| Full name: DnaJ heat shock protein family (Hsp40) member C1 | Alias Symbol: DNAJL1|ERdj1|MTJ1 | ||
| Type: protein-coding gene | Cytoband: 10p12.31 | ||
| Entrez ID: 64215 | HGNC ID: HGNC:20090 | Ensembl Gene: ENSG00000136770 | OMIM ID: 611207 |
| Drug and gene relationship at DGIdb | |||
Expression of DNAJC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DNAJC1 | 64215 | 222620_s_at | -0.3253 | 0.3717 | |
| GSE20347 | DNAJC1 | 64215 | 218409_s_at | -0.5554 | 0.0000 | |
| GSE23400 | DNAJC1 | 64215 | 218409_s_at | -0.2583 | 0.0000 | |
| GSE26886 | DNAJC1 | 64215 | 222620_s_at | -0.4439 | 0.0156 | |
| GSE29001 | DNAJC1 | 64215 | 218409_s_at | -0.3077 | 0.2023 | |
| GSE38129 | DNAJC1 | 64215 | 218409_s_at | -0.3752 | 0.0026 | |
| GSE45670 | DNAJC1 | 64215 | 222620_s_at | -0.1604 | 0.3288 | |
| GSE53622 | DNAJC1 | 64215 | 92847 | -0.4281 | 0.0000 | |
| GSE53624 | DNAJC1 | 64215 | 120783 | -0.3529 | 0.0000 | |
| GSE63941 | DNAJC1 | 64215 | 222620_s_at | 0.2458 | 0.5398 | |
| GSE77861 | DNAJC1 | 64215 | 222620_s_at | -0.2625 | 0.4834 | |
| GSE97050 | DNAJC1 | 64215 | A_33_P3290687 | -0.0131 | 0.9751 | |
| SRP007169 | DNAJC1 | 64215 | RNAseq | -0.5256 | 0.1401 | |
| SRP008496 | DNAJC1 | 64215 | RNAseq | -0.6182 | 0.0099 | |
| SRP064894 | DNAJC1 | 64215 | RNAseq | 0.0073 | 0.9754 | |
| SRP133303 | DNAJC1 | 64215 | RNAseq | -0.0950 | 0.4960 | |
| SRP159526 | DNAJC1 | 64215 | RNAseq | -0.3763 | 0.3144 | |
| SRP193095 | DNAJC1 | 64215 | RNAseq | -0.3412 | 0.0418 | |
| SRP219564 | DNAJC1 | 64215 | RNAseq | -0.2155 | 0.4054 | |
| TCGA | DNAJC1 | 64215 | RNAseq | -0.2263 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DNAJC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DNAJC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DNAJC1 | 64215 | 5 | 8 | 17 | |
| GSE20123 | DNAJC1 | 64215 | 5 | 7 | 18 | |
| GSE43470 | DNAJC1 | 64215 | 4 | 4 | 35 | |
| GSE46452 | DNAJC1 | 64215 | 1 | 14 | 44 | |
| GSE47630 | DNAJC1 | 64215 | 5 | 15 | 20 | |
| GSE54993 | DNAJC1 | 64215 | 11 | 0 | 59 | |
| GSE54994 | DNAJC1 | 64215 | 3 | 9 | 41 | |
| GSE60625 | DNAJC1 | 64215 | 0 | 0 | 11 | |
| GSE74703 | DNAJC1 | 64215 | 3 | 2 | 31 | |
| GSE74704 | DNAJC1 | 64215 | 0 | 6 | 14 | |
| TCGA | DNAJC1 | 64215 | 17 | 26 | 53 |
Total number of gains: 54; Total number of losses: 91; Total Number of normals: 343.
Somatic mutations of DNAJC1:
Generating mutation plots.
Highly correlated genes for DNAJC1:
Showing top 20/607 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DNAJC1 | MRPS31 | 0.786478 | 3 | 0 | 3 |
| DNAJC1 | EIF2S2 | 0.769492 | 3 | 0 | 3 |
| DNAJC1 | PAIP2 | 0.750704 | 3 | 0 | 3 |
| DNAJC1 | MBNL3 | 0.748441 | 3 | 0 | 3 |
| DNAJC1 | IFT74 | 0.724283 | 4 | 0 | 3 |
| DNAJC1 | HDHD2 | 0.723295 | 3 | 0 | 3 |
| DNAJC1 | TK2 | 0.719957 | 3 | 0 | 3 |
| DNAJC1 | CLDND1 | 0.712354 | 3 | 0 | 3 |
| DNAJC1 | RNGTT | 0.711904 | 3 | 0 | 3 |
| DNAJC1 | RGS14 | 0.70072 | 3 | 0 | 3 |
| DNAJC1 | AP3M1 | 0.696419 | 3 | 0 | 3 |
| DNAJC1 | ME3 | 0.695887 | 4 | 0 | 4 |
| DNAJC1 | ARMCX5 | 0.693098 | 3 | 0 | 3 |
| DNAJC1 | FNDC3A | 0.682253 | 4 | 0 | 4 |
| DNAJC1 | PLA2G12A | 0.682156 | 6 | 0 | 5 |
| DNAJC1 | GIMAP1 | 0.681893 | 3 | 0 | 3 |
| DNAJC1 | FAM122C | 0.680442 | 3 | 0 | 3 |
| DNAJC1 | LIPT1 | 0.674416 | 4 | 0 | 3 |
| DNAJC1 | SLITRK6 | 0.671608 | 3 | 0 | 3 |
| DNAJC1 | CD47 | 0.669883 | 4 | 0 | 3 |
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