| Full name: centrobin, centriole duplication and spindle assembly protein | Alias Symbol: LIP8|PP1221 | ||
| Type: protein-coding gene | Cytoband: 17p13.1 | ||
| Entrez ID: 116840 | HGNC ID: HGNC:29616 | Ensembl Gene: ENSG00000170037 | OMIM ID: 611425 |
| Drug and gene relationship at DGIdb | |||
Expression of CNTROB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CNTROB | 116840 | 228633_s_at | 0.3166 | 0.1312 | |
| GSE26886 | CNTROB | 116840 | 228633_s_at | 0.6703 | 0.0000 | |
| GSE45670 | CNTROB | 116840 | 228633_s_at | 0.1500 | 0.1319 | |
| GSE53622 | CNTROB | 116840 | 27868 | 0.4620 | 0.0000 | |
| GSE53624 | CNTROB | 116840 | 27868 | 0.7249 | 0.0000 | |
| GSE63941 | CNTROB | 116840 | 228633_s_at | 0.6523 | 0.0012 | |
| GSE77861 | CNTROB | 116840 | 228633_s_at | 0.1498 | 0.5238 | |
| GSE97050 | CNTROB | 116840 | A_23_P9761 | 0.5248 | 0.1506 | |
| SRP007169 | CNTROB | 116840 | RNAseq | 1.6121 | 0.0052 | |
| SRP008496 | CNTROB | 116840 | RNAseq | 1.6082 | 0.0001 | |
| SRP064894 | CNTROB | 116840 | RNAseq | 1.1050 | 0.0000 | |
| SRP133303 | CNTROB | 116840 | RNAseq | 0.2924 | 0.0485 | |
| SRP159526 | CNTROB | 116840 | RNAseq | 0.7649 | 0.0679 | |
| SRP193095 | CNTROB | 116840 | RNAseq | 0.5724 | 0.0000 | |
| SRP219564 | CNTROB | 116840 | RNAseq | 0.7842 | 0.0206 | |
| TCGA | CNTROB | 116840 | RNAseq | 0.1834 | 0.0007 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by CNTROB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CNTROB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CNTROB | 116840 | 4 | 2 | 24 | |
| GSE20123 | CNTROB | 116840 | 4 | 3 | 23 | |
| GSE43470 | CNTROB | 116840 | 1 | 6 | 36 | |
| GSE46452 | CNTROB | 116840 | 34 | 1 | 24 | |
| GSE47630 | CNTROB | 116840 | 7 | 1 | 32 | |
| GSE54993 | CNTROB | 116840 | 4 | 3 | 63 | |
| GSE54994 | CNTROB | 116840 | 5 | 8 | 40 | |
| GSE60625 | CNTROB | 116840 | 4 | 0 | 7 | |
| GSE74703 | CNTROB | 116840 | 1 | 3 | 32 | |
| GSE74704 | CNTROB | 116840 | 2 | 1 | 17 | |
| TCGA | CNTROB | 116840 | 17 | 21 | 58 |
Total number of gains: 83; Total number of losses: 49; Total Number of normals: 356.
Somatic mutations of CNTROB:
Generating mutation plots.
Highly correlated genes for CNTROB:
Showing top 20/1119 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CNTROB | PFN1 | 0.840511 | 4 | 0 | 4 |
| CNTROB | RIN1 | 0.766997 | 3 | 0 | 3 |
| CNTROB | AGRN | 0.761059 | 6 | 0 | 6 |
| CNTROB | PTK7 | 0.754544 | 6 | 0 | 6 |
| CNTROB | STX1A | 0.7316 | 3 | 0 | 3 |
| CNTROB | PML | 0.730723 | 4 | 0 | 4 |
| CNTROB | NOP14 | 0.730272 | 4 | 0 | 4 |
| CNTROB | CENPI | 0.723663 | 6 | 0 | 6 |
| CNTROB | CHPF | 0.723426 | 6 | 0 | 6 |
| CNTROB | TTYH3 | 0.717596 | 6 | 0 | 6 |
| CNTROB | TMSB10 | 0.71738 | 6 | 0 | 6 |
| CNTROB | TNFSF13 | 0.712904 | 3 | 0 | 3 |
| CNTROB | FHOD1 | 0.71012 | 6 | 0 | 5 |
| CNTROB | CCDC86 | 0.707115 | 4 | 0 | 3 |
| CNTROB | GGT5 | 0.702095 | 3 | 0 | 3 |
| CNTROB | NPHP4 | 0.700113 | 5 | 0 | 5 |
| CNTROB | MFAP2 | 0.694584 | 5 | 0 | 5 |
| CNTROB | CDH3 | 0.693992 | 5 | 0 | 4 |
| CNTROB | ITGA6 | 0.693476 | 6 | 0 | 6 |
| CNTROB | PPP1R9B | 0.69266 | 4 | 0 | 3 |
For details and further investigation, click here
