| Full name: rhomboid domain containing 3 | Alias Symbol: PTAG | ||
| Type: protein-coding gene | Cytoband: 22q12.2 | ||
| Entrez ID: 25807 | HGNC ID: HGNC:1308 | Ensembl Gene: ENSG00000100263 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RHBDD3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RHBDD3 | 25807 | 204402_at | 0.4698 | 0.1946 | |
| GSE20347 | RHBDD3 | 25807 | 204402_at | 0.2019 | 0.1417 | |
| GSE23400 | RHBDD3 | 25807 | 204402_at | 0.1504 | 0.0022 | |
| GSE26886 | RHBDD3 | 25807 | 204402_at | 0.4641 | 0.0137 | |
| GSE29001 | RHBDD3 | 25807 | 204402_at | 0.4024 | 0.0905 | |
| GSE38129 | RHBDD3 | 25807 | 204402_at | 0.4316 | 0.0000 | |
| GSE45670 | RHBDD3 | 25807 | 217622_at | 0.1382 | 0.1209 | |
| GSE53622 | RHBDD3 | 25807 | 95038 | 0.4738 | 0.0000 | |
| GSE53624 | RHBDD3 | 25807 | 95038 | 0.6468 | 0.0000 | |
| GSE63941 | RHBDD3 | 25807 | 204402_at | -0.5108 | 0.1235 | |
| GSE77861 | RHBDD3 | 25807 | 204402_at | -0.0759 | 0.7686 | |
| GSE97050 | RHBDD3 | 25807 | A_33_P3330731 | 0.1959 | 0.4563 | |
| SRP007169 | RHBDD3 | 25807 | RNAseq | 0.6185 | 0.1951 | |
| SRP008496 | RHBDD3 | 25807 | RNAseq | 0.2319 | 0.4802 | |
| SRP064894 | RHBDD3 | 25807 | RNAseq | 1.2303 | 0.0000 | |
| SRP133303 | RHBDD3 | 25807 | RNAseq | 0.7347 | 0.0003 | |
| SRP159526 | RHBDD3 | 25807 | RNAseq | 1.1882 | 0.0003 | |
| SRP193095 | RHBDD3 | 25807 | RNAseq | 0.7809 | 0.0000 | |
| SRP219564 | RHBDD3 | 25807 | RNAseq | 1.0980 | 0.0037 | |
| TCGA | RHBDD3 | 25807 | RNAseq | 0.2607 | 0.0001 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by RHBDD3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RHBDD3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RHBDD3 | 25807 | 3 | 5 | 22 | |
| GSE20123 | RHBDD3 | 25807 | 3 | 4 | 23 | |
| GSE43470 | RHBDD3 | 25807 | 4 | 5 | 34 | |
| GSE46452 | RHBDD3 | 25807 | 31 | 1 | 27 | |
| GSE47630 | RHBDD3 | 25807 | 8 | 5 | 27 | |
| GSE54993 | RHBDD3 | 25807 | 3 | 6 | 61 | |
| GSE54994 | RHBDD3 | 25807 | 11 | 8 | 34 | |
| GSE60625 | RHBDD3 | 25807 | 5 | 0 | 6 | |
| GSE74703 | RHBDD3 | 25807 | 4 | 4 | 28 | |
| GSE74704 | RHBDD3 | 25807 | 0 | 1 | 19 | |
| TCGA | RHBDD3 | 25807 | 26 | 16 | 54 |
Total number of gains: 98; Total number of losses: 55; Total Number of normals: 335.
Somatic mutations of RHBDD3:
Generating mutation plots.
Highly correlated genes for RHBDD3:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RHBDD3 | MRGPRG | 0.80835 | 3 | 0 | 3 |
| RHBDD3 | TMEM235 | 0.791127 | 3 | 0 | 3 |
| RHBDD3 | KCNH3 | 0.777871 | 3 | 0 | 3 |
| RHBDD3 | MS4A18 | 0.771111 | 3 | 0 | 3 |
| RHBDD3 | C2CD4D | 0.770727 | 3 | 0 | 3 |
| RHBDD3 | SHISA7 | 0.76557 | 3 | 0 | 3 |
| RHBDD3 | LHB | 0.761918 | 3 | 0 | 3 |
| RHBDD3 | CABP4 | 0.754407 | 3 | 0 | 3 |
| RHBDD3 | C9orf153 | 0.75255 | 3 | 0 | 3 |
| RHBDD3 | LRFN4 | 0.751619 | 5 | 0 | 5 |
| RHBDD3 | FUT1 | 0.749295 | 4 | 0 | 4 |
| RHBDD3 | GDPD5 | 0.748957 | 3 | 0 | 3 |
| RHBDD3 | C19orf71 | 0.747494 | 3 | 0 | 3 |
| RHBDD3 | TCTE1 | 0.74512 | 3 | 0 | 3 |
| RHBDD3 | FOXE3 | 0.733658 | 3 | 0 | 3 |
| RHBDD3 | DNAH10OS | 0.729571 | 3 | 0 | 3 |
| RHBDD3 | IGSF9B | 0.728522 | 3 | 0 | 3 |
| RHBDD3 | OR2A5 | 0.727375 | 3 | 0 | 3 |
| RHBDD3 | OR2T1 | 0.727161 | 3 | 0 | 3 |
| RHBDD3 | IFITM5 | 0.72686 | 3 | 0 | 3 |
For details and further investigation, click here
