| Full name: transmembrane protein 126A | Alias Symbol: DKFZp586C1924|OPA7 | ||
| Type: protein-coding gene | Cytoband: 11q14.1 | ||
| Entrez ID: 84233 | HGNC ID: HGNC:25382 | Ensembl Gene: ENSG00000171202 | OMIM ID: 612988 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM126A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM126A | 84233 | 223334_at | -0.3605 | 0.3815 | |
| GSE26886 | TMEM126A | 84233 | 223334_at | -0.5311 | 0.0361 | |
| GSE45670 | TMEM126A | 84233 | 223334_at | -0.1191 | 0.4659 | |
| GSE53622 | TMEM126A | 84233 | 24887 | -0.1666 | 0.0238 | |
| GSE53624 | TMEM126A | 84233 | 24887 | -0.0828 | 0.3080 | |
| GSE63941 | TMEM126A | 84233 | 223334_at | -0.0598 | 0.9046 | |
| GSE77861 | TMEM126A | 84233 | 223334_at | -0.7048 | 0.1383 | |
| GSE97050 | TMEM126A | 84233 | A_23_P13524 | 0.0284 | 0.9503 | |
| SRP007169 | TMEM126A | 84233 | RNAseq | -0.5188 | 0.2441 | |
| SRP008496 | TMEM126A | 84233 | RNAseq | -0.5258 | 0.0682 | |
| SRP064894 | TMEM126A | 84233 | RNAseq | -0.0170 | 0.9495 | |
| SRP133303 | TMEM126A | 84233 | RNAseq | -0.3694 | 0.0391 | |
| SRP159526 | TMEM126A | 84233 | RNAseq | -0.7209 | 0.0164 | |
| SRP193095 | TMEM126A | 84233 | RNAseq | -0.9110 | 0.0000 | |
| SRP219564 | TMEM126A | 84233 | RNAseq | -0.3673 | 0.2097 | |
| TCGA | TMEM126A | 84233 | RNAseq | -0.1765 | 0.0212 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TMEM126A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM126A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM126A | 84233 | 4 | 9 | 17 | |
| GSE20123 | TMEM126A | 84233 | 4 | 9 | 17 | |
| GSE43470 | TMEM126A | 84233 | 3 | 4 | 36 | |
| GSE46452 | TMEM126A | 84233 | 6 | 24 | 29 | |
| GSE47630 | TMEM126A | 84233 | 2 | 19 | 19 | |
| GSE54993 | TMEM126A | 84233 | 8 | 2 | 60 | |
| GSE54994 | TMEM126A | 84233 | 5 | 19 | 29 | |
| GSE60625 | TMEM126A | 84233 | 0 | 3 | 8 | |
| GSE74703 | TMEM126A | 84233 | 2 | 3 | 31 | |
| GSE74704 | TMEM126A | 84233 | 3 | 6 | 11 | |
| TCGA | TMEM126A | 84233 | 16 | 38 | 42 |
Total number of gains: 53; Total number of losses: 136; Total Number of normals: 299.
Somatic mutations of TMEM126A:
Generating mutation plots.
Highly correlated genes for TMEM126A:
Showing top 20/503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM126A | SARNP | 0.830249 | 3 | 0 | 3 |
| TMEM126A | DCAF10 | 0.805279 | 3 | 0 | 3 |
| TMEM126A | RNLS | 0.778893 | 3 | 0 | 3 |
| TMEM126A | ESYT2 | 0.768546 | 3 | 0 | 3 |
| TMEM126A | TRAPPC6B | 0.765141 | 3 | 0 | 3 |
| TMEM126A | RPL37A | 0.757743 | 3 | 0 | 3 |
| TMEM126A | ATG2B | 0.752903 | 3 | 0 | 3 |
| TMEM126A | BTRC | 0.74672 | 3 | 0 | 3 |
| TMEM126A | NDUFS4 | 0.744758 | 3 | 0 | 3 |
| TMEM126A | NIPAL3 | 0.744347 | 3 | 0 | 3 |
| TMEM126A | MBNL3 | 0.7427 | 3 | 0 | 3 |
| TMEM126A | C12orf29 | 0.740188 | 4 | 0 | 4 |
| TMEM126A | BARD1 | 0.738638 | 3 | 0 | 3 |
| TMEM126A | MKRN2 | 0.737821 | 4 | 0 | 4 |
| TMEM126A | IDE | 0.737514 | 4 | 0 | 4 |
| TMEM126A | NDUFB8 | 0.732624 | 3 | 0 | 3 |
| TMEM126A | GLUD2 | 0.73212 | 3 | 0 | 3 |
| TMEM126A | MRPS11 | 0.730408 | 3 | 0 | 3 |
| TMEM126A | SACM1L | 0.729644 | 5 | 0 | 5 |
| TMEM126A | TRA2A | 0.729081 | 3 | 0 | 3 |
For details and further investigation, click here
