| Full name: hypocretin receptor 1 | Alias Symbol: OX1R | ||
| Type: protein-coding gene | Cytoband: 1p35.2 | ||
| Entrez ID: 3061 | HGNC ID: HGNC:4848 | Ensembl Gene: ENSG00000121764 | OMIM ID: 602392 |
| Drug and gene relationship at DGIdb | |||
Expression of HCRTR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HCRTR1 | 3061 | 207619_at | 0.0839 | 0.7200 | |
| GSE20347 | HCRTR1 | 3061 | 207619_at | -0.0713 | 0.1906 | |
| GSE23400 | HCRTR1 | 3061 | 207619_at | -0.0317 | 0.1204 | |
| GSE26886 | HCRTR1 | 3061 | 207619_at | 0.1089 | 0.3068 | |
| GSE29001 | HCRTR1 | 3061 | 207619_at | -0.1178 | 0.3405 | |
| GSE38129 | HCRTR1 | 3061 | 207619_at | -0.0779 | 0.1067 | |
| GSE45670 | HCRTR1 | 3061 | 207619_at | 0.0396 | 0.6766 | |
| GSE53622 | HCRTR1 | 3061 | 38819 | 0.1041 | 0.1531 | |
| GSE53624 | HCRTR1 | 3061 | 38819 | 0.0175 | 0.8628 | |
| GSE63941 | HCRTR1 | 3061 | 207619_at | 0.1912 | 0.1562 | |
| GSE77861 | HCRTR1 | 3061 | 207619_at | 0.0627 | 0.5570 | |
| GSE97050 | HCRTR1 | 3061 | A_33_P3360249 | -0.0252 | 0.9078 | |
| SRP133303 | HCRTR1 | 3061 | RNAseq | -1.6002 | 0.0002 | |
| TCGA | HCRTR1 | 3061 | RNAseq | -2.9545 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by HCRTR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HCRTR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HCRTR1 | 3061 | 1 | 5 | 24 | |
| GSE20123 | HCRTR1 | 3061 | 1 | 4 | 25 | |
| GSE43470 | HCRTR1 | 3061 | 6 | 4 | 33 | |
| GSE46452 | HCRTR1 | 3061 | 5 | 1 | 53 | |
| GSE47630 | HCRTR1 | 3061 | 8 | 3 | 29 | |
| GSE54993 | HCRTR1 | 3061 | 1 | 1 | 68 | |
| GSE54994 | HCRTR1 | 3061 | 11 | 2 | 40 | |
| GSE60625 | HCRTR1 | 3061 | 0 | 0 | 11 | |
| GSE74703 | HCRTR1 | 3061 | 4 | 3 | 29 | |
| GSE74704 | HCRTR1 | 3061 | 0 | 0 | 20 | |
| TCGA | HCRTR1 | 3061 | 12 | 19 | 65 |
Total number of gains: 49; Total number of losses: 42; Total Number of normals: 397.
Somatic mutations of HCRTR1:
Generating mutation plots.
Highly correlated genes for HCRTR1:
Showing top 20/707 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HCRTR1 | BSX | 0.78389 | 3 | 0 | 3 |
| HCRTR1 | C1QL2 | 0.783035 | 3 | 0 | 3 |
| HCRTR1 | PABPN1L | 0.774231 | 3 | 0 | 3 |
| HCRTR1 | INSC | 0.76219 | 3 | 0 | 3 |
| HCRTR1 | YY2 | 0.761148 | 3 | 0 | 3 |
| HCRTR1 | SPACA3 | 0.754645 | 3 | 0 | 3 |
| HCRTR1 | STRC | 0.754508 | 3 | 0 | 3 |
| HCRTR1 | PRSS38 | 0.742748 | 3 | 0 | 3 |
| HCRTR1 | VAV2 | 0.740298 | 3 | 0 | 3 |
| HCRTR1 | ABTB1 | 0.73731 | 3 | 0 | 3 |
| HCRTR1 | WDR87 | 0.737038 | 3 | 0 | 3 |
| HCRTR1 | OR2T27 | 0.736885 | 3 | 0 | 3 |
| HCRTR1 | LCT | 0.735719 | 3 | 0 | 3 |
| HCRTR1 | CLCNKA | 0.732716 | 3 | 0 | 3 |
| HCRTR1 | BBC3 | 0.72802 | 3 | 0 | 3 |
| HCRTR1 | SYPL2 | 0.72767 | 3 | 0 | 3 |
| HCRTR1 | SHC2 | 0.727399 | 3 | 0 | 3 |
| HCRTR1 | SAMD4A | 0.725888 | 3 | 0 | 3 |
| HCRTR1 | C10orf91 | 0.724117 | 3 | 0 | 3 |
| HCRTR1 | C19orf44 | 0.72365 | 3 | 0 | 3 |
For details and further investigation, click here
