| Full name: WD and tetratricopeptide repeats 1 | Alias Symbol: KIAA1037|ADP|DCAF9 | ||
| Type: protein-coding gene | Cytoband: 1p36.11 | ||
| Entrez ID: 23038 | HGNC ID: HGNC:29175 | Ensembl Gene: ENSG00000142784 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of WDTC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDTC1 | 23038 | 40829_at | 0.1832 | 0.6418 | |
| GSE20347 | WDTC1 | 23038 | 40829_at | -0.1344 | 0.2455 | |
| GSE23400 | WDTC1 | 23038 | 40829_at | -0.0821 | 0.0784 | |
| GSE26886 | WDTC1 | 23038 | 40829_at | 0.3045 | 0.0317 | |
| GSE29001 | WDTC1 | 23038 | 40829_at | -0.0578 | 0.8295 | |
| GSE38129 | WDTC1 | 23038 | 40829_at | -0.1541 | 0.0791 | |
| GSE45670 | WDTC1 | 23038 | 40829_at | 0.0854 | 0.3815 | |
| GSE53622 | WDTC1 | 23038 | 76141 | -0.0998 | 0.0641 | |
| GSE53624 | WDTC1 | 23038 | 76141 | 0.1436 | 0.0502 | |
| GSE63941 | WDTC1 | 23038 | 40829_at | -0.5217 | 0.0420 | |
| GSE77861 | WDTC1 | 23038 | 40829_at | -0.1298 | 0.3140 | |
| GSE97050 | WDTC1 | 23038 | A_24_P102895 | -0.0266 | 0.9564 | |
| SRP007169 | WDTC1 | 23038 | RNAseq | -0.3251 | 0.4669 | |
| SRP008496 | WDTC1 | 23038 | RNAseq | -0.7047 | 0.0175 | |
| SRP064894 | WDTC1 | 23038 | RNAseq | 0.1538 | 0.2082 | |
| SRP133303 | WDTC1 | 23038 | RNAseq | 0.0805 | 0.6847 | |
| SRP159526 | WDTC1 | 23038 | RNAseq | -0.1038 | 0.5494 | |
| SRP193095 | WDTC1 | 23038 | RNAseq | 0.0143 | 0.9122 | |
| SRP219564 | WDTC1 | 23038 | RNAseq | -0.0803 | 0.8096 | |
| TCGA | WDTC1 | 23038 | RNAseq | -0.1947 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDTC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDTC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDTC1 | 23038 | 0 | 6 | 24 | |
| GSE20123 | WDTC1 | 23038 | 0 | 5 | 25 | |
| GSE43470 | WDTC1 | 23038 | 3 | 6 | 34 | |
| GSE46452 | WDTC1 | 23038 | 5 | 1 | 53 | |
| GSE47630 | WDTC1 | 23038 | 8 | 3 | 29 | |
| GSE54993 | WDTC1 | 23038 | 2 | 1 | 67 | |
| GSE54994 | WDTC1 | 23038 | 10 | 4 | 39 | |
| GSE60625 | WDTC1 | 23038 | 0 | 0 | 11 | |
| GSE74703 | WDTC1 | 23038 | 2 | 4 | 30 | |
| GSE74704 | WDTC1 | 23038 | 0 | 0 | 20 | |
| TCGA | WDTC1 | 23038 | 10 | 24 | 62 |
Total number of gains: 40; Total number of losses: 54; Total Number of normals: 394.
Somatic mutations of WDTC1:
Generating mutation plots.
Highly correlated genes for WDTC1:
Showing top 20/525 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDTC1 | NUCB1 | 0.816847 | 3 | 0 | 3 |
| WDTC1 | UBE2O | 0.7929 | 3 | 0 | 3 |
| WDTC1 | MAP1S | 0.786683 | 3 | 0 | 3 |
| WDTC1 | CNTF | 0.780818 | 3 | 0 | 3 |
| WDTC1 | SSBP4 | 0.759283 | 3 | 0 | 3 |
| WDTC1 | ITGB3 | 0.744244 | 3 | 0 | 3 |
| WDTC1 | PRR12 | 0.738328 | 3 | 0 | 3 |
| WDTC1 | TBC1D25 | 0.737624 | 4 | 0 | 3 |
| WDTC1 | MED26 | 0.72116 | 3 | 0 | 3 |
| WDTC1 | ROPN1 | 0.720791 | 3 | 0 | 3 |
| WDTC1 | TNPO3 | 0.720156 | 3 | 0 | 3 |
| WDTC1 | STRADA | 0.713704 | 4 | 0 | 4 |
| WDTC1 | SLC29A3 | 0.713104 | 4 | 0 | 4 |
| WDTC1 | FOXC1 | 0.711179 | 3 | 0 | 3 |
| WDTC1 | SPEN | 0.708983 | 4 | 0 | 3 |
| WDTC1 | ZNF780B | 0.708752 | 3 | 0 | 3 |
| WDTC1 | C19orf54 | 0.708422 | 3 | 0 | 3 |
| WDTC1 | GRIN2D | 0.706935 | 4 | 0 | 4 |
| WDTC1 | GRWD1 | 0.705892 | 4 | 0 | 4 |
| WDTC1 | ZNF432 | 0.705826 | 3 | 0 | 3 |
For details and further investigation, click here
