| Full name: keratin 72 | Alias Symbol: K6IRS2|KRT6IRS2|KRT6|K6irs | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 140807 | HGNC ID: HGNC:28932 | Ensembl Gene: ENSG00000170486 | OMIM ID: 608246 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT72:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT72 | 140807 | 1564435_a_at | -0.2744 | 0.3334 | |
| GSE26886 | KRT72 | 140807 | 1564435_a_at | -0.1482 | 0.1638 | |
| GSE45670 | KRT72 | 140807 | 1564435_a_at | -0.0933 | 0.2243 | |
| GSE53622 | KRT72 | 140807 | 11769 | 0.0720 | 0.4649 | |
| GSE53624 | KRT72 | 140807 | 11769 | -0.0595 | 0.6723 | |
| GSE63941 | KRT72 | 140807 | 1564435_a_at | 0.0497 | 0.7841 | |
| GSE77861 | KRT72 | 140807 | 1564435_a_at | -0.1571 | 0.1309 | |
| TCGA | KRT72 | 140807 | RNAseq | 1.0649 | 0.3533 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KRT72 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT72:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT72 | 140807 | 8 | 1 | 21 | |
| GSE20123 | KRT72 | 140807 | 8 | 1 | 21 | |
| GSE43470 | KRT72 | 140807 | 3 | 0 | 40 | |
| GSE46452 | KRT72 | 140807 | 7 | 1 | 51 | |
| GSE47630 | KRT72 | 140807 | 10 | 2 | 28 | |
| GSE54993 | KRT72 | 140807 | 0 | 5 | 65 | |
| GSE54994 | KRT72 | 140807 | 5 | 1 | 47 | |
| GSE60625 | KRT72 | 140807 | 0 | 0 | 11 | |
| GSE74703 | KRT72 | 140807 | 3 | 0 | 33 | |
| GSE74704 | KRT72 | 140807 | 5 | 1 | 14 | |
| TCGA | KRT72 | 140807 | 13 | 11 | 72 |
Total number of gains: 62; Total number of losses: 23; Total Number of normals: 403.
Somatic mutations of KRT72:
Generating mutation plots.
Highly correlated genes for KRT72:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT72 | PLEKHN1 | 0.7749 | 3 | 0 | 3 |
| KRT72 | ZBTB7A | 0.700063 | 3 | 0 | 3 |
| KRT72 | CRB3 | 0.697686 | 3 | 0 | 3 |
| KRT72 | KCNT1 | 0.697248 | 3 | 0 | 3 |
| KRT72 | ROPN1 | 0.688718 | 3 | 0 | 3 |
| KRT72 | MBLAC1 | 0.687323 | 3 | 0 | 3 |
| KRT72 | OXSR1 | 0.66282 | 3 | 0 | 3 |
| KRT72 | PRR29 | 0.656346 | 3 | 0 | 3 |
| KRT72 | HCG9 | 0.655804 | 3 | 0 | 3 |
| KRT72 | GPR182 | 0.651767 | 3 | 0 | 3 |
| KRT72 | CACNB1 | 0.649694 | 3 | 0 | 3 |
| KRT72 | FAM214B | 0.649025 | 4 | 0 | 4 |
| KRT72 | KIAA1614 | 0.647414 | 4 | 0 | 4 |
| KRT72 | RAB5A | 0.645573 | 3 | 0 | 3 |
| KRT72 | LACRT | 0.641752 | 4 | 0 | 4 |
| KRT72 | TMEM79 | 0.640156 | 4 | 0 | 3 |
| KRT72 | MMD2 | 0.635696 | 3 | 0 | 3 |
| KRT72 | ZSWIM8 | 0.633318 | 3 | 0 | 3 |
| KRT72 | SLC6A18 | 0.632533 | 3 | 0 | 3 |
| KRT72 | SH3GL1 | 0.632263 | 4 | 0 | 4 |
For details and further investigation, click here
