| Full name: BTG anti-proliferation factor 1 | Alias Symbol: APRO2 | ||
| Type: protein-coding gene | Cytoband: 12q21.33 | ||
| Entrez ID: 694 | HGNC ID: HGNC:1130 | Ensembl Gene: ENSG00000133639 | OMIM ID: 109580 |
| Drug and gene relationship at DGIdb | |||
Expression of BTG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BTG1 | 694 | 200921_s_at | 0.1789 | 0.7338 | |
| GSE20347 | BTG1 | 694 | 200921_s_at | 0.7072 | 0.0005 | |
| GSE23400 | BTG1 | 694 | 200921_s_at | 0.7800 | 0.0000 | |
| GSE26886 | BTG1 | 694 | 200921_s_at | 0.6203 | 0.0333 | |
| GSE29001 | BTG1 | 694 | 200921_s_at | 0.2986 | 0.6378 | |
| GSE38129 | BTG1 | 694 | 200921_s_at | 0.5235 | 0.0025 | |
| GSE45670 | BTG1 | 694 | 200921_s_at | 0.5019 | 0.0031 | |
| GSE53622 | BTG1 | 694 | 4827 | 0.5136 | 0.0000 | |
| GSE53624 | BTG1 | 694 | 4827 | 0.4175 | 0.0000 | |
| GSE63941 | BTG1 | 694 | 200921_s_at | -0.1185 | 0.8624 | |
| GSE77861 | BTG1 | 694 | 200921_s_at | 0.7694 | 0.0646 | |
| GSE97050 | BTG1 | 694 | A_23_P87560 | 0.4195 | 0.1887 | |
| SRP007169 | BTG1 | 694 | RNAseq | 0.6338 | 0.0352 | |
| SRP008496 | BTG1 | 694 | RNAseq | 0.5022 | 0.1008 | |
| SRP064894 | BTG1 | 694 | RNAseq | 0.4986 | 0.0147 | |
| SRP133303 | BTG1 | 694 | RNAseq | 0.2958 | 0.1927 | |
| SRP159526 | BTG1 | 694 | RNAseq | 0.3495 | 0.2343 | |
| SRP193095 | BTG1 | 694 | RNAseq | 0.2444 | 0.1410 | |
| SRP219564 | BTG1 | 694 | RNAseq | 0.4260 | 0.2214 | |
| TCGA | BTG1 | 694 | RNAseq | 0.0520 | 0.3841 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by BTG1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BTG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BTG1 | 694 | 3 | 2 | 25 | |
| GSE20123 | BTG1 | 694 | 3 | 2 | 25 | |
| GSE43470 | BTG1 | 694 | 3 | 0 | 40 | |
| GSE46452 | BTG1 | 694 | 9 | 1 | 49 | |
| GSE47630 | BTG1 | 694 | 10 | 1 | 29 | |
| GSE54993 | BTG1 | 694 | 0 | 6 | 64 | |
| GSE54994 | BTG1 | 694 | 6 | 1 | 46 | |
| GSE60625 | BTG1 | 694 | 0 | 0 | 11 | |
| GSE74703 | BTG1 | 694 | 3 | 0 | 33 | |
| GSE74704 | BTG1 | 694 | 1 | 2 | 17 | |
| TCGA | BTG1 | 694 | 17 | 11 | 68 |
Total number of gains: 55; Total number of losses: 26; Total Number of normals: 407.
Somatic mutations of BTG1:
Generating mutation plots.
Highly correlated genes for BTG1:
Showing top 20/794 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BTG1 | FAM168B | 0.780556 | 3 | 0 | 3 |
| BTG1 | FNDC3A | 0.75467 | 3 | 0 | 3 |
| BTG1 | PREX1 | 0.749408 | 3 | 0 | 3 |
| BTG1 | TTLL1 | 0.740547 | 3 | 0 | 3 |
| BTG1 | ZSCAN21 | 0.737939 | 4 | 0 | 4 |
| BTG1 | TGFBRAP1 | 0.732284 | 3 | 0 | 3 |
| BTG1 | ZBED1 | 0.731873 | 4 | 0 | 4 |
| BTG1 | DUS3L | 0.726819 | 4 | 0 | 4 |
| BTG1 | NOA1 | 0.723799 | 3 | 0 | 3 |
| BTG1 | IPO5 | 0.723436 | 3 | 0 | 3 |
| BTG1 | RPS19BP1 | 0.721797 | 3 | 0 | 3 |
| BTG1 | CCDC97 | 0.721532 | 3 | 0 | 3 |
| BTG1 | SMARCE1 | 0.720339 | 4 | 0 | 3 |
| BTG1 | CHST3 | 0.707928 | 3 | 0 | 3 |
| BTG1 | EVL | 0.70554 | 4 | 0 | 3 |
| BTG1 | NUDT3 | 0.704889 | 3 | 0 | 3 |
| BTG1 | PLSCR1 | 0.703622 | 3 | 0 | 3 |
| BTG1 | TNFRSF1B | 0.698828 | 4 | 0 | 4 |
| BTG1 | ZNF704 | 0.698562 | 3 | 0 | 3 |
| BTG1 | TRIM8 | 0.696431 | 3 | 0 | 3 |
For details and further investigation, click here
