| Full name: zinc finger CCHC-type containing 7 | Alias Symbol: FLJ22611|AIR1 | ||
| Type: protein-coding gene | Cytoband: 9p13.2 | ||
| Entrez ID: 84186 | HGNC ID: HGNC:26209 | Ensembl Gene: ENSG00000147905 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of ZCCHC7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZCCHC7 | 84186 | 226496_at | 0.0724 | 0.9269 | |
| GSE26886 | ZCCHC7 | 84186 | 226496_at | 1.2335 | 0.0000 | |
| GSE45670 | ZCCHC7 | 84186 | 226496_at | -0.1192 | 0.5622 | |
| GSE53622 | ZCCHC7 | 84186 | 44846 | 0.0007 | 0.9933 | |
| GSE53624 | ZCCHC7 | 84186 | 44846 | 0.2053 | 0.0025 | |
| GSE63941 | ZCCHC7 | 84186 | 226496_at | -0.2526 | 0.6653 | |
| GSE77861 | ZCCHC7 | 84186 | 230332_at | 0.4742 | 0.2159 | |
| GSE97050 | ZCCHC7 | 84186 | A_23_P124855 | 0.0621 | 0.7863 | |
| SRP007169 | ZCCHC7 | 84186 | RNAseq | 0.2785 | 0.6456 | |
| SRP008496 | ZCCHC7 | 84186 | RNAseq | 1.0111 | 0.0197 | |
| SRP064894 | ZCCHC7 | 84186 | RNAseq | 0.4041 | 0.0029 | |
| SRP133303 | ZCCHC7 | 84186 | RNAseq | -0.1034 | 0.5165 | |
| SRP159526 | ZCCHC7 | 84186 | RNAseq | -0.3575 | 0.1304 | |
| SRP193095 | ZCCHC7 | 84186 | RNAseq | -0.1395 | 0.3133 | |
| SRP219564 | ZCCHC7 | 84186 | RNAseq | 0.4764 | 0.1882 | |
| TCGA | ZCCHC7 | 84186 | RNAseq | 0.0533 | 0.3745 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by ZCCHC7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZCCHC7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZCCHC7 | 84186 | 3 | 13 | 14 | |
| GSE20123 | ZCCHC7 | 84186 | 3 | 13 | 14 | |
| GSE43470 | ZCCHC7 | 84186 | 1 | 12 | 30 | |
| GSE46452 | ZCCHC7 | 84186 | 6 | 15 | 38 | |
| GSE47630 | ZCCHC7 | 84186 | 1 | 20 | 19 | |
| GSE54993 | ZCCHC7 | 84186 | 6 | 0 | 64 | |
| GSE54994 | ZCCHC7 | 84186 | 5 | 13 | 35 | |
| GSE60625 | ZCCHC7 | 84186 | 0 | 0 | 11 | |
| GSE74703 | ZCCHC7 | 84186 | 1 | 8 | 27 | |
| GSE74704 | ZCCHC7 | 84186 | 0 | 10 | 10 | |
| TCGA | ZCCHC7 | 84186 | 14 | 44 | 38 |
Total number of gains: 40; Total number of losses: 148; Total Number of normals: 300.
Somatic mutations of ZCCHC7:
Generating mutation plots.
Highly correlated genes for ZCCHC7:
Showing top 20/346 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZCCHC7 | POLR1B | 0.876561 | 3 | 0 | 3 |
| ZCCHC7 | ZCCHC2 | 0.847259 | 3 | 0 | 3 |
| ZCCHC7 | GOLIM4 | 0.821852 | 3 | 0 | 3 |
| ZCCHC7 | MAP3K2 | 0.817209 | 3 | 0 | 3 |
| ZCCHC7 | PGAP1 | 0.797672 | 3 | 0 | 3 |
| ZCCHC7 | SNRPD2 | 0.785329 | 3 | 0 | 3 |
| ZCCHC7 | USPL1 | 0.780483 | 3 | 0 | 3 |
| ZCCHC7 | DHX36 | 0.77893 | 3 | 0 | 3 |
| ZCCHC7 | DDHD1 | 0.778417 | 3 | 0 | 3 |
| ZCCHC7 | ZNF397 | 0.771033 | 3 | 0 | 3 |
| ZCCHC7 | RPL7L1 | 0.771015 | 3 | 0 | 3 |
| ZCCHC7 | LARP6 | 0.767088 | 3 | 0 | 3 |
| ZCCHC7 | GLA | 0.758514 | 3 | 0 | 3 |
| ZCCHC7 | MORC2 | 0.756329 | 3 | 0 | 3 |
| ZCCHC7 | TCF7L2 | 0.756017 | 3 | 0 | 3 |
| ZCCHC7 | PELI2 | 0.755553 | 3 | 0 | 3 |
| ZCCHC7 | WDR75 | 0.755126 | 3 | 0 | 3 |
| ZCCHC7 | PAICS | 0.753401 | 3 | 0 | 3 |
| ZCCHC7 | SLC39A14 | 0.752333 | 3 | 0 | 3 |
| ZCCHC7 | INHBB | 0.749102 | 3 | 0 | 3 |
For details and further investigation, click here
