| Full name: regulator of cell cycle | Alias Symbol: bA157L14.2|RGC-32|RGC32 | ||
| Type: protein-coding gene | Cytoband: 13q14.11 | ||
| Entrez ID: 28984 | HGNC ID: HGNC:20369 | Ensembl Gene: ENSG00000102760 | OMIM ID: 610077 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RGCC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RGCC | 28984 | 218723_s_at | 0.1709 | 0.8535 | |
| GSE20347 | RGCC | 28984 | 218723_s_at | -0.4671 | 0.0395 | |
| GSE23400 | RGCC | 28984 | 218723_s_at | 0.1371 | 0.2797 | |
| GSE26886 | RGCC | 28984 | 218723_s_at | 1.5200 | 0.0027 | |
| GSE29001 | RGCC | 28984 | 218723_s_at | -0.8249 | 0.0715 | |
| GSE38129 | RGCC | 28984 | 218723_s_at | -0.3720 | 0.1899 | |
| GSE45670 | RGCC | 28984 | 218723_s_at | -0.4462 | 0.0981 | |
| GSE53622 | RGCC | 28984 | 127507 | 0.4179 | 0.0000 | |
| GSE53624 | RGCC | 28984 | 127507 | 0.1533 | 0.1172 | |
| GSE63941 | RGCC | 28984 | 218723_s_at | -1.1489 | 0.5211 | |
| GSE77861 | RGCC | 28984 | 218723_s_at | 0.1053 | 0.9075 | |
| SRP007169 | RGCC | 28984 | RNAseq | -0.3286 | 0.5980 | |
| SRP008496 | RGCC | 28984 | RNAseq | 0.0596 | 0.8816 | |
| SRP064894 | RGCC | 28984 | RNAseq | 0.7927 | 0.0021 | |
| SRP133303 | RGCC | 28984 | RNAseq | 0.2056 | 0.2826 | |
| SRP159526 | RGCC | 28984 | RNAseq | 0.1502 | 0.6617 | |
| SRP193095 | RGCC | 28984 | RNAseq | 0.6160 | 0.0006 | |
| SRP219564 | RGCC | 28984 | RNAseq | 0.2619 | 0.5775 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RGCC expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of RGCC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RGCC | 28984 | 0 | 13 | 17 | |
| GSE20123 | RGCC | 28984 | 0 | 12 | 18 | |
| GSE43470 | RGCC | 28984 | 3 | 13 | 27 | |
| GSE46452 | RGCC | 28984 | 0 | 33 | 26 | |
| GSE47630 | RGCC | 28984 | 2 | 27 | 11 | |
| GSE54993 | RGCC | 28984 | 12 | 2 | 56 | |
| GSE54994 | RGCC | 28984 | 1 | 16 | 36 | |
| GSE60625 | RGCC | 28984 | 0 | 3 | 8 | |
| GSE74703 | RGCC | 28984 | 3 | 10 | 23 | |
| GSE74704 | RGCC | 28984 | 0 | 9 | 11 | |
| TCGA | RGCC | 28984 | 8 | 40 | 48 |
Total number of gains: 29; Total number of losses: 178; Total Number of normals: 281.
Somatic mutations of RGCC:
Generating mutation plots.
Highly correlated genes for RGCC:
Showing top 20/127 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RGCC | TOX2 | 0.655245 | 3 | 0 | 3 |
| RGCC | RASA3 | 0.654192 | 4 | 0 | 3 |
| RGCC | KATNAL1 | 0.618183 | 4 | 0 | 3 |
| RGCC | CEP120 | 0.617285 | 3 | 0 | 3 |
| RGCC | DCHS1 | 0.602782 | 6 | 0 | 6 |
| RGCC | PACSIN2 | 0.599871 | 4 | 0 | 4 |
| RGCC | DYRK3 | 0.599185 | 4 | 0 | 3 |
| RGCC | COL4A2 | 0.592405 | 5 | 0 | 4 |
| RGCC | NID2 | 0.590928 | 6 | 0 | 5 |
| RGCC | EDNRB | 0.590537 | 4 | 0 | 4 |
| RGCC | EFEMP2 | 0.58828 | 8 | 0 | 6 |
| RGCC | SGTB | 0.580209 | 4 | 0 | 3 |
| RGCC | LAMA4 | 0.578503 | 7 | 0 | 5 |
| RGCC | COL12A1 | 0.576892 | 5 | 0 | 4 |
| RGCC | LAMC1 | 0.576468 | 7 | 0 | 5 |
| RGCC | DOCK11 | 0.576194 | 4 | 0 | 3 |
| RGCC | RHOQ | 0.575931 | 5 | 0 | 3 |
| RGCC | TGFBR2 | 0.575877 | 6 | 0 | 4 |
| RGCC | PDE4A | 0.573365 | 5 | 0 | 3 |
| RGCC | ARHGAP36 | 0.572436 | 4 | 0 | 3 |
For details and further investigation, click here
