| Full name: vesicle associated membrane protein 1 | Alias Symbol: VAMP-1 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 6843 | HGNC ID: HGNC:12642 | Ensembl Gene: ENSG00000139190 | OMIM ID: 185880 |
| Drug and gene relationship at DGIdb | |||
Expression of VAMP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | VAMP1 | 6843 | 213326_at | -0.9869 | 0.0900 | |
| GSE20347 | VAMP1 | 6843 | 213326_at | 0.0281 | 0.8827 | |
| GSE23400 | VAMP1 | 6843 | 213326_at | -0.0706 | 0.4561 | |
| GSE26886 | VAMP1 | 6843 | 213326_at | 0.2874 | 0.2497 | |
| GSE29001 | VAMP1 | 6843 | 213326_at | 0.0710 | 0.9020 | |
| GSE38129 | VAMP1 | 6843 | 213326_at | -0.4765 | 0.0379 | |
| GSE45670 | VAMP1 | 6843 | 213326_at | -1.0873 | 0.0000 | |
| GSE53622 | VAMP1 | 6843 | 11686 | -0.0500 | 0.7201 | |
| GSE53624 | VAMP1 | 6843 | 11686 | 0.0523 | 0.5346 | |
| GSE63941 | VAMP1 | 6843 | 213326_at | -0.6634 | 0.3875 | |
| GSE77861 | VAMP1 | 6843 | 207100_s_at | 0.0139 | 0.9250 | |
| GSE97050 | VAMP1 | 6843 | A_23_P105545 | -0.2820 | 0.2882 | |
| SRP007169 | VAMP1 | 6843 | RNAseq | 0.8665 | 0.2614 | |
| SRP064894 | VAMP1 | 6843 | RNAseq | -0.2242 | 0.3213 | |
| SRP133303 | VAMP1 | 6843 | RNAseq | -0.3583 | 0.0165 | |
| SRP159526 | VAMP1 | 6843 | RNAseq | -0.2782 | 0.2430 | |
| SRP193095 | VAMP1 | 6843 | RNAseq | 0.3671 | 0.0383 | |
| SRP219564 | VAMP1 | 6843 | RNAseq | -0.3121 | 0.3071 | |
| TCGA | VAMP1 | 6843 | RNAseq | -0.0979 | 0.2955 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by VAMP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of VAMP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | VAMP1 | 6843 | 9 | 4 | 17 | |
| GSE20123 | VAMP1 | 6843 | 9 | 4 | 17 | |
| GSE43470 | VAMP1 | 6843 | 8 | 3 | 32 | |
| GSE46452 | VAMP1 | 6843 | 10 | 1 | 48 | |
| GSE47630 | VAMP1 | 6843 | 12 | 2 | 26 | |
| GSE54993 | VAMP1 | 6843 | 1 | 10 | 59 | |
| GSE54994 | VAMP1 | 6843 | 10 | 2 | 41 | |
| GSE60625 | VAMP1 | 6843 | 0 | 1 | 10 | |
| GSE74703 | VAMP1 | 6843 | 7 | 2 | 27 | |
| GSE74704 | VAMP1 | 6843 | 5 | 3 | 12 | |
| TCGA | VAMP1 | 6843 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.
Somatic mutations of VAMP1:
Generating mutation plots.
Highly correlated genes for VAMP1:
Showing top 20/517 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| VAMP1 | LRRN4CL | 0.805602 | 3 | 0 | 3 |
| VAMP1 | IGSF10 | 0.802826 | 3 | 0 | 3 |
| VAMP1 | C11orf96 | 0.747966 | 3 | 0 | 3 |
| VAMP1 | ABI3BP | 0.745757 | 4 | 0 | 4 |
| VAMP1 | C1QTNF7 | 0.738004 | 3 | 0 | 3 |
| VAMP1 | FIBIN | 0.734767 | 3 | 0 | 3 |
| VAMP1 | MRVI1 | 0.734643 | 3 | 0 | 3 |
| VAMP1 | PCDH18 | 0.730767 | 3 | 0 | 3 |
| VAMP1 | ZNF608 | 0.727538 | 3 | 0 | 3 |
| VAMP1 | MLLT3 | 0.723749 | 3 | 0 | 3 |
| VAMP1 | RPL34 | 0.722161 | 3 | 0 | 3 |
| VAMP1 | PDE8B | 0.721136 | 3 | 0 | 3 |
| VAMP1 | MYCT1 | 0.720314 | 4 | 0 | 3 |
| VAMP1 | CYP4V2 | 0.716092 | 3 | 0 | 3 |
| VAMP1 | PCP4 | 0.714978 | 4 | 0 | 4 |
| VAMP1 | FBXL3 | 0.714769 | 3 | 0 | 3 |
| VAMP1 | RBPMS2 | 0.714122 | 3 | 0 | 3 |
| VAMP1 | ROR1 | 0.713192 | 3 | 0 | 3 |
| VAMP1 | TMEM132C | 0.707189 | 3 | 0 | 3 |
| VAMP1 | ID4 | 0.70602 | 3 | 0 | 3 |
For details and further investigation, click here
