| Full name: solute carrier family 25 member 27 | Alias Symbol: UCP4|FLJ33552 | ||
| Type: protein-coding gene | Cytoband: 6p12.3 | ||
| Entrez ID: 9481 | HGNC ID: HGNC:21065 | Ensembl Gene: ENSG00000153291 | OMIM ID: 613725 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC25A27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A27 | 9481 | 230624_at | -0.6613 | 0.1730 | |
| GSE26886 | SLC25A27 | 9481 | 229361_at | -0.0883 | 0.4463 | |
| GSE45670 | SLC25A27 | 9481 | 229361_at | 0.0111 | 0.9287 | |
| GSE53622 | SLC25A27 | 9481 | 143425 | -0.2875 | 0.1049 | |
| GSE53624 | SLC25A27 | 9481 | 143425 | -0.3068 | 0.0139 | |
| GSE63941 | SLC25A27 | 9481 | 230624_at | -2.1137 | 0.0073 | |
| GSE77861 | SLC25A27 | 9481 | 229361_at | -0.1604 | 0.0944 | |
| GSE97050 | SLC25A27 | 9481 | A_24_P246841 | -0.5945 | 0.1339 | |
| SRP064894 | SLC25A27 | 9481 | RNAseq | -0.3915 | 0.0620 | |
| SRP133303 | SLC25A27 | 9481 | RNAseq | -0.6174 | 0.1192 | |
| SRP159526 | SLC25A27 | 9481 | RNAseq | -0.2962 | 0.5782 | |
| SRP193095 | SLC25A27 | 9481 | RNAseq | 0.0975 | 0.5520 | |
| SRP219564 | SLC25A27 | 9481 | RNAseq | -0.3099 | 0.5160 | |
| TCGA | SLC25A27 | 9481 | RNAseq | -0.6050 | 0.0030 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SLC25A27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A27 | 9481 | 6 | 2 | 22 | |
| GSE20123 | SLC25A27 | 9481 | 6 | 2 | 22 | |
| GSE43470 | SLC25A27 | 9481 | 5 | 0 | 38 | |
| GSE46452 | SLC25A27 | 9481 | 2 | 10 | 47 | |
| GSE47630 | SLC25A27 | 9481 | 7 | 5 | 28 | |
| GSE54993 | SLC25A27 | 9481 | 3 | 1 | 66 | |
| GSE54994 | SLC25A27 | 9481 | 8 | 3 | 42 | |
| GSE60625 | SLC25A27 | 9481 | 0 | 3 | 8 | |
| GSE74703 | SLC25A27 | 9481 | 5 | 0 | 31 | |
| GSE74704 | SLC25A27 | 9481 | 2 | 1 | 17 | |
| TCGA | SLC25A27 | 9481 | 18 | 14 | 64 |
Total number of gains: 62; Total number of losses: 41; Total Number of normals: 385.
Somatic mutations of SLC25A27:
Generating mutation plots.
Highly correlated genes for SLC25A27:
Showing top 20/242 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A27 | FBXW7 | 0.802976 | 3 | 0 | 3 |
| SLC25A27 | GNAQ | 0.801581 | 3 | 0 | 3 |
| SLC25A27 | ABCA3 | 0.764294 | 3 | 0 | 3 |
| SLC25A27 | C1QTNF7 | 0.757248 | 3 | 0 | 3 |
| SLC25A27 | EGLN1 | 0.753602 | 3 | 0 | 3 |
| SLC25A27 | USP9Y | 0.753554 | 3 | 0 | 3 |
| SLC25A27 | GRHPR | 0.749362 | 3 | 0 | 3 |
| SLC25A27 | CYTH2 | 0.747953 | 3 | 0 | 3 |
| SLC25A27 | PHYHD1 | 0.746616 | 3 | 0 | 3 |
| SLC25A27 | KIAA1191 | 0.745198 | 3 | 0 | 3 |
| SLC25A27 | SST | 0.739045 | 3 | 0 | 3 |
| SLC25A27 | HCFC2 | 0.737408 | 3 | 0 | 3 |
| SLC25A27 | PEG3 | 0.734817 | 3 | 0 | 3 |
| SLC25A27 | LRRFIP2 | 0.73414 | 3 | 0 | 3 |
| SLC25A27 | GNG7 | 0.728061 | 3 | 0 | 3 |
| SLC25A27 | LIMD2 | 0.726815 | 3 | 0 | 3 |
| SLC25A27 | PTPN21 | 0.72651 | 3 | 0 | 3 |
| SLC25A27 | FYCO1 | 0.722684 | 4 | 0 | 4 |
| SLC25A27 | SLC16A4 | 0.72228 | 3 | 0 | 3 |
| SLC25A27 | PER3 | 0.721854 | 3 | 0 | 3 |
For details and further investigation, click here
