| Full name: synaptotagmin 4 | Alias Symbol: KIAA1342|HsT1192 | ||
| Type: protein-coding gene | Cytoband: 18q12.3 | ||
| Entrez ID: 6860 | HGNC ID: HGNC:11512 | Ensembl Gene: ENSG00000132872 | OMIM ID: 600103 |
| Drug and gene relationship at DGIdb | |||
Expression of SYT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYT4 | 6860 | 223529_at | -0.0853 | 0.8585 | |
| GSE26886 | SYT4 | 6860 | 223529_at | 0.0059 | 0.9660 | |
| GSE45670 | SYT4 | 6860 | 223529_at | 0.1900 | 0.4445 | |
| GSE53622 | SYT4 | 6860 | 17460 | -0.2293 | 0.4993 | |
| GSE53624 | SYT4 | 6860 | 17460 | -0.1412 | 0.5387 | |
| GSE63941 | SYT4 | 6860 | 223529_at | -0.1483 | 0.3994 | |
| GSE77861 | SYT4 | 6860 | 223529_at | -0.0381 | 0.6793 | |
| TCGA | SYT4 | 6860 | RNAseq | -4.3720 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SYT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYT4 | 6860 | 1 | 6 | 23 | |
| GSE20123 | SYT4 | 6860 | 1 | 6 | 23 | |
| GSE43470 | SYT4 | 6860 | 0 | 4 | 39 | |
| GSE46452 | SYT4 | 6860 | 1 | 25 | 33 | |
| GSE47630 | SYT4 | 6860 | 5 | 20 | 15 | |
| GSE54993 | SYT4 | 6860 | 8 | 1 | 61 | |
| GSE54994 | SYT4 | 6860 | 2 | 15 | 36 | |
| GSE60625 | SYT4 | 6860 | 0 | 4 | 7 | |
| GSE74703 | SYT4 | 6860 | 0 | 3 | 33 | |
| GSE74704 | SYT4 | 6860 | 0 | 4 | 16 | |
| TCGA | SYT4 | 6860 | 13 | 40 | 43 |
Total number of gains: 31; Total number of losses: 128; Total Number of normals: 329.
Somatic mutations of SYT4:
Generating mutation plots.
Highly correlated genes for SYT4:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYT4 | SH3GL2 | 0.723596 | 4 | 0 | 4 |
| SYT4 | VIP | 0.70143 | 3 | 0 | 3 |
| SYT4 | NPY | 0.686498 | 3 | 0 | 3 |
| SYT4 | STMN2 | 0.684301 | 4 | 0 | 3 |
| SYT4 | NDST4 | 0.671004 | 4 | 0 | 3 |
| SYT4 | BRINP3 | 0.670799 | 3 | 0 | 3 |
| SYT4 | RFX6 | 0.668831 | 3 | 0 | 3 |
| SYT4 | SNAP91 | 0.668165 | 4 | 0 | 3 |
| SYT4 | S100A7A | 0.661434 | 3 | 0 | 3 |
| SYT4 | SLC35F1 | 0.656657 | 4 | 0 | 3 |
| SYT4 | DPP10 | 0.641607 | 5 | 0 | 3 |
| SYT4 | KCNF1 | 0.635562 | 4 | 0 | 3 |
| SYT4 | SPAG8 | 0.628467 | 3 | 0 | 3 |
| SYT4 | SST | 0.626834 | 3 | 0 | 3 |
| SYT4 | KIF5C | 0.614922 | 5 | 0 | 3 |
| SYT4 | XKR7 | 0.607925 | 3 | 0 | 3 |
| SYT4 | MUC19 | 0.607909 | 4 | 0 | 3 |
| SYT4 | CDHR3 | 0.607364 | 4 | 0 | 3 |
| SYT4 | NRXN1 | 0.586828 | 4 | 0 | 3 |
| SYT4 | KLHL4 | 0.584975 | 4 | 0 | 3 |
For details and further investigation, click here
