| Full name: rhophilin associated tail protein 1 | Alias Symbol: ODF6|ropporin|ROPN1A|CT91 | ||
| Type: protein-coding gene | Cytoband: 3q21.1 | ||
| Entrez ID: 54763 | HGNC ID: HGNC:17692 | Ensembl Gene: ENSG00000065371 | OMIM ID: 611757 |
| Drug and gene relationship at DGIdb | |||
Expression of ROPN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ROPN1 | 54763 | 224191_x_at | -0.2290 | 0.4386 | |
| GSE26886 | ROPN1 | 54763 | 224191_x_at | 0.2531 | 0.0592 | |
| GSE45670 | ROPN1 | 54763 | 224191_x_at | -0.1616 | 0.2215 | |
| GSE53622 | ROPN1 | 54763 | 157176 | 0.5366 | 0.0000 | |
| GSE53624 | ROPN1 | 54763 | 157176 | 0.5707 | 0.0000 | |
| GSE63941 | ROPN1 | 54763 | 224191_x_at | 0.1613 | 0.5034 | |
| GSE77861 | ROPN1 | 54763 | 224191_x_at | -0.1812 | 0.1138 | |
| GSE97050 | ROPN1 | 54763 | A_32_P184464 | -0.1127 | 0.5779 | |
| SRP133303 | ROPN1 | 54763 | RNAseq | 0.3346 | 0.2633 | |
| TCGA | ROPN1 | 54763 | RNAseq | 2.4768 | 0.0132 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ROPN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ROPN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ROPN1 | 54763 | 17 | 0 | 13 | |
| GSE20123 | ROPN1 | 54763 | 17 | 0 | 13 | |
| GSE43470 | ROPN1 | 54763 | 20 | 0 | 23 | |
| GSE46452 | ROPN1 | 54763 | 14 | 5 | 40 | |
| GSE47630 | ROPN1 | 54763 | 17 | 4 | 19 | |
| GSE54993 | ROPN1 | 54763 | 2 | 7 | 61 | |
| GSE54994 | ROPN1 | 54763 | 30 | 4 | 19 | |
| GSE60625 | ROPN1 | 54763 | 0 | 6 | 5 | |
| GSE74703 | ROPN1 | 54763 | 16 | 0 | 20 | |
| GSE74704 | ROPN1 | 54763 | 13 | 0 | 7 | |
| TCGA | ROPN1 | 54763 | 54 | 6 | 36 |
Total number of gains: 200; Total number of losses: 32; Total Number of normals: 256.
Somatic mutations of ROPN1:
Generating mutation plots.
Highly correlated genes for ROPN1:
Showing top 20/92 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ROPN1 | COMMD5 | 0.75936 | 3 | 0 | 3 |
| ROPN1 | SERPINF2 | 0.755685 | 3 | 0 | 3 |
| ROPN1 | USP9Y | 0.737386 | 3 | 0 | 3 |
| ROPN1 | DNAJB7 | 0.735798 | 3 | 0 | 3 |
| ROPN1 | ERP44 | 0.730819 | 3 | 0 | 3 |
| ROPN1 | EVC2 | 0.729825 | 3 | 0 | 3 |
| ROPN1 | WDTC1 | 0.720791 | 3 | 0 | 3 |
| ROPN1 | FCHO1 | 0.717115 | 3 | 0 | 3 |
| ROPN1 | LILRB5 | 0.711757 | 4 | 0 | 4 |
| ROPN1 | GSK3A | 0.707736 | 3 | 0 | 3 |
| ROPN1 | C1GALT1C1 | 0.707436 | 3 | 0 | 3 |
| ROPN1 | DAPK3 | 0.697994 | 3 | 0 | 3 |
| ROPN1 | SLC25A29 | 0.697398 | 3 | 0 | 3 |
| ROPN1 | KRT72 | 0.688718 | 3 | 0 | 3 |
| ROPN1 | NUDT16 | 0.687941 | 3 | 0 | 3 |
| ROPN1 | PFDN1 | 0.684771 | 3 | 0 | 3 |
| ROPN1 | UTY | 0.684656 | 4 | 0 | 3 |
| ROPN1 | VAMP1 | 0.683246 | 3 | 0 | 3 |
| ROPN1 | TP53I13 | 0.678769 | 4 | 0 | 4 |
| ROPN1 | NTAN1 | 0.678581 | 3 | 0 | 3 |
For details and further investigation, click here
