| Full name: interferon induced transmembrane protein 5 | Alias Symbol: fragilis4|Hrmp1|BRIL|DSPA1 | ||
| Type: protein-coding gene | Cytoband: 11p15.5 | ||
| Entrez ID: 387733 | HGNC ID: HGNC:16644 | Ensembl Gene: ENSG00000206013 | OMIM ID: 614757 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of IFITM5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | IFITM5 | 387733 | 43937 | 0.4140 | 0.0000 | |
| GSE53624 | IFITM5 | 387733 | 43937 | 0.6374 | 0.0000 | |
| GSE97050 | IFITM5 | 387733 | A_33_P3352995 | 0.1454 | 0.4735 | |
| TCGA | IFITM5 | 387733 | RNAseq | 1.6073 | 0.1928 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IFITM5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IFITM5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IFITM5 | 387733 | 1 | 11 | 18 | |
| GSE20123 | IFITM5 | 387733 | 1 | 12 | 17 | |
| GSE43470 | IFITM5 | 387733 | 1 | 10 | 32 | |
| GSE46452 | IFITM5 | 387733 | 7 | 8 | 44 | |
| GSE47630 | IFITM5 | 387733 | 4 | 12 | 24 | |
| GSE54993 | IFITM5 | 387733 | 3 | 2 | 65 | |
| GSE54994 | IFITM5 | 387733 | 1 | 12 | 40 | |
| GSE60625 | IFITM5 | 387733 | 0 | 0 | 11 | |
| GSE74703 | IFITM5 | 387733 | 1 | 8 | 27 | |
| GSE74704 | IFITM5 | 387733 | 0 | 8 | 12 | |
| TCGA | IFITM5 | 387733 | 8 | 38 | 50 |
Total number of gains: 27; Total number of losses: 121; Total Number of normals: 340.
Somatic mutations of IFITM5:
Generating mutation plots.
Highly correlated genes for IFITM5:
Showing top 20/117 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IFITM5 | TRIM46 | 0.743901 | 3 | 0 | 3 |
| IFITM5 | MC1R | 0.736223 | 3 | 0 | 3 |
| IFITM5 | FAM181A | 0.733144 | 3 | 0 | 3 |
| IFITM5 | RHBDD3 | 0.72686 | 3 | 0 | 3 |
| IFITM5 | SLC26A1 | 0.719499 | 3 | 0 | 3 |
| IFITM5 | CHST10 | 0.718996 | 3 | 0 | 3 |
| IFITM5 | FFAR1 | 0.717069 | 3 | 0 | 3 |
| IFITM5 | DEFB121 | 0.71406 | 3 | 0 | 3 |
| IFITM5 | CBX8 | 0.710762 | 3 | 0 | 3 |
| IFITM5 | LRFN4 | 0.709658 | 3 | 0 | 3 |
| IFITM5 | CPNE7 | 0.7092 | 3 | 0 | 3 |
| IFITM5 | SLC6A3 | 0.709031 | 3 | 0 | 3 |
| IFITM5 | PDZD7 | 0.707853 | 3 | 0 | 3 |
| IFITM5 | OR2T1 | 0.706017 | 3 | 0 | 3 |
| IFITM5 | PRDM13 | 0.705964 | 3 | 0 | 3 |
| IFITM5 | KCNK9 | 0.705061 | 3 | 0 | 3 |
| IFITM5 | LHB | 0.699952 | 3 | 0 | 3 |
| IFITM5 | FAM71F1 | 0.69826 | 3 | 0 | 3 |
| IFITM5 | E2F1 | 0.697053 | 3 | 0 | 3 |
| IFITM5 | ZDHHC19 | 0.696247 | 3 | 0 | 3 |
For details and further investigation, click here
