| Full name: solute carrier family 46 member 3 | Alias Symbol: DKFZp686A1775|FLJ42613 | ||
| Type: protein-coding gene | Cytoband: 13q12.3 | ||
| Entrez ID: 283537 | HGNC ID: HGNC:27501 | Ensembl Gene: ENSG00000139508 | OMIM ID: 616764 |
Expression of SLC46A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC46A3 | 283537 | 214719_at | -0.4809 | 0.5452 | |
| GSE20347 | SLC46A3 | 283537 | 214719_at | -0.4274 | 0.0124 | |
| GSE23400 | SLC46A3 | 283537 | 214719_at | -0.0279 | 0.7587 | |
| GSE26886 | SLC46A3 | 283537 | 214719_at | 0.1144 | 0.8656 | |
| GSE29001 | SLC46A3 | 283537 | 214719_at | -0.5136 | 0.1461 | |
| GSE38129 | SLC46A3 | 283537 | 214719_at | -0.6910 | 0.0128 | |
| GSE45670 | SLC46A3 | 283537 | 214719_at | -1.1564 | 0.0001 | |
| GSE53622 | SLC46A3 | 283537 | 98210 | -0.2455 | 0.0409 | |
| GSE53624 | SLC46A3 | 283537 | 98210 | -0.2901 | 0.0889 | |
| GSE63941 | SLC46A3 | 283537 | 214719_at | -1.6882 | 0.0662 | |
| GSE77861 | SLC46A3 | 283537 | 214719_at | -0.1503 | 0.4861 | |
| GSE97050 | SLC46A3 | 283537 | A_23_P205074 | -0.0865 | 0.6812 | |
| SRP007169 | SLC46A3 | 283537 | RNAseq | 0.9382 | 0.1896 | |
| SRP008496 | SLC46A3 | 283537 | RNAseq | 0.5623 | 0.2037 | |
| SRP064894 | SLC46A3 | 283537 | RNAseq | 0.1697 | 0.5065 | |
| SRP133303 | SLC46A3 | 283537 | RNAseq | -0.0643 | 0.8349 | |
| SRP159526 | SLC46A3 | 283537 | RNAseq | 0.1493 | 0.7796 | |
| SRP193095 | SLC46A3 | 283537 | RNAseq | -0.8801 | 0.0070 | |
| SRP219564 | SLC46A3 | 283537 | RNAseq | -0.1643 | 0.7498 | |
| TCGA | SLC46A3 | 283537 | RNAseq | -0.4342 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC46A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC46A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC46A3 | 283537 | 1 | 13 | 16 | |
| GSE20123 | SLC46A3 | 283537 | 1 | 12 | 17 | |
| GSE43470 | SLC46A3 | 283537 | 2 | 12 | 29 | |
| GSE46452 | SLC46A3 | 283537 | 0 | 33 | 26 | |
| GSE47630 | SLC46A3 | 283537 | 3 | 26 | 11 | |
| GSE54993 | SLC46A3 | 283537 | 12 | 2 | 56 | |
| GSE54994 | SLC46A3 | 283537 | 2 | 13 | 38 | |
| GSE60625 | SLC46A3 | 283537 | 0 | 3 | 8 | |
| GSE74703 | SLC46A3 | 283537 | 2 | 9 | 25 | |
| GSE74704 | SLC46A3 | 283537 | 0 | 10 | 10 | |
| TCGA | SLC46A3 | 283537 | 8 | 38 | 50 |
Total number of gains: 31; Total number of losses: 171; Total Number of normals: 286.
Somatic mutations of SLC46A3:
Generating mutation plots.
Highly correlated genes for SLC46A3:
Showing top 20/993 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC46A3 | AFF3 | 0.745021 | 3 | 0 | 3 |
| SLC46A3 | NMT2 | 0.724854 | 4 | 0 | 4 |
| SLC46A3 | TAGAP | 0.699879 | 4 | 0 | 3 |
| SLC46A3 | HIPK3 | 0.699844 | 3 | 0 | 3 |
| SLC46A3 | TNFSF8 | 0.696212 | 4 | 0 | 4 |
| SLC46A3 | CNRIP1 | 0.694227 | 6 | 0 | 5 |
| SLC46A3 | OLFML1 | 0.694145 | 8 | 0 | 8 |
| SLC46A3 | GIMAP5 | 0.691564 | 4 | 0 | 4 |
| SLC46A3 | AXL | 0.690903 | 8 | 0 | 6 |
| SLC46A3 | NFATC4 | 0.688497 | 4 | 0 | 4 |
| SLC46A3 | FAM13C | 0.688025 | 4 | 0 | 4 |
| SLC46A3 | RPS9 | 0.687967 | 4 | 0 | 3 |
| SLC46A3 | GIMAP1 | 0.687913 | 6 | 0 | 5 |
| SLC46A3 | CLEC14A | 0.68491 | 5 | 0 | 4 |
| SLC46A3 | ARHGEF6 | 0.683929 | 12 | 0 | 11 |
| SLC46A3 | MAPRE2 | 0.683087 | 6 | 0 | 6 |
| SLC46A3 | POLK | 0.682198 | 4 | 0 | 3 |
| SLC46A3 | TNFSF12 | 0.681409 | 4 | 0 | 3 |
| SLC46A3 | C3 | 0.681338 | 7 | 0 | 7 |
| SLC46A3 | MACROD2 | 0.679733 | 4 | 0 | 3 |
For details and further investigation, click here
