| Full name: SH3GL interacting endocytic adaptor 1 | Alias Symbol: DKFZp761D221 | ||
| Type: protein-coding gene | Cytoband: 1p31.3 | ||
| Entrez ID: 84251 | HGNC ID: HGNC:25412 | Ensembl Gene: ENSG00000118473 | OMIM ID: 611540 |
| Drug and gene relationship at DGIdb | |||
Expression of SGIP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SGIP1 | 84251 | 223672_at | -0.6901 | 0.5347 | |
| GSE26886 | SGIP1 | 84251 | 223672_at | 0.3564 | 0.1064 | |
| GSE45670 | SGIP1 | 84251 | 223672_at | -0.6529 | 0.0240 | |
| GSE53622 | SGIP1 | 84251 | 142928 | 0.1645 | 0.3519 | |
| GSE53624 | SGIP1 | 84251 | 117204 | 0.3869 | 0.0069 | |
| GSE63941 | SGIP1 | 84251 | 223672_at | -5.6616 | 0.0000 | |
| GSE77861 | SGIP1 | 84251 | 223672_at | 0.0851 | 0.4374 | |
| GSE97050 | SGIP1 | 84251 | A_23_P62881 | -0.2604 | 0.6788 | |
| SRP007169 | SGIP1 | 84251 | RNAseq | 5.2718 | 0.0000 | |
| SRP064894 | SGIP1 | 84251 | RNAseq | 0.8696 | 0.0025 | |
| SRP133303 | SGIP1 | 84251 | RNAseq | 0.9962 | 0.0061 | |
| SRP159526 | SGIP1 | 84251 | RNAseq | 0.4619 | 0.3316 | |
| SRP193095 | SGIP1 | 84251 | RNAseq | 1.8993 | 0.0000 | |
| SRP219564 | SGIP1 | 84251 | RNAseq | 0.6473 | 0.3244 | |
| TCGA | SGIP1 | 84251 | RNAseq | -0.5670 | 0.0020 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by SGIP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SGIP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SGIP1 | 84251 | 2 | 6 | 22 | |
| GSE20123 | SGIP1 | 84251 | 2 | 5 | 23 | |
| GSE43470 | SGIP1 | 84251 | 4 | 2 | 37 | |
| GSE46452 | SGIP1 | 84251 | 0 | 1 | 58 | |
| GSE47630 | SGIP1 | 84251 | 8 | 5 | 27 | |
| GSE54993 | SGIP1 | 84251 | 0 | 0 | 70 | |
| GSE54994 | SGIP1 | 84251 | 6 | 4 | 43 | |
| GSE60625 | SGIP1 | 84251 | 0 | 0 | 11 | |
| GSE74703 | SGIP1 | 84251 | 3 | 2 | 31 | |
| GSE74704 | SGIP1 | 84251 | 1 | 2 | 17 | |
| TCGA | SGIP1 | 84251 | 9 | 21 | 66 |
Total number of gains: 35; Total number of losses: 48; Total Number of normals: 405.
Somatic mutations of SGIP1:
Generating mutation plots.
Highly correlated genes for SGIP1:
Showing top 20/756 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SGIP1 | SST | 0.828594 | 3 | 0 | 3 |
| SGIP1 | PRKG1 | 0.787467 | 8 | 0 | 8 |
| SGIP1 | CNTN3 | 0.78712 | 3 | 0 | 3 |
| SGIP1 | ITGA1 | 0.785217 | 7 | 0 | 7 |
| SGIP1 | MGARP | 0.783885 | 3 | 0 | 3 |
| SGIP1 | DNM3OS | 0.769374 | 3 | 0 | 3 |
| SGIP1 | LAMA4 | 0.752952 | 8 | 0 | 8 |
| SGIP1 | HABP4 | 0.751279 | 5 | 0 | 5 |
| SGIP1 | FIBIN | 0.746591 | 5 | 0 | 5 |
| SGIP1 | SEMA3A | 0.745336 | 4 | 0 | 4 |
| SGIP1 | TRIM23 | 0.743911 | 3 | 0 | 3 |
| SGIP1 | GRIN3A | 0.743177 | 3 | 0 | 3 |
| SGIP1 | SESN1 | 0.741026 | 3 | 0 | 3 |
| SGIP1 | RASSF8 | 0.734465 | 5 | 0 | 5 |
| SGIP1 | BCL6 | 0.732911 | 3 | 0 | 3 |
| SGIP1 | PIP5K1C | 0.731872 | 3 | 0 | 3 |
| SGIP1 | FAM8A1 | 0.731098 | 3 | 0 | 3 |
| SGIP1 | KANSL3 | 0.727138 | 3 | 0 | 3 |
| SGIP1 | MCAM | 0.725216 | 6 | 0 | 5 |
| SGIP1 | IRAK3 | 0.725137 | 3 | 0 | 3 |
For details and further investigation, click here
