| Full name: RIC3 acetylcholine receptor chaperone | Alias Symbol: FLJ11608|PRO1385|AYST720 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 79608 | HGNC ID: HGNC:30338 | Ensembl Gene: ENSG00000166405 | OMIM ID: 610509 |
| Drug and gene relationship at DGIdb | |||
Expression of RIC3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RIC3 | 79608 | 220282_at | -0.4631 | 0.1889 | |
| GSE20347 | RIC3 | 79608 | 220282_at | -0.1676 | 0.0973 | |
| GSE23400 | RIC3 | 79608 | 220282_at | -0.2468 | 0.0000 | |
| GSE26886 | RIC3 | 79608 | 220282_at | -0.1389 | 0.2140 | |
| GSE29001 | RIC3 | 79608 | 220282_at | -0.3411 | 0.0061 | |
| GSE38129 | RIC3 | 79608 | 220282_at | -0.2659 | 0.0003 | |
| GSE45670 | RIC3 | 79608 | 220282_at | -0.0845 | 0.5742 | |
| GSE53622 | RIC3 | 79608 | 122255 | -2.2210 | 0.0000 | |
| GSE53624 | RIC3 | 79608 | 122255 | -2.8790 | 0.0000 | |
| GSE63941 | RIC3 | 79608 | 220282_at | 0.1059 | 0.5014 | |
| GSE77861 | RIC3 | 79608 | 220282_at | -0.3033 | 0.0671 | |
| GSE97050 | RIC3 | 79608 | A_24_P35537 | -0.7178 | 0.1218 | |
| SRP064894 | RIC3 | 79608 | RNAseq | -1.4680 | 0.0010 | |
| SRP133303 | RIC3 | 79608 | RNAseq | -2.2690 | 0.0000 | |
| SRP159526 | RIC3 | 79608 | RNAseq | -1.0079 | 0.0001 | |
| SRP193095 | RIC3 | 79608 | RNAseq | -0.3922 | 0.3134 | |
| SRP219564 | RIC3 | 79608 | RNAseq | -0.6078 | 0.3430 | |
| TCGA | RIC3 | 79608 | RNAseq | -1.1345 | 0.0011 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by RIC3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RIC3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RIC3 | 79608 | 0 | 11 | 19 | |
| GSE20123 | RIC3 | 79608 | 0 | 11 | 19 | |
| GSE43470 | RIC3 | 79608 | 2 | 5 | 36 | |
| GSE46452 | RIC3 | 79608 | 7 | 5 | 47 | |
| GSE47630 | RIC3 | 79608 | 2 | 12 | 26 | |
| GSE54993 | RIC3 | 79608 | 3 | 1 | 66 | |
| GSE54994 | RIC3 | 79608 | 2 | 12 | 39 | |
| GSE60625 | RIC3 | 79608 | 0 | 0 | 11 | |
| GSE74703 | RIC3 | 79608 | 1 | 4 | 31 | |
| GSE74704 | RIC3 | 79608 | 0 | 9 | 11 | |
| TCGA | RIC3 | 79608 | 9 | 36 | 51 |
Total number of gains: 26; Total number of losses: 106; Total Number of normals: 356.
Somatic mutations of RIC3:
Generating mutation plots.
Highly correlated genes for RIC3:
Showing top 20/1299 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RIC3 | ANGPTL1 | 0.813256 | 4 | 0 | 4 |
| RIC3 | C1QTNF7 | 0.806117 | 4 | 0 | 4 |
| RIC3 | RAB9B | 0.800411 | 4 | 0 | 4 |
| RIC3 | CELF2 | 0.786345 | 4 | 0 | 4 |
| RIC3 | CLEC3B | 0.784187 | 3 | 0 | 3 |
| RIC3 | AOC3 | 0.782441 | 4 | 0 | 4 |
| RIC3 | BHMT2 | 0.781866 | 4 | 0 | 4 |
| RIC3 | ADAMTS9-AS2 | 0.780035 | 3 | 0 | 3 |
| RIC3 | RBPMS2 | 0.779074 | 4 | 0 | 4 |
| RIC3 | PLN | 0.778168 | 4 | 0 | 4 |
| RIC3 | PEG3 | 0.7712 | 3 | 0 | 3 |
| RIC3 | OGN | 0.766834 | 4 | 0 | 4 |
| RIC3 | PTGIS | 0.76322 | 4 | 0 | 4 |
| RIC3 | CYP21A2 | 0.759655 | 3 | 0 | 3 |
| RIC3 | SYNPO2 | 0.758932 | 4 | 0 | 4 |
| RIC3 | PIGP | 0.757417 | 3 | 0 | 3 |
| RIC3 | RGS7BP | 0.755268 | 4 | 0 | 4 |
| RIC3 | ITPR1 | 0.755141 | 4 | 0 | 4 |
| RIC3 | CDC37L1 | 0.752027 | 4 | 0 | 4 |
| RIC3 | PI16 | 0.74707 | 4 | 0 | 4 |
For details and further investigation, click here
