| Full name: lacritin | Alias Symbol: LACRITIN | ||
| Type: protein-coding gene | Cytoband: 12q13.2 | ||
| Entrez ID: 90070 | HGNC ID: HGNC:16430 | Ensembl Gene: ENSG00000135413 | OMIM ID: 607360 |
| Drug and gene relationship at DGIdb | |||
Expression of LACRT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LACRT | 90070 | 224540_at | -0.1825 | 0.3398 | |
| GSE26886 | LACRT | 90070 | 224540_at | -0.0428 | 0.7667 | |
| GSE45670 | LACRT | 90070 | 224540_at | -0.0764 | 0.2655 | |
| GSE53622 | LACRT | 90070 | 112684 | 0.3401 | 0.0003 | |
| GSE53624 | LACRT | 90070 | 112684 | 0.2498 | 0.0248 | |
| GSE63941 | LACRT | 90070 | 224540_at | 0.2427 | 0.0628 | |
| GSE77861 | LACRT | 90070 | 224540_at | -0.1408 | 0.1892 | |
| GSE97050 | LACRT | 90070 | A_23_P64825 | 0.1740 | 0.4051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LACRT expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LACRT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LACRT | 90070 | 4 | 1 | 25 | |
| GSE20123 | LACRT | 90070 | 4 | 1 | 25 | |
| GSE43470 | LACRT | 90070 | 5 | 0 | 38 | |
| GSE46452 | LACRT | 90070 | 7 | 1 | 51 | |
| GSE47630 | LACRT | 90070 | 10 | 2 | 28 | |
| GSE54993 | LACRT | 90070 | 0 | 5 | 65 | |
| GSE54994 | LACRT | 90070 | 4 | 1 | 48 | |
| GSE60625 | LACRT | 90070 | 0 | 0 | 11 | |
| GSE74703 | LACRT | 90070 | 4 | 0 | 32 | |
| GSE74704 | LACRT | 90070 | 3 | 1 | 16 | |
| TCGA | LACRT | 90070 | 16 | 11 | 69 |
Total number of gains: 57; Total number of losses: 23; Total Number of normals: 408.
Somatic mutations of LACRT:
Generating mutation plots.
Highly correlated genes for LACRT:
Showing top 20/428 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LACRT | SLC6A3 | 0.75988 | 3 | 0 | 3 |
| LACRT | CTSE | 0.756934 | 3 | 0 | 3 |
| LACRT | SLC6A13 | 0.752724 | 3 | 0 | 3 |
| LACRT | STRC | 0.750336 | 3 | 0 | 3 |
| LACRT | PKD2L1 | 0.743601 | 4 | 0 | 4 |
| LACRT | NOG | 0.738856 | 3 | 0 | 3 |
| LACRT | KCNMB2 | 0.737381 | 3 | 0 | 3 |
| LACRT | SAMD4A | 0.736854 | 3 | 0 | 3 |
| LACRT | ASTL | 0.73353 | 3 | 0 | 3 |
| LACRT | RP1L1 | 0.7334 | 3 | 0 | 3 |
| LACRT | CYP17A1 | 0.7325 | 4 | 0 | 4 |
| LACRT | MYO1A | 0.731652 | 4 | 0 | 4 |
| LACRT | LRTM1 | 0.730591 | 3 | 0 | 3 |
| LACRT | PLA2G2C | 0.728782 | 3 | 0 | 3 |
| LACRT | PTAFR | 0.724871 | 3 | 0 | 3 |
| LACRT | MUC8 | 0.721057 | 4 | 0 | 4 |
| LACRT | OR2T27 | 0.72025 | 3 | 0 | 3 |
| LACRT | OR2A5 | 0.7192 | 3 | 0 | 3 |
| LACRT | DCDC1 | 0.715353 | 3 | 0 | 3 |
| LACRT | OR10H1 | 0.714638 | 3 | 0 | 3 |
For details and further investigation, click here
