 |
| TES | LDLR | 0.720686 | 3 | 0 | 3 |
| TES | FNIP2 | 0.7202 | 3 | 0 | 3 |
| TES | C3orf70 | 0.715858 | 4 | 0 | 4 |
| TES | PSMD4 | 0.709415 | 3 | 0 | 3 |
| TES | PCBP2 | 0.707771 | 3 | 0 | 3 |
| TES | ATIC | 0.700154 | 3 | 0 | 3 |
| TES | STAT2 | 0.695769 | 3 | 0 | 3 |
| TES | IRF2BP2 | 0.693622 | 4 | 0 | 4 |
| TES | SNAPC5 | 0.692567 | 4 | 0 | 4 |
| TES | POPDC2 | 0.690977 | 4 | 0 | 4 |
| TES | ZBTB25 | 0.68735 | 4 | 0 | 4 |
For details and further investigation, click here
