| Full name: iduronate 2-sulfatase | Alias Symbol: ID2S | ||
| Type: protein-coding gene | Cytoband: Xq28 | ||
| Entrez ID: 3423 | HGNC ID: HGNC:5389 | Ensembl Gene: ENSG00000010404 | OMIM ID: 300823 |
| Drug and gene relationship at DGIdb | |||
Expression of IDS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IDS | 3423 | 212221_x_at | -0.5154 | 0.3168 | |
| GSE20347 | IDS | 3423 | 212221_x_at | 0.1501 | 0.4078 | |
| GSE23400 | IDS | 3423 | 212221_x_at | -0.0387 | 0.7267 | |
| GSE26886 | IDS | 3423 | 212221_x_at | 1.0597 | 0.0000 | |
| GSE29001 | IDS | 3423 | 212221_x_at | -0.2410 | 0.3616 | |
| GSE38129 | IDS | 3423 | 212221_x_at | -0.0439 | 0.8272 | |
| GSE45670 | IDS | 3423 | 212221_x_at | -0.1092 | 0.5626 | |
| GSE53622 | IDS | 3423 | 14355 | -0.0303 | 0.6977 | |
| GSE53624 | IDS | 3423 | 14355 | -0.4419 | 0.0000 | |
| GSE63941 | IDS | 3423 | 212221_x_at | -0.6145 | 0.3734 | |
| GSE77861 | IDS | 3423 | 212221_x_at | 0.6594 | 0.0485 | |
| GSE97050 | IDS | 3423 | A_24_P285032 | 0.2958 | 0.3684 | |
| SRP007169 | IDS | 3423 | RNAseq | -1.3016 | 0.0162 | |
| SRP008496 | IDS | 3423 | RNAseq | -1.0563 | 0.0003 | |
| SRP064894 | IDS | 3423 | RNAseq | -0.7588 | 0.0000 | |
| SRP133303 | IDS | 3423 | RNAseq | 0.3232 | 0.1556 | |
| SRP159526 | IDS | 3423 | RNAseq | -0.6212 | 0.1522 | |
| SRP193095 | IDS | 3423 | RNAseq | -0.1139 | 0.3975 | |
| SRP219564 | IDS | 3423 | RNAseq | -0.3203 | 0.4252 | |
| TCGA | IDS | 3423 | RNAseq | -0.0421 | 0.4799 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by IDS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IDS:
No record found for this gene.
Somatic mutations of IDS:
Generating mutation plots.
Highly correlated genes for IDS:
Showing top 20/685 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IDS | BRI3 | 0.835263 | 3 | 0 | 3 |
| IDS | SP4 | 0.808914 | 3 | 0 | 3 |
| IDS | KIAA1324L | 0.807635 | 3 | 0 | 3 |
| IDS | TRIM47 | 0.805206 | 3 | 0 | 3 |
| IDS | SLC41A1 | 0.799838 | 3 | 0 | 3 |
| IDS | SEL1L3 | 0.794347 | 3 | 0 | 3 |
| IDS | ATF2 | 0.793975 | 3 | 0 | 3 |
| IDS | TAF6 | 0.776783 | 3 | 0 | 3 |
| IDS | XPR1 | 0.77387 | 3 | 0 | 3 |
| IDS | SP100 | 0.770811 | 3 | 0 | 3 |
| IDS | ADCY3 | 0.769227 | 3 | 0 | 3 |
| IDS | B3GNT9 | 0.767351 | 3 | 0 | 3 |
| IDS | LIN7A | 0.755065 | 3 | 0 | 3 |
| IDS | ZNF414 | 0.746319 | 3 | 0 | 3 |
| IDS | CPNE2 | 0.744762 | 3 | 0 | 3 |
| IDS | COMMD6 | 0.742538 | 3 | 0 | 3 |
| IDS | PTGFRN | 0.738837 | 3 | 0 | 3 |
| IDS | AKR1B1 | 0.734701 | 3 | 0 | 3 |
| IDS | BCAS4 | 0.734516 | 3 | 0 | 3 |
| IDS | GNPAT | 0.72894 | 3 | 0 | 3 |
For details and further investigation, click here
