| Full name: saccharopine dehydrogenase (putative) | Alias Symbol: CGI-49|NET11 | ||
| Type: protein-coding gene | Cytoband: 1q44 | ||
| Entrez ID: 51097 | HGNC ID: HGNC:24275 | Ensembl Gene: ENSG00000143653 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SCCPDH:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SCCPDH | 51097 | 201825_s_at | 0.5491 | 0.5809 | |
| GSE20347 | SCCPDH | 51097 | 201825_s_at | 1.1523 | 0.0000 | |
| GSE23400 | SCCPDH | 51097 | 201825_s_at | 0.4848 | 0.0000 | |
| GSE26886 | SCCPDH | 51097 | 201825_s_at | 1.8174 | 0.0000 | |
| GSE29001 | SCCPDH | 51097 | 201825_s_at | 0.8499 | 0.0075 | |
| GSE38129 | SCCPDH | 51097 | 201825_s_at | 0.7877 | 0.0082 | |
| GSE45670 | SCCPDH | 51097 | 201825_s_at | 0.0237 | 0.9634 | |
| GSE53622 | SCCPDH | 51097 | 5430 | 0.8905 | 0.0000 | |
| GSE53624 | SCCPDH | 51097 | 5430 | 0.9992 | 0.0000 | |
| GSE63941 | SCCPDH | 51097 | 201825_s_at | -1.6701 | 0.2271 | |
| GSE77861 | SCCPDH | 51097 | 201825_s_at | 0.8901 | 0.0185 | |
| GSE97050 | SCCPDH | 51097 | A_23_P62807 | 0.1451 | 0.6965 | |
| SRP007169 | SCCPDH | 51097 | RNAseq | 3.9618 | 0.0000 | |
| SRP008496 | SCCPDH | 51097 | RNAseq | 4.6448 | 0.0000 | |
| SRP064894 | SCCPDH | 51097 | RNAseq | 0.9491 | 0.0002 | |
| SRP133303 | SCCPDH | 51097 | RNAseq | 1.0417 | 0.0000 | |
| SRP159526 | SCCPDH | 51097 | RNAseq | 1.2789 | 0.0006 | |
| SRP193095 | SCCPDH | 51097 | RNAseq | 0.4878 | 0.1928 | |
| SRP219564 | SCCPDH | 51097 | RNAseq | 0.8683 | 0.1681 | |
| TCGA | SCCPDH | 51097 | RNAseq | -0.2726 | 0.0185 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SCCPDH expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SCCPDH:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SCCPDH | 51097 | 7 | 1 | 22 | |
| GSE20123 | SCCPDH | 51097 | 7 | 1 | 22 | |
| GSE43470 | SCCPDH | 51097 | 4 | 3 | 36 | |
| GSE46452 | SCCPDH | 51097 | 4 | 2 | 53 | |
| GSE47630 | SCCPDH | 51097 | 15 | 1 | 24 | |
| GSE54993 | SCCPDH | 51097 | 0 | 6 | 64 | |
| GSE54994 | SCCPDH | 51097 | 18 | 0 | 35 | |
| GSE60625 | SCCPDH | 51097 | 0 | 0 | 11 | |
| GSE74703 | SCCPDH | 51097 | 4 | 1 | 31 | |
| GSE74704 | SCCPDH | 51097 | 2 | 0 | 18 | |
| TCGA | SCCPDH | 51097 | 46 | 5 | 45 |
Total number of gains: 107; Total number of losses: 20; Total Number of normals: 361.
Somatic mutations of SCCPDH:
Generating mutation plots.
Highly correlated genes for SCCPDH:
Showing top 20/1542 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SCCPDH | PET117 | 0.775797 | 3 | 0 | 3 |
| SCCPDH | SSBP4 | 0.765481 | 4 | 0 | 4 |
| SCCPDH | MTERF1 | 0.755056 | 3 | 0 | 3 |
| SCCPDH | FADS1 | 0.754288 | 3 | 0 | 3 |
| SCCPDH | ZNF704 | 0.7533 | 3 | 0 | 3 |
| SCCPDH | CENPV | 0.74154 | 7 | 0 | 7 |
| SCCPDH | ALKBH6 | 0.74144 | 3 | 0 | 3 |
| SCCPDH | GRAMD1A | 0.740301 | 6 | 0 | 6 |
| SCCPDH | RAB34 | 0.735558 | 3 | 0 | 3 |
| SCCPDH | ZNF275 | 0.729301 | 7 | 0 | 7 |
| SCCPDH | DYNC2H1 | 0.718072 | 3 | 0 | 3 |
| SCCPDH | SHANK3 | 0.716001 | 3 | 0 | 3 |
| SCCPDH | SLC41A1 | 0.713735 | 6 | 0 | 5 |
| SCCPDH | TRMT6 | 0.712159 | 3 | 0 | 3 |
| SCCPDH | NF1 | 0.711241 | 3 | 0 | 3 |
| SCCPDH | ZNF121 | 0.710088 | 3 | 0 | 3 |
| SCCPDH | GRB10 | 0.708274 | 10 | 0 | 10 |
| SCCPDH | PPRC1 | 0.706118 | 4 | 0 | 3 |
| SCCPDH | THOC1 | 0.701607 | 4 | 0 | 4 |
| SCCPDH | DHRSX | 0.699979 | 4 | 0 | 3 |
For details and further investigation, click here
