| Full name: utrophin | Alias Symbol: DRP|DRP1 | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 7402 | HGNC ID: HGNC:12635 | Ensembl Gene: ENSG00000152818 | OMIM ID: 128240 |
| Drug and gene relationship at DGIdb | |||
Expression of UTRN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | UTRN | 7402 | 225093_at | -1.1019 | 0.0127 | |
| GSE20347 | UTRN | 7402 | 213023_at | -0.0991 | 0.2240 | |
| GSE23400 | UTRN | 7402 | 213022_s_at | -0.1581 | 0.0098 | |
| GSE26886 | UTRN | 7402 | 225093_at | -0.3752 | 0.3428 | |
| GSE29001 | UTRN | 7402 | 213022_s_at | -0.3608 | 0.0040 | |
| GSE38129 | UTRN | 7402 | 213022_s_at | -0.2255 | 0.0152 | |
| GSE45670 | UTRN | 7402 | 225093_at | -1.2449 | 0.0000 | |
| GSE53622 | UTRN | 7402 | 3040 | -1.0744 | 0.0000 | |
| GSE53624 | UTRN | 7402 | 99438 | -1.1772 | 0.0000 | |
| GSE63941 | UTRN | 7402 | 225093_at | -1.3026 | 0.1527 | |
| GSE77861 | UTRN | 7402 | 225093_at | -0.4175 | 0.3215 | |
| GSE97050 | UTRN | 7402 | A_33_P3234855 | -0.6311 | 0.0635 | |
| SRP007169 | UTRN | 7402 | RNAseq | 0.8709 | 0.0684 | |
| SRP008496 | UTRN | 7402 | RNAseq | 1.2393 | 0.0002 | |
| SRP064894 | UTRN | 7402 | RNAseq | -0.5743 | 0.0928 | |
| SRP133303 | UTRN | 7402 | RNAseq | -0.9942 | 0.0000 | |
| SRP159526 | UTRN | 7402 | RNAseq | -0.8233 | 0.0087 | |
| SRP193095 | UTRN | 7402 | RNAseq | -0.6657 | 0.0001 | |
| SRP219564 | UTRN | 7402 | RNAseq | -0.6066 | 0.3148 | |
| TCGA | UTRN | 7402 | RNAseq | -0.3704 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 4.
Survival by UTRN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of UTRN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | UTRN | 7402 | 2 | 4 | 24 | |
| GSE20123 | UTRN | 7402 | 2 | 3 | 25 | |
| GSE43470 | UTRN | 7402 | 5 | 0 | 38 | |
| GSE46452 | UTRN | 7402 | 3 | 10 | 46 | |
| GSE47630 | UTRN | 7402 | 9 | 4 | 27 | |
| GSE54993 | UTRN | 7402 | 3 | 2 | 65 | |
| GSE54994 | UTRN | 7402 | 8 | 8 | 37 | |
| GSE60625 | UTRN | 7402 | 0 | 1 | 10 | |
| GSE74703 | UTRN | 7402 | 4 | 0 | 32 | |
| GSE74704 | UTRN | 7402 | 0 | 1 | 19 | |
| TCGA | UTRN | 7402 | 12 | 23 | 61 |
Total number of gains: 48; Total number of losses: 56; Total Number of normals: 384.
Somatic mutations of UTRN:
Generating mutation plots.
Highly correlated genes for UTRN:
Showing top 20/1400 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| UTRN | ANGPTL1 | 0.822731 | 5 | 0 | 5 |
| UTRN | CLEC3B | 0.8081 | 3 | 0 | 3 |
| UTRN | RAB9B | 0.795419 | 5 | 0 | 5 |
| UTRN | C1QTNF7 | 0.780179 | 5 | 0 | 5 |
| UTRN | IGSF10 | 0.780142 | 5 | 0 | 5 |
| UTRN | CYP21A2 | 0.779986 | 3 | 0 | 3 |
| UTRN | SLITRK3 | 0.776306 | 5 | 0 | 5 |
| UTRN | RGS7BP | 0.770807 | 5 | 0 | 5 |
| UTRN | CGNL1 | 0.769119 | 6 | 0 | 6 |
| UTRN | SH3D19 | 0.766413 | 4 | 0 | 4 |
| UTRN | SORBS1 | 0.759046 | 5 | 0 | 5 |
| UTRN | ABI3BP | 0.757451 | 6 | 0 | 6 |
| UTRN | OGN | 0.756478 | 6 | 0 | 5 |
| UTRN | NR2F1 | 0.754088 | 3 | 0 | 3 |
| UTRN | RECK | 0.753634 | 4 | 0 | 4 |
| UTRN | NOSTRIN | 0.752282 | 4 | 0 | 4 |
| UTRN | LRRC20 | 0.744922 | 3 | 0 | 3 |
| UTRN | PPP3CC | 0.743549 | 3 | 0 | 3 |
| UTRN | APOD | 0.739306 | 6 | 0 | 5 |
| UTRN | MAMDC2 | 0.738091 | 6 | 0 | 5 |
For details and further investigation, click here
