| Full name: synaptopodin 2 | Alias Symbol: MYOPODIN | ||
| Type: protein-coding gene | Cytoband: 4q26 | ||
| Entrez ID: 171024 | HGNC ID: HGNC:17732 | Ensembl Gene: ENSG00000172403 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SYNPO2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYNPO2 | 171024 | 225895_at | -2.8183 | 0.1029 | |
| GSE26886 | SYNPO2 | 171024 | 227662_at | 0.0361 | 0.9732 | |
| GSE45670 | SYNPO2 | 171024 | 225895_at | -4.8157 | 0.0000 | |
| GSE53622 | SYNPO2 | 171024 | 46390 | -2.7748 | 0.0000 | |
| GSE53624 | SYNPO2 | 171024 | 46390 | -3.0107 | 0.0000 | |
| GSE63941 | SYNPO2 | 171024 | 225721_at | -4.1364 | 0.0000 | |
| GSE77861 | SYNPO2 | 171024 | 225721_at | 0.3133 | 0.2567 | |
| GSE97050 | SYNPO2 | 171024 | A_33_P3390868 | -2.9162 | 0.0620 | |
| SRP007169 | SYNPO2 | 171024 | RNAseq | -0.2042 | 0.7029 | |
| SRP008496 | SYNPO2 | 171024 | RNAseq | 1.1078 | 0.1480 | |
| SRP064894 | SYNPO2 | 171024 | RNAseq | -1.2265 | 0.0138 | |
| SRP133303 | SYNPO2 | 171024 | RNAseq | -2.9281 | 0.0000 | |
| SRP159526 | SYNPO2 | 171024 | RNAseq | -1.5866 | 0.0004 | |
| SRP193095 | SYNPO2 | 171024 | RNAseq | -1.1691 | 0.0005 | |
| SRP219564 | SYNPO2 | 171024 | RNAseq | -1.3502 | 0.2668 | |
| TCGA | SYNPO2 | 171024 | RNAseq | -0.9492 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by SYNPO2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SYNPO2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYNPO2 | 171024 | 1 | 13 | 16 | |
| GSE20123 | SYNPO2 | 171024 | 1 | 13 | 16 | |
| GSE43470 | SYNPO2 | 171024 | 0 | 13 | 30 | |
| GSE46452 | SYNPO2 | 171024 | 1 | 36 | 22 | |
| GSE47630 | SYNPO2 | 171024 | 0 | 22 | 18 | |
| GSE54993 | SYNPO2 | 171024 | 9 | 0 | 61 | |
| GSE54994 | SYNPO2 | 171024 | 1 | 10 | 42 | |
| GSE60625 | SYNPO2 | 171024 | 0 | 1 | 10 | |
| GSE74703 | SYNPO2 | 171024 | 0 | 11 | 25 | |
| GSE74704 | SYNPO2 | 171024 | 0 | 7 | 13 | |
| TCGA | SYNPO2 | 171024 | 9 | 34 | 53 |
Total number of gains: 22; Total number of losses: 160; Total Number of normals: 306.
Somatic mutations of SYNPO2:
Generating mutation plots.
Highly correlated genes for SYNPO2:
Showing top 20/1037 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYNPO2 | SLITRK3 | 0.878996 | 5 | 0 | 5 |
| SYNPO2 | ASPA | 0.857513 | 6 | 0 | 6 |
| SYNPO2 | ATP1A2 | 0.849579 | 6 | 0 | 5 |
| SYNPO2 | BHMT2 | 0.848566 | 6 | 0 | 6 |
| SYNPO2 | PDE5A | 0.847675 | 7 | 0 | 7 |
| SYNPO2 | ITGA9 | 0.845464 | 6 | 0 | 6 |
| SYNPO2 | ADAMTS8 | 0.834519 | 7 | 0 | 7 |
| SYNPO2 | FENDRR | 0.831071 | 5 | 0 | 5 |
| SYNPO2 | ANK2 | 0.830968 | 6 | 0 | 6 |
| SYNPO2 | MYOC | 0.8297 | 5 | 0 | 5 |
| SYNPO2 | PRKAR2B | 0.827697 | 8 | 0 | 8 |
| SYNPO2 | CXCL12 | 0.82621 | 6 | 0 | 6 |
| SYNPO2 | RERGL | 0.824937 | 5 | 0 | 5 |
| SYNPO2 | ARHGAP6 | 0.824067 | 6 | 0 | 6 |
| SYNPO2 | HLF | 0.822873 | 5 | 0 | 5 |
| SYNPO2 | SCN7A | 0.821995 | 7 | 0 | 6 |
| SYNPO2 | NEGR1 | 0.819064 | 6 | 0 | 6 |
| SYNPO2 | SORBS2 | 0.817634 | 5 | 0 | 5 |
| SYNPO2 | LMOD1 | 0.815176 | 9 | 0 | 8 |
| SYNPO2 | PPP1R12B | 0.815132 | 8 | 0 | 8 |
For details and further investigation, click here
