| Full name: ribosomal protein L34 | Alias Symbol: L34 | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 6164 | HGNC ID: HGNC:10340 | Ensembl Gene: ENSG00000109475 | OMIM ID: 616862 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL34:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL34 | 6164 | 200026_at | -0.1921 | 0.4121 | |
| GSE20347 | RPL34 | 6164 | 200026_at | -0.1873 | 0.0221 | |
| GSE23400 | RPL34 | 6164 | 200026_at | -0.2269 | 0.0000 | |
| GSE26886 | RPL34 | 6164 | 200026_at | 0.4224 | 0.0042 | |
| GSE29001 | RPL34 | 6164 | 200026_at | -0.2535 | 0.1211 | |
| GSE38129 | RPL34 | 6164 | 200026_at | -0.2889 | 0.0009 | |
| GSE45670 | RPL34 | 6164 | 200026_at | -0.4456 | 0.0000 | |
| GSE53622 | RPL34 | 6164 | 46535 | -0.6828 | 0.0000 | |
| GSE53624 | RPL34 | 6164 | 46535 | -0.1901 | 0.0010 | |
| GSE63941 | RPL34 | 6164 | 200026_at | 0.1821 | 0.2878 | |
| GSE77861 | RPL34 | 6164 | 200026_at | -0.2945 | 0.0716 | |
| GSE97050 | RPL34 | 6164 | A_23_P7221 | -0.4733 | 0.1756 | |
| SRP007169 | RPL34 | 6164 | RNAseq | -1.0605 | 0.0009 | |
| SRP008496 | RPL34 | 6164 | RNAseq | -1.0841 | 0.0000 | |
| SRP064894 | RPL34 | 6164 | RNAseq | -0.4858 | 0.2232 | |
| SRP133303 | RPL34 | 6164 | RNAseq | -0.6128 | 0.0001 | |
| SRP159526 | RPL34 | 6164 | RNAseq | -1.1066 | 0.0000 | |
| SRP193095 | RPL34 | 6164 | RNAseq | -1.3862 | 0.0000 | |
| SRP219564 | RPL34 | 6164 | RNAseq | -0.5682 | 0.0857 | |
| TCGA | RPL34 | 6164 | RNAseq | -0.0603 | 0.3341 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by RPL34 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL34:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL34 | 6164 | 0 | 12 | 18 | |
| GSE20123 | RPL34 | 6164 | 0 | 12 | 18 | |
| GSE43470 | RPL34 | 6164 | 0 | 13 | 30 | |
| GSE46452 | RPL34 | 6164 | 1 | 36 | 22 | |
| GSE47630 | RPL34 | 6164 | 0 | 20 | 20 | |
| GSE54993 | RPL34 | 6164 | 9 | 0 | 61 | |
| GSE54994 | RPL34 | 6164 | 1 | 10 | 42 | |
| GSE60625 | RPL34 | 6164 | 0 | 3 | 8 | |
| GSE74703 | RPL34 | 6164 | 0 | 11 | 25 | |
| GSE74704 | RPL34 | 6164 | 0 | 6 | 14 | |
| TCGA | RPL34 | 6164 | 8 | 35 | 53 |
Total number of gains: 19; Total number of losses: 158; Total Number of normals: 311.
Somatic mutations of RPL34:
Generating mutation plots.
Highly correlated genes for RPL34:
Showing top 20/484 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL34 | NUDT17 | 0.727874 | 3 | 0 | 3 |
| RPL34 | VAMP1 | 0.722161 | 3 | 0 | 3 |
| RPL34 | KPNA5 | 0.717971 | 3 | 0 | 3 |
| RPL34 | LINC01315 | 0.708991 | 4 | 0 | 4 |
| RPL34 | PTRHD1 | 0.705117 | 4 | 0 | 4 |
| RPL34 | TMEM38A | 0.703195 | 3 | 0 | 3 |
| RPL34 | UTRN | 0.700556 | 4 | 0 | 4 |
| RPL34 | CRLS1 | 0.694936 | 3 | 0 | 3 |
| RPL34 | EVC2 | 0.692692 | 3 | 0 | 3 |
| RPL34 | RPL10A | 0.692337 | 9 | 0 | 7 |
| RPL34 | ZNF839 | 0.68562 | 3 | 0 | 3 |
| RPL34 | ZMAT1 | 0.68383 | 5 | 0 | 4 |
| RPL34 | ZNF573 | 0.683602 | 3 | 0 | 3 |
| RPL34 | TXNIP | 0.681006 | 4 | 0 | 4 |
| RPL34 | NDUFC1 | 0.676775 | 8 | 0 | 8 |
| RPL34 | SLC46A3 | 0.673794 | 3 | 0 | 3 |
| RPL34 | SLC25A27 | 0.671566 | 3 | 0 | 3 |
| RPL34 | RPL32 | 0.667593 | 12 | 0 | 9 |
| RPL34 | RPS9 | 0.666065 | 10 | 0 | 9 |
| RPL34 | RPS25 | 0.665649 | 11 | 0 | 11 |
For details and further investigation, click here
