| Full name: protocadherin 7 | Alias Symbol: BH-Pcdh|PPP1R120 | ||
| Type: protein-coding gene | Cytoband: 4p15.1 | ||
| Entrez ID: 5099 | HGNC ID: HGNC:8659 | Ensembl Gene: ENSG00000169851 | OMIM ID: 602988 |
| Drug and gene relationship at DGIdb | |||
Expression of PCDH7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCDH7 | 5099 | 228640_at | -0.6106 | 0.6386 | |
| GSE20347 | PCDH7 | 5099 | 210273_at | -0.2322 | 0.2192 | |
| GSE23400 | PCDH7 | 5099 | 210273_at | -0.1700 | 0.0980 | |
| GSE26886 | PCDH7 | 5099 | 228640_at | 2.1364 | 0.0039 | |
| GSE29001 | PCDH7 | 5099 | 205534_at | 0.0206 | 0.9786 | |
| GSE38129 | PCDH7 | 5099 | 210273_at | -0.7888 | 0.0044 | |
| GSE45670 | PCDH7 | 5099 | 228640_at | -1.5126 | 0.0100 | |
| GSE53622 | PCDH7 | 5099 | 76847 | -0.1470 | 0.4430 | |
| GSE53624 | PCDH7 | 5099 | 76847 | -0.0479 | 0.7472 | |
| GSE63941 | PCDH7 | 5099 | 228640_at | -1.5927 | 0.2934 | |
| GSE77861 | PCDH7 | 5099 | 228640_at | -0.4369 | 0.6028 | |
| GSE97050 | PCDH7 | 5099 | A_33_P3349646 | -1.2406 | 0.0465 | |
| SRP007169 | PCDH7 | 5099 | RNAseq | 0.5812 | 0.2187 | |
| SRP008496 | PCDH7 | 5099 | RNAseq | 0.3761 | 0.2228 | |
| SRP064894 | PCDH7 | 5099 | RNAseq | 0.2886 | 0.3508 | |
| SRP133303 | PCDH7 | 5099 | RNAseq | -0.3588 | 0.2167 | |
| SRP193095 | PCDH7 | 5099 | RNAseq | 0.3444 | 0.1672 | |
| SRP219564 | PCDH7 | 5099 | RNAseq | -0.2266 | 0.7749 | |
| TCGA | PCDH7 | 5099 | RNAseq | -0.3835 | 0.0057 |
Upregulated datasets: 1; Downregulated datasets: 2.
Survival by PCDH7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCDH7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCDH7 | 5099 | 0 | 18 | 12 | |
| GSE20123 | PCDH7 | 5099 | 0 | 17 | 13 | |
| GSE43470 | PCDH7 | 5099 | 0 | 14 | 29 | |
| GSE46452 | PCDH7 | 5099 | 1 | 36 | 22 | |
| GSE47630 | PCDH7 | 5099 | 1 | 19 | 20 | |
| GSE54993 | PCDH7 | 5099 | 9 | 0 | 61 | |
| GSE54994 | PCDH7 | 5099 | 4 | 11 | 38 | |
| GSE60625 | PCDH7 | 5099 | 0 | 0 | 11 | |
| GSE74703 | PCDH7 | 5099 | 0 | 12 | 24 | |
| GSE74704 | PCDH7 | 5099 | 0 | 11 | 9 | |
| TCGA | PCDH7 | 5099 | 10 | 49 | 37 |
Total number of gains: 25; Total number of losses: 187; Total Number of normals: 276.
Somatic mutations of PCDH7:
Generating mutation plots.
Highly correlated genes for PCDH7:
Showing top 20/503 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCDH7 | IRF2BP2 | 0.801396 | 3 | 0 | 3 |
| PCDH7 | PLEKHB1 | 0.727985 | 4 | 0 | 4 |
| PCDH7 | SLC19A2 | 0.710301 | 3 | 0 | 3 |
| PCDH7 | EIF1B | 0.707478 | 4 | 0 | 3 |
| PCDH7 | GAS7 | 0.707249 | 3 | 0 | 3 |
| PCDH7 | TMEM150A | 0.701841 | 3 | 0 | 3 |
| PCDH7 | SLC25A23 | 0.688524 | 4 | 0 | 3 |
| PCDH7 | SBF2 | 0.688239 | 3 | 0 | 3 |
| PCDH7 | MAP4 | 0.686258 | 5 | 0 | 4 |
| PCDH7 | PDCD4 | 0.685939 | 3 | 0 | 3 |
| PCDH7 | CKB | 0.685811 | 5 | 0 | 4 |
| PCDH7 | PCNP | 0.684506 | 3 | 0 | 3 |
| PCDH7 | TSPAN2 | 0.682398 | 8 | 0 | 7 |
| PCDH7 | CPE | 0.682243 | 6 | 0 | 6 |
| PCDH7 | HIBADH | 0.679768 | 3 | 0 | 3 |
| PCDH7 | FOXF2 | 0.6762 | 6 | 0 | 5 |
| PCDH7 | IRAK1BP1 | 0.673274 | 4 | 0 | 4 |
| PCDH7 | CAMTA2 | 0.672163 | 3 | 0 | 3 |
| PCDH7 | FRS2 | 0.672153 | 3 | 0 | 3 |
| PCDH7 | PLEKHA3 | 0.670782 | 3 | 0 | 3 |
For details and further investigation, click here
