| Full name: eukaryotic translation initiation factor 3 subunit M | Alias Symbol: hfl-B5|FLJ29030|GA17|eIF3m|TANGO7 | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 10480 | HGNC ID: HGNC:24460 | Ensembl Gene: ENSG00000149100 | OMIM ID: 609641 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of EIF3M:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF3M | 10480 | 202231_at | -0.1627 | 0.7449 | |
| GSE20347 | EIF3M | 10480 | 202231_at | -0.3501 | 0.0032 | |
| GSE23400 | EIF3M | 10480 | 202231_at | 0.1834 | 0.0253 | |
| GSE26886 | EIF3M | 10480 | 202231_at | 0.6316 | 0.0001 | |
| GSE29001 | EIF3M | 10480 | 202231_at | -0.0199 | 0.9512 | |
| GSE38129 | EIF3M | 10480 | 202231_at | -0.1506 | 0.1714 | |
| GSE45670 | EIF3M | 10480 | 202231_at | 0.0272 | 0.8337 | |
| GSE63941 | EIF3M | 10480 | 202231_at | 0.5489 | 0.0168 | |
| GSE77861 | EIF3M | 10480 | 202231_at | -0.0639 | 0.8329 | |
| GSE97050 | EIF3M | 10480 | A_24_P138361 | 0.0493 | 0.9200 | |
| SRP007169 | EIF3M | 10480 | RNAseq | -0.4101 | 0.2463 | |
| SRP008496 | EIF3M | 10480 | RNAseq | -0.3513 | 0.1125 | |
| SRP064894 | EIF3M | 10480 | RNAseq | -0.1087 | 0.4875 | |
| SRP133303 | EIF3M | 10480 | RNAseq | 0.1720 | 0.3768 | |
| SRP159526 | EIF3M | 10480 | RNAseq | -0.5405 | 0.1086 | |
| SRP193095 | EIF3M | 10480 | RNAseq | -0.5675 | 0.0000 | |
| SRP219564 | EIF3M | 10480 | RNAseq | -0.1050 | 0.6408 | |
| TCGA | EIF3M | 10480 | RNAseq | 0.0881 | 0.1109 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by EIF3M expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EIF3M:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF3M | 10480 | 1 | 8 | 21 | |
| GSE20123 | EIF3M | 10480 | 1 | 7 | 22 | |
| GSE43470 | EIF3M | 10480 | 4 | 4 | 35 | |
| GSE46452 | EIF3M | 10480 | 8 | 5 | 46 | |
| GSE47630 | EIF3M | 10480 | 3 | 10 | 27 | |
| GSE54993 | EIF3M | 10480 | 3 | 0 | 67 | |
| GSE54994 | EIF3M | 10480 | 3 | 10 | 40 | |
| GSE60625 | EIF3M | 10480 | 0 | 0 | 11 | |
| GSE74703 | EIF3M | 10480 | 3 | 2 | 31 | |
| GSE74704 | EIF3M | 10480 | 0 | 6 | 14 | |
| TCGA | EIF3M | 10480 | 12 | 24 | 60 |
Total number of gains: 38; Total number of losses: 76; Total Number of normals: 374.
Somatic mutations of EIF3M:
Generating mutation plots.
Highly correlated genes for EIF3M:
Showing top 20/351 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF3M | MATR3 | 0.795078 | 3 | 0 | 3 |
| EIF3M | HIPK3 | 0.794514 | 3 | 0 | 3 |
| EIF3M | CD47 | 0.786104 | 3 | 0 | 3 |
| EIF3M | MAP3K2 | 0.77376 | 3 | 0 | 3 |
| EIF3M | INTS4 | 0.773086 | 3 | 0 | 3 |
| EIF3M | NOL10 | 0.767507 | 3 | 0 | 3 |
| EIF3M | MRPL47 | 0.762148 | 3 | 0 | 3 |
| EIF3M | ZNF557 | 0.761332 | 3 | 0 | 3 |
| EIF3M | MARK1 | 0.737121 | 3 | 0 | 3 |
| EIF3M | ANAPC4 | 0.736121 | 3 | 0 | 3 |
| EIF3M | TPP2 | 0.732506 | 3 | 0 | 3 |
| EIF3M | ATF2 | 0.729234 | 3 | 0 | 3 |
| EIF3M | RPL27 | 0.724392 | 3 | 0 | 3 |
| EIF3M | SFR1 | 0.722821 | 3 | 0 | 3 |
| EIF3M | AIMP1 | 0.721683 | 5 | 0 | 5 |
| EIF3M | RNASEH2C | 0.715585 | 3 | 0 | 3 |
| EIF3M | RNF13 | 0.713201 | 3 | 0 | 3 |
| EIF3M | NAIP | 0.712805 | 3 | 0 | 3 |
| EIF3M | RIOK1 | 0.71088 | 3 | 0 | 3 |
| EIF3M | EIF1B | 0.708659 | 4 | 0 | 4 |
For details and further investigation, click here
