RAB20

 

Full name: RAB20, member RAS oncogene family Alias Symbol: FLJ20429
Type: protein-coding gene Cytoband: 13q34
Entrez ID: 55647 HGNC ID: HGNC:18260 Ensembl Gene: ENSG00000139832 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of RAB20:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 RAB20 55647 219622_at -0.0031 0.9973
GSE20347 RAB20 55647 219622_at 0.7692 0.0035
GSE23400 RAB20 55647 219622_at 0.0986 0.0650
GSE26886 RAB20 55647 219622_at 1.6304 0.0000
GSE29001 RAB20 55647 219622_at 0.7800 0.0019
GSE38129 RAB20 55647 219622_at 0.5609 0.0374
GSE45670 RAB20 55647 219622_at 0.0337 0.9261
GSE53622 RAB20 55647 61625 0.7112 0.0000
GSE53624 RAB20 55647 61625 0.7076 0.0000
GSE63941 RAB20 55647 219622_at 1.4089 0.0514
GSE77861 RAB20 55647 219622_at 0.3520 0.1209
GSE97050 RAB20 55647 A_24_P22050 0.3556 0.3701
SRP007169 RAB20 55647 RNAseq 3.2540 0.0002
SRP064894 RAB20 55647 RNAseq 1.0745 0.0004
SRP133303 RAB20 55647 RNAseq 1.0242 0.0000
SRP159526 RAB20 55647 RNAseq 0.4707 0.2989
SRP193095 RAB20 55647 RNAseq 0.0112 0.9802
SRP219564 RAB20 55647 RNAseq 1.3476 0.0224
TCGA RAB20 55647 RNAseq -0.5731 0.0000

Upregulated datasets: 5; Downregulated datasets: 0.  


 

Survival by RAB20 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of RAB20:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RAB20 55647 6 11 13
GSE20123 RAB20 55647 6 10 14
GSE43470 RAB20 55647 4 13 26
GSE46452 RAB20 55647 2 31 26
GSE47630 RAB20 55647 3 26 11
GSE54993 RAB20 55647 11 4 55
GSE54994 RAB20 55647 8 8 37
GSE60625 RAB20 55647 0 3 8
GSE74703 RAB20 55647 3 9 24
GSE74704 RAB20 55647 4 9 7
TCGA RAB20 55647 19 33 44

Total number of gains: 66; Total number of losses: 157; Total Number of normals: 265.  


 

Somatic mutations of RAB20:

 

Generating mutation plots.

 

Highly correlated genes for RAB20:

 

Showing top 20/886 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RAB20SORBS30.732531303
RAB20KDM6B0.72512303
RAB20ECSIT0.72264303
RAB20DDX60L0.719933303
RAB20CIC0.705279303
RAB20CHD30.699647303
RAB20SNRPD20.695479303
RAB20STAT20.691454303
RAB20DOCK110.688319504
RAB20BLACAT10.680156403
RAB20SSBP40.679611403
RAB20NRM0.676915505
RAB20C30.671872404
RAB20CXCL160.670897404
RAB20MIER20.670683303
RAB20PET1170.669663303
RAB20TBX10.669049303
RAB20ASB70.66795303
RAB20TES0.666399403
RAB20CDON0.666103303

For details and further investigation, click here