| Full name: ADP ribosylation factor GTPase activating protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 26286 | HGNC ID: HGNC:661 | Ensembl Gene: ENSG00000242247 | OMIM ID: 612439 |
| Drug and gene relationship at DGIdb | |||
Expression of ARFGAP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ARFGAP3 | 26286 | 202211_at | 0.0747 | 0.8483 | |
| GSE20347 | ARFGAP3 | 26286 | 202211_at | 0.2712 | 0.0923 | |
| GSE23400 | ARFGAP3 | 26286 | 202211_at | 0.4248 | 0.0000 | |
| GSE26886 | ARFGAP3 | 26286 | 202211_at | 0.7522 | 0.0008 | |
| GSE29001 | ARFGAP3 | 26286 | 202211_at | 0.3565 | 0.2821 | |
| GSE38129 | ARFGAP3 | 26286 | 202211_at | 0.2805 | 0.0995 | |
| GSE45670 | ARFGAP3 | 26286 | 202211_at | 0.3361 | 0.1331 | |
| GSE53622 | ARFGAP3 | 26286 | 52687 | 0.4047 | 0.0000 | |
| GSE53624 | ARFGAP3 | 26286 | 52687 | 0.4392 | 0.0000 | |
| GSE63941 | ARFGAP3 | 26286 | 202211_at | -1.0229 | 0.0978 | |
| GSE77861 | ARFGAP3 | 26286 | 202211_at | 0.3556 | 0.1539 | |
| GSE97050 | ARFGAP3 | 26286 | A_23_P68970 | 0.5391 | 0.1140 | |
| SRP007169 | ARFGAP3 | 26286 | RNAseq | 0.4630 | 0.1238 | |
| SRP008496 | ARFGAP3 | 26286 | RNAseq | 0.3887 | 0.0137 | |
| SRP064894 | ARFGAP3 | 26286 | RNAseq | 0.6003 | 0.0058 | |
| SRP133303 | ARFGAP3 | 26286 | RNAseq | 0.6554 | 0.0046 | |
| SRP159526 | ARFGAP3 | 26286 | RNAseq | 0.5666 | 0.0024 | |
| SRP193095 | ARFGAP3 | 26286 | RNAseq | 0.1643 | 0.3202 | |
| SRP219564 | ARFGAP3 | 26286 | RNAseq | 1.1894 | 0.0106 | |
| TCGA | ARFGAP3 | 26286 | RNAseq | -0.1679 | 0.0003 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ARFGAP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ARFGAP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ARFGAP3 | 26286 | 6 | 6 | 18 | |
| GSE20123 | ARFGAP3 | 26286 | 6 | 5 | 19 | |
| GSE43470 | ARFGAP3 | 26286 | 3 | 6 | 34 | |
| GSE46452 | ARFGAP3 | 26286 | 31 | 2 | 26 | |
| GSE47630 | ARFGAP3 | 26286 | 9 | 4 | 27 | |
| GSE54993 | ARFGAP3 | 26286 | 3 | 6 | 61 | |
| GSE54994 | ARFGAP3 | 26286 | 11 | 8 | 34 | |
| GSE60625 | ARFGAP3 | 26286 | 5 | 0 | 6 | |
| GSE74703 | ARFGAP3 | 26286 | 3 | 4 | 29 | |
| GSE74704 | ARFGAP3 | 26286 | 3 | 3 | 14 | |
| TCGA | ARFGAP3 | 26286 | 26 | 14 | 56 |
Total number of gains: 106; Total number of losses: 58; Total Number of normals: 324.
Somatic mutations of ARFGAP3:
Generating mutation plots.
Highly correlated genes for ARFGAP3:
Showing top 20/867 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ARFGAP3 | ZNF766 | 0.78719 | 3 | 0 | 3 |
| ARFGAP3 | CEP120 | 0.75155 | 3 | 0 | 3 |
| ARFGAP3 | HAUS1 | 0.736741 | 3 | 0 | 3 |
| ARFGAP3 | ZBED1 | 0.733 | 4 | 0 | 4 |
| ARFGAP3 | C14orf119 | 0.731517 | 3 | 0 | 3 |
| ARFGAP3 | DUS3L | 0.724998 | 3 | 0 | 3 |
| ARFGAP3 | C12orf57 | 0.717975 | 3 | 0 | 3 |
| ARFGAP3 | TTC30B | 0.716407 | 3 | 0 | 3 |
| ARFGAP3 | TRMT6 | 0.711143 | 3 | 0 | 3 |
| ARFGAP3 | ZNF25 | 0.696656 | 3 | 0 | 3 |
| ARFGAP3 | UBTD2 | 0.691859 | 5 | 0 | 3 |
| ARFGAP3 | INPP4A | 0.687494 | 4 | 0 | 3 |
| ARFGAP3 | EFCAB7 | 0.682964 | 3 | 0 | 3 |
| ARFGAP3 | FAM89A | 0.679219 | 3 | 0 | 3 |
| ARFGAP3 | TMEM216 | 0.66711 | 3 | 0 | 3 |
| ARFGAP3 | LRRC58 | 0.666679 | 4 | 0 | 3 |
| ARFGAP3 | RFX7 | 0.666575 | 4 | 0 | 3 |
| ARFGAP3 | TCF7L2 | 0.663944 | 4 | 0 | 3 |
| ARFGAP3 | COPB1 | 0.661602 | 5 | 0 | 4 |
| ARFGAP3 | METTL9 | 0.661402 | 3 | 0 | 3 |
For details and further investigation, click here
