| Full name: developing brain homeobox 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 120237 | HGNC ID: HGNC:33185 | Ensembl Gene: ENSG00000109851 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DBX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | DBX1 | 120237 | 3586 | -0.0950 | 0.0640 | |
| GSE53624 | DBX1 | 120237 | 3586 | 0.0913 | 0.2064 | |
| GSE97050 | DBX1 | 120237 | A_33_P3407350 | 0.0067 | 0.9808 | |
| TCGA | DBX1 | 120237 | RNAseq | 1.1253 | 0.6598 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DBX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DBX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DBX1 | 120237 | 0 | 9 | 21 | |
| GSE20123 | DBX1 | 120237 | 0 | 10 | 20 | |
| GSE43470 | DBX1 | 120237 | 1 | 5 | 37 | |
| GSE46452 | DBX1 | 120237 | 7 | 5 | 47 | |
| GSE47630 | DBX1 | 120237 | 3 | 10 | 27 | |
| GSE54993 | DBX1 | 120237 | 3 | 0 | 67 | |
| GSE54994 | DBX1 | 120237 | 3 | 12 | 38 | |
| GSE60625 | DBX1 | 120237 | 0 | 0 | 11 | |
| GSE74703 | DBX1 | 120237 | 1 | 3 | 32 | |
| GSE74704 | DBX1 | 120237 | 0 | 8 | 12 | |
| TCGA | DBX1 | 120237 | 13 | 26 | 57 |
Total number of gains: 31; Total number of losses: 88; Total Number of normals: 369.
Somatic mutations of DBX1:
Generating mutation plots.
Highly correlated genes for DBX1:
Showing top 20/43 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DBX1 | CHMP6 | 0.777209 | 3 | 0 | 3 |
| DBX1 | FZD9 | 0.765591 | 3 | 0 | 3 |
| DBX1 | SAMD4A | 0.764585 | 3 | 0 | 3 |
| DBX1 | ANKRD33B | 0.751337 | 3 | 0 | 3 |
| DBX1 | TSPAN11 | 0.750198 | 3 | 0 | 3 |
| DBX1 | SLC22A7 | 0.74977 | 3 | 0 | 3 |
| DBX1 | CPLX2 | 0.747969 | 3 | 0 | 3 |
| DBX1 | LHX9 | 0.74547 | 3 | 0 | 3 |
| DBX1 | SPACA3 | 0.744946 | 3 | 0 | 3 |
| DBX1 | GRIK4 | 0.741818 | 3 | 0 | 3 |
| DBX1 | UFSP1 | 0.737749 | 3 | 0 | 3 |
| DBX1 | TOR2A | 0.736594 | 3 | 0 | 3 |
| DBX1 | ZNF329 | 0.729609 | 3 | 0 | 3 |
| DBX1 | STAC3 | 0.728665 | 3 | 0 | 3 |
| DBX1 | KIRREL2 | 0.727595 | 3 | 0 | 3 |
| DBX1 | FBRSL1 | 0.717335 | 3 | 0 | 3 |
| DBX1 | NKX6-3 | 0.71661 | 3 | 0 | 3 |
| DBX1 | C8G | 0.71568 | 3 | 0 | 3 |
| DBX1 | EVX1 | 0.713026 | 3 | 0 | 3 |
| DBX1 | TNNI2 | 0.712981 | 3 | 0 | 3 |
For details and further investigation, click here
