| Full name: ribosomal protein S27 | Alias Symbol: MPS-1|MPS1|S27 | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6232 | HGNC ID: HGNC:10416 | Ensembl Gene: ENSG00000177954 | OMIM ID: 603702 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS27 | 6232 | 200741_s_at | -0.0361 | 0.8797 | |
| GSE20347 | RPS27 | 6232 | 200741_s_at | 0.1233 | 0.0472 | |
| GSE23400 | RPS27 | 6232 | 200741_s_at | 0.0865 | 0.0586 | |
| GSE26886 | RPS27 | 6232 | 200741_s_at | 0.5061 | 0.0012 | |
| GSE29001 | RPS27 | 6232 | 200741_s_at | -0.0405 | 0.8862 | |
| GSE38129 | RPS27 | 6232 | 200741_s_at | 0.0434 | 0.4762 | |
| GSE45670 | RPS27 | 6232 | 200741_s_at | -0.1739 | 0.0091 | |
| GSE53622 | RPS27 | 6232 | 14126 | 0.0187 | 0.8139 | |
| GSE53624 | RPS27 | 6232 | 14126 | 0.0977 | 0.1309 | |
| GSE63941 | RPS27 | 6232 | 200741_s_at | 0.4301 | 0.0140 | |
| GSE77861 | RPS27 | 6232 | 200741_s_at | 0.0582 | 0.5199 | |
| GSE97050 | RPS27 | 6232 | A_24_P148235 | -0.0657 | 0.8494 | |
| SRP007169 | RPS27 | 6232 | RNAseq | -0.7666 | 0.0304 | |
| SRP008496 | RPS27 | 6232 | RNAseq | -0.3201 | 0.2709 | |
| SRP064894 | RPS27 | 6232 | RNAseq | -0.3474 | 0.3602 | |
| SRP133303 | RPS27 | 6232 | RNAseq | -0.3348 | 0.1358 | |
| SRP159526 | RPS27 | 6232 | RNAseq | -0.2812 | 0.4332 | |
| SRP193095 | RPS27 | 6232 | RNAseq | -0.8446 | 0.0000 | |
| SRP219564 | RPS27 | 6232 | RNAseq | -0.5462 | 0.0109 | |
| TCGA | RPS27 | 6232 | RNAseq | 0.1198 | 0.3585 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPS27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS27 | 6232 | 14 | 0 | 16 | |
| GSE20123 | RPS27 | 6232 | 14 | 0 | 16 | |
| GSE43470 | RPS27 | 6232 | 7 | 2 | 34 | |
| GSE46452 | RPS27 | 6232 | 2 | 1 | 56 | |
| GSE47630 | RPS27 | 6232 | 14 | 0 | 26 | |
| GSE54993 | RPS27 | 6232 | 0 | 4 | 66 | |
| GSE54994 | RPS27 | 6232 | 16 | 0 | 37 | |
| GSE60625 | RPS27 | 6232 | 0 | 0 | 11 | |
| GSE74703 | RPS27 | 6232 | 6 | 1 | 29 | |
| GSE74704 | RPS27 | 6232 | 7 | 0 | 13 | |
| TCGA | RPS27 | 6232 | 38 | 2 | 56 |
Total number of gains: 118; Total number of losses: 10; Total Number of normals: 360.
Somatic mutations of RPS27:
Generating mutation plots.
Highly correlated genes for RPS27:
Showing top 20/509 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS27 | NDUFB4 | 0.766143 | 4 | 0 | 4 |
| RPS27 | CAMTA1 | 0.744306 | 3 | 0 | 3 |
| RPS27 | SCMH1 | 0.742164 | 3 | 0 | 3 |
| RPS27 | UEVLD | 0.741867 | 3 | 0 | 3 |
| RPS27 | ZNF691 | 0.735432 | 3 | 0 | 3 |
| RPS27 | KRTCAP2 | 0.73333 | 3 | 0 | 3 |
| RPS27 | ZNRF3 | 0.729768 | 3 | 0 | 3 |
| RPS27 | LRCH3 | 0.727895 | 3 | 0 | 3 |
| RPS27 | RCSD1 | 0.716719 | 3 | 0 | 3 |
| RPS27 | COPS3 | 0.71635 | 3 | 0 | 3 |
| RPS27 | COX20 | 0.714669 | 3 | 0 | 3 |
| RPS27 | DFFA | 0.712857 | 3 | 0 | 3 |
| RPS27 | RPL4 | 0.707658 | 3 | 0 | 3 |
| RPS27 | TTC7B | 0.707558 | 3 | 0 | 3 |
| RPS27 | HES4 | 0.704769 | 3 | 0 | 3 |
| RPS27 | PRTFDC1 | 0.699611 | 3 | 0 | 3 |
| RPS27 | FAR2 | 0.69819 | 3 | 0 | 3 |
| RPS27 | DCUN1D4 | 0.697175 | 4 | 0 | 4 |
| RPS27 | SYNE2 | 0.695652 | 4 | 0 | 4 |
| RPS27 | TRAP1 | 0.695558 | 3 | 0 | 3 |
For details and further investigation, click here
