| Full name: estrogen related receptor gamma | Alias Symbol: NR3B3|ERRg|ERR-gamma | ||
| Type: protein-coding gene | Cytoband: 1q41 | ||
| Entrez ID: 2104 | HGNC ID: HGNC:3474 | Ensembl Gene: ENSG00000196482 | OMIM ID: 602969 |
| Drug and gene relationship at DGIdb | |||
Expression of ESRRG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ESRRG | 2104 | 209966_x_at | -0.7524 | 0.4098 | |
| GSE20347 | ESRRG | 2104 | 209966_x_at | -0.0671 | 0.5860 | |
| GSE23400 | ESRRG | 2104 | 209966_x_at | -0.0942 | 0.0121 | |
| GSE26886 | ESRRG | 2104 | 209966_x_at | 0.1005 | 0.5999 | |
| GSE29001 | ESRRG | 2104 | 209966_x_at | 0.2349 | 0.5608 | |
| GSE38129 | ESRRG | 2104 | 209966_x_at | -0.7914 | 0.0151 | |
| GSE45670 | ESRRG | 2104 | 209966_x_at | -0.2580 | 0.0278 | |
| GSE53622 | ESRRG | 2104 | 3149 | -1.4472 | 0.0000 | |
| GSE53624 | ESRRG | 2104 | 3149 | -0.6282 | 0.0000 | |
| GSE63941 | ESRRG | 2104 | 209966_x_at | 0.2146 | 0.5724 | |
| GSE77861 | ESRRG | 2104 | 209966_x_at | 0.0022 | 0.9834 | |
| GSE97050 | ESRRG | 2104 | A_24_P7965 | -1.3813 | 0.1235 | |
| SRP064894 | ESRRG | 2104 | RNAseq | -1.1504 | 0.0106 | |
| SRP133303 | ESRRG | 2104 | RNAseq | -0.2479 | 0.6693 | |
| SRP159526 | ESRRG | 2104 | RNAseq | -0.3276 | 0.4681 | |
| SRP219564 | ESRRG | 2104 | RNAseq | -0.4984 | 0.6026 | |
| TCGA | ESRRG | 2104 | RNAseq | -3.1609 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by ESRRG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ESRRG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ESRRG | 2104 | 9 | 0 | 21 | |
| GSE20123 | ESRRG | 2104 | 9 | 0 | 21 | |
| GSE43470 | ESRRG | 2104 | 7 | 1 | 35 | |
| GSE46452 | ESRRG | 2104 | 3 | 1 | 55 | |
| GSE47630 | ESRRG | 2104 | 15 | 0 | 25 | |
| GSE54993 | ESRRG | 2104 | 0 | 6 | 64 | |
| GSE54994 | ESRRG | 2104 | 14 | 0 | 39 | |
| GSE60625 | ESRRG | 2104 | 0 | 0 | 11 | |
| GSE74703 | ESRRG | 2104 | 7 | 1 | 28 | |
| GSE74704 | ESRRG | 2104 | 3 | 0 | 17 | |
| TCGA | ESRRG | 2104 | 44 | 3 | 49 |
Total number of gains: 111; Total number of losses: 12; Total Number of normals: 365.
Somatic mutations of ESRRG:
Generating mutation plots.
Highly correlated genes for ESRRG:
Showing top 20/721 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ESRRG | RGMB | 0.802901 | 3 | 0 | 3 |
| ESRRG | C1QTNF7 | 0.798304 | 3 | 0 | 3 |
| ESRRG | CC2D2A | 0.773231 | 3 | 0 | 3 |
| ESRRG | KLHL41 | 0.765953 | 3 | 0 | 3 |
| ESRRG | KLHL23 | 0.761509 | 3 | 0 | 3 |
| ESRRG | UBXN10 | 0.755809 | 3 | 0 | 3 |
| ESRRG | PPP1R14A | 0.748608 | 3 | 0 | 3 |
| ESRRG | HSPA12A | 0.736103 | 3 | 0 | 3 |
| ESRRG | VIP | 0.729605 | 5 | 0 | 5 |
| ESRRG | SGCG | 0.719586 | 5 | 0 | 4 |
| ESRRG | CADM2 | 0.716461 | 4 | 0 | 3 |
| ESRRG | BVES | 0.714362 | 4 | 0 | 4 |
| ESRRG | PALLD | 0.71385 | 3 | 0 | 3 |
| ESRRG | SGCA | 0.712572 | 6 | 0 | 5 |
| ESRRG | SMTN | 0.710418 | 4 | 0 | 3 |
| ESRRG | CFL2 | 0.709149 | 3 | 0 | 3 |
| ESRRG | PDZRN4 | 0.708367 | 6 | 0 | 5 |
| ESRRG | TOR1AIP1 | 0.707707 | 4 | 0 | 4 |
| ESRRG | IL17D | 0.705128 | 3 | 0 | 3 |
| ESRRG | TMEM8B | 0.703254 | 5 | 0 | 5 |
For details and further investigation, click here
