| Full name: leukocyte immunoglobulin like receptor B5 | Alias Symbol: LIR-8|LIR8|CD85c | ||
| Type: protein-coding gene | Cytoband: 19q13.4 | ||
| Entrez ID: 10990 | HGNC ID: HGNC:6609 | Ensembl Gene: ENSG00000105609 | OMIM ID: 604814 |
| Drug and gene relationship at DGIdb | |||
LILRB5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04380 | Osteoclast differentiation |
Expression of LILRB5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LILRB5 | 10990 | 206856_at | -0.3463 | 0.3773 | |
| GSE20347 | LILRB5 | 10990 | 206856_at | 0.0291 | 0.7649 | |
| GSE23400 | LILRB5 | 10990 | 206856_at | -0.0594 | 0.0503 | |
| GSE26886 | LILRB5 | 10990 | 206856_at | 0.2734 | 0.0619 | |
| GSE29001 | LILRB5 | 10990 | 206856_at | 0.0460 | 0.6758 | |
| GSE38129 | LILRB5 | 10990 | 206856_at | -0.2925 | 0.0208 | |
| GSE45670 | LILRB5 | 10990 | 206856_at | -0.7537 | 0.0012 | |
| GSE53622 | LILRB5 | 10990 | 123094 | -0.1805 | 0.3583 | |
| GSE53624 | LILRB5 | 10990 | 11483 | -0.2872 | 0.2079 | |
| GSE63941 | LILRB5 | 10990 | 206856_at | 0.1218 | 0.4865 | |
| GSE77861 | LILRB5 | 10990 | 206856_at | -0.0139 | 0.8928 | |
| GSE97050 | LILRB5 | 10990 | A_23_P4773 | -0.1505 | 0.6954 | |
| SRP007169 | LILRB5 | 10990 | RNAseq | 0.9448 | 0.1745 | |
| SRP064894 | LILRB5 | 10990 | RNAseq | -0.2415 | 0.5739 | |
| SRP133303 | LILRB5 | 10990 | RNAseq | -0.4581 | 0.3075 | |
| SRP159526 | LILRB5 | 10990 | RNAseq | -0.2640 | 0.6849 | |
| SRP193095 | LILRB5 | 10990 | RNAseq | 0.0469 | 0.7627 | |
| SRP219564 | LILRB5 | 10990 | RNAseq | 0.5661 | 0.5122 | |
| TCGA | LILRB5 | 10990 | RNAseq | -0.7016 | 0.0276 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LILRB5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LILRB5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LILRB5 | 10990 | 3 | 4 | 23 | |
| GSE20123 | LILRB5 | 10990 | 3 | 3 | 24 | |
| GSE43470 | LILRB5 | 10990 | 2 | 11 | 30 | |
| GSE46452 | LILRB5 | 10990 | 45 | 1 | 13 | |
| GSE47630 | LILRB5 | 10990 | 8 | 6 | 26 | |
| GSE54993 | LILRB5 | 10990 | 17 | 4 | 49 | |
| GSE54994 | LILRB5 | 10990 | 4 | 13 | 36 | |
| GSE60625 | LILRB5 | 10990 | 9 | 0 | 2 | |
| GSE74703 | LILRB5 | 10990 | 2 | 7 | 27 | |
| GSE74704 | LILRB5 | 10990 | 3 | 1 | 16 | |
| TCGA | LILRB5 | 10990 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 65; Total Number of normals: 308.
Somatic mutations of LILRB5:
Generating mutation plots.
Highly correlated genes for LILRB5:
Showing top 20/593 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LILRB5 | GIMAP5 | 0.829928 | 3 | 0 | 3 |
| LILRB5 | TNFAIP8L2 | 0.763825 | 3 | 0 | 3 |
| LILRB5 | TNFSF12 | 0.743962 | 3 | 0 | 3 |
| LILRB5 | ARHGAP15 | 0.732908 | 3 | 0 | 3 |
| LILRB5 | DERL3 | 0.730124 | 4 | 0 | 3 |
| LILRB5 | RGS18 | 0.725795 | 4 | 0 | 3 |
| LILRB5 | DMAP1 | 0.716082 | 3 | 0 | 3 |
| LILRB5 | CCL3 | 0.713259 | 3 | 0 | 3 |
| LILRB5 | ROPN1 | 0.711757 | 4 | 0 | 4 |
| LILRB5 | LIMD2 | 0.711318 | 4 | 0 | 4 |
| LILRB5 | LCAT | 0.710092 | 4 | 0 | 4 |
| LILRB5 | CD163L1 | 0.704572 | 4 | 0 | 3 |
| LILRB5 | GAB3 | 0.702087 | 5 | 0 | 4 |
| LILRB5 | TAF6 | 0.696739 | 3 | 0 | 3 |
| LILRB5 | CD180 | 0.693933 | 6 | 0 | 6 |
| LILRB5 | TIE1 | 0.692568 | 5 | 0 | 4 |
| LILRB5 | SLIT3 | 0.692108 | 6 | 0 | 6 |
| LILRB5 | CHN2 | 0.691481 | 5 | 0 | 4 |
| LILRB5 | C19orf38 | 0.690217 | 4 | 0 | 3 |
| LILRB5 | MYO1F | 0.68953 | 5 | 0 | 4 |
For details and further investigation, click here
