| Full name: sorting nexin 7 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1p21.3 | ||
| Entrez ID: 51375 | HGNC ID: HGNC:14971 | Ensembl Gene: ENSG00000162627 | OMIM ID: 614904 |
| Drug and gene relationship at DGIdb | |||
Expression of SNX7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNX7 | 51375 | 205573_s_at | -0.3522 | 0.6037 | |
| GSE20347 | SNX7 | 51375 | 205573_s_at | -1.0041 | 0.0139 | |
| GSE23400 | SNX7 | 51375 | 205573_s_at | 0.0506 | 0.6859 | |
| GSE26886 | SNX7 | 51375 | 205573_s_at | -0.6136 | 0.0374 | |
| GSE29001 | SNX7 | 51375 | 205573_s_at | -0.3191 | 0.5873 | |
| GSE38129 | SNX7 | 51375 | 205573_s_at | -0.5952 | 0.0475 | |
| GSE45670 | SNX7 | 51375 | 205573_s_at | -0.2073 | 0.4847 | |
| GSE53622 | SNX7 | 51375 | 94299 | -0.3752 | 0.0002 | |
| GSE53624 | SNX7 | 51375 | 94299 | -0.3148 | 0.0172 | |
| GSE63941 | SNX7 | 51375 | 205573_s_at | -0.4203 | 0.6939 | |
| GSE77861 | SNX7 | 51375 | 205573_s_at | -0.5503 | 0.2784 | |
| GSE97050 | SNX7 | 51375 | A_23_P35066 | -0.0857 | 0.8138 | |
| SRP007169 | SNX7 | 51375 | RNAseq | -1.0876 | 0.0466 | |
| SRP008496 | SNX7 | 51375 | RNAseq | -0.5741 | 0.0882 | |
| SRP064894 | SNX7 | 51375 | RNAseq | 0.3670 | 0.1152 | |
| SRP133303 | SNX7 | 51375 | RNAseq | 0.2983 | 0.2205 | |
| SRP159526 | SNX7 | 51375 | RNAseq | -0.9056 | 0.0028 | |
| SRP193095 | SNX7 | 51375 | RNAseq | -0.5731 | 0.0014 | |
| SRP219564 | SNX7 | 51375 | RNAseq | -0.1778 | 0.7499 | |
| TCGA | SNX7 | 51375 | RNAseq | -0.0936 | 0.2220 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SNX7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNX7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNX7 | 51375 | 0 | 9 | 21 | |
| GSE20123 | SNX7 | 51375 | 0 | 9 | 21 | |
| GSE43470 | SNX7 | 51375 | 2 | 5 | 36 | |
| GSE46452 | SNX7 | 51375 | 1 | 1 | 57 | |
| GSE47630 | SNX7 | 51375 | 9 | 5 | 26 | |
| GSE54993 | SNX7 | 51375 | 0 | 1 | 69 | |
| GSE54994 | SNX7 | 51375 | 6 | 3 | 44 | |
| GSE60625 | SNX7 | 51375 | 0 | 0 | 11 | |
| GSE74703 | SNX7 | 51375 | 1 | 4 | 31 | |
| GSE74704 | SNX7 | 51375 | 0 | 5 | 15 | |
| TCGA | SNX7 | 51375 | 6 | 23 | 67 |
Total number of gains: 25; Total number of losses: 65; Total Number of normals: 398.
Somatic mutations of SNX7:
Generating mutation plots.
Highly correlated genes for SNX7:
Showing top 20/603 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNX7 | SAMD8 | 0.761889 | 3 | 0 | 3 |
| SNX7 | CLEC14A | 0.722887 | 3 | 0 | 3 |
| SNX7 | DSEL | 0.718165 | 3 | 0 | 3 |
| SNX7 | COX5A | 0.711358 | 3 | 0 | 3 |
| SNX7 | PXK | 0.708452 | 3 | 0 | 3 |
| SNX7 | FYTTD1 | 0.696464 | 3 | 0 | 3 |
| SNX7 | PCDH18 | 0.696269 | 3 | 0 | 3 |
| SNX7 | DOCK7 | 0.696068 | 5 | 0 | 5 |
| SNX7 | ZNF627 | 0.695931 | 3 | 0 | 3 |
| SNX7 | RPL27 | 0.693113 | 3 | 0 | 3 |
| SNX7 | BBS12 | 0.690259 | 4 | 0 | 3 |
| SNX7 | IRF8 | 0.686461 | 3 | 0 | 3 |
| SNX7 | DNAJC24 | 0.686438 | 4 | 0 | 4 |
| SNX7 | TRIM32 | 0.685363 | 3 | 0 | 3 |
| SNX7 | FECH | 0.684404 | 3 | 0 | 3 |
| SNX7 | MAN1A2 | 0.681251 | 4 | 0 | 3 |
| SNX7 | ASCC1 | 0.676304 | 4 | 0 | 4 |
| SNX7 | ARRDC4 | 0.672969 | 3 | 0 | 3 |
| SNX7 | GLRX3 | 0.672496 | 4 | 0 | 3 |
| SNX7 | PPIL3 | 0.671646 | 4 | 0 | 3 |
For details and further investigation, click here
