| Full name: Kruppel like factor 16 | Alias Symbol: NSLP2|BTEB4|DRRF | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 83855 | HGNC ID: HGNC:16857 | Ensembl Gene: ENSG00000129911 | OMIM ID: 606139 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of KLF16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLF16 | 83855 | 224111_x_at | 0.1489 | 0.6433 | |
| GSE26886 | KLF16 | 83855 | 224111_x_at | 0.1704 | 0.1857 | |
| GSE45670 | KLF16 | 83855 | 224111_x_at | 0.0881 | 0.4126 | |
| GSE53622 | KLF16 | 83855 | 63135 | 0.2278 | 0.0018 | |
| GSE53624 | KLF16 | 83855 | 70620 | 0.3011 | 0.0001 | |
| GSE63941 | KLF16 | 83855 | 224111_x_at | 0.6923 | 0.0002 | |
| GSE77861 | KLF16 | 83855 | 224111_x_at | 0.1739 | 0.4365 | |
| GSE97050 | KLF16 | 83855 | A_33_P3374957 | 0.1643 | 0.5200 | |
| SRP007169 | KLF16 | 83855 | RNAseq | -0.2450 | 0.5393 | |
| SRP008496 | KLF16 | 83855 | RNAseq | -0.4172 | 0.2065 | |
| SRP064894 | KLF16 | 83855 | RNAseq | 0.3120 | 0.2299 | |
| SRP133303 | KLF16 | 83855 | RNAseq | 0.2695 | 0.1923 | |
| SRP159526 | KLF16 | 83855 | RNAseq | -0.1396 | 0.7270 | |
| SRP193095 | KLF16 | 83855 | RNAseq | 0.3807 | 0.0183 | |
| SRP219564 | KLF16 | 83855 | RNAseq | 0.2235 | 0.5943 | |
| TCGA | KLF16 | 83855 | RNAseq | 0.1906 | 0.0004 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by KLF16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLF16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLF16 | 83855 | 4 | 6 | 20 | |
| GSE20123 | KLF16 | 83855 | 4 | 5 | 21 | |
| GSE43470 | KLF16 | 83855 | 1 | 10 | 32 | |
| GSE46452 | KLF16 | 83855 | 47 | 1 | 11 | |
| GSE47630 | KLF16 | 83855 | 5 | 7 | 28 | |
| GSE54993 | KLF16 | 83855 | 16 | 3 | 51 | |
| GSE54994 | KLF16 | 83855 | 8 | 15 | 30 | |
| GSE60625 | KLF16 | 83855 | 9 | 0 | 2 | |
| GSE74703 | KLF16 | 83855 | 1 | 7 | 28 | |
| GSE74704 | KLF16 | 83855 | 3 | 3 | 14 | |
| TCGA | KLF16 | 83855 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 82; Total Number of normals: 302.
Somatic mutations of KLF16:
Generating mutation plots.
Highly correlated genes for KLF16:
Showing top 20/536 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLF16 | COPE | 0.804941 | 3 | 0 | 3 |
| KLF16 | MRPL38 | 0.79329 | 3 | 0 | 3 |
| KLF16 | CELA3A | 0.779945 | 3 | 0 | 3 |
| KLF16 | SLC26A5 | 0.774739 | 3 | 0 | 3 |
| KLF16 | ALG11 | 0.756856 | 3 | 0 | 3 |
| KLF16 | KRTAP12-2 | 0.750178 | 3 | 0 | 3 |
| KLF16 | SPEG | 0.74811 | 3 | 0 | 3 |
| KLF16 | OR1L6 | 0.744193 | 3 | 0 | 3 |
| KLF16 | SLC36A4 | 0.744047 | 3 | 0 | 3 |
| KLF16 | TRMT2B | 0.737251 | 3 | 0 | 3 |
| KLF16 | MAPRE3 | 0.736753 | 5 | 0 | 5 |
| KLF16 | OR2AT4 | 0.732732 | 3 | 0 | 3 |
| KLF16 | CCDC154 | 0.732304 | 6 | 0 | 5 |
| KLF16 | RIT2 | 0.732052 | 3 | 0 | 3 |
| KLF16 | CCIN | 0.728828 | 4 | 0 | 4 |
| KLF16 | IGF2-AS | 0.721548 | 3 | 0 | 3 |
| KLF16 | KRT81 | 0.720934 | 4 | 0 | 4 |
| KLF16 | EPN1 | 0.720579 | 6 | 0 | 6 |
| KLF16 | DCTN1 | 0.713874 | 3 | 0 | 3 |
| KLF16 | OR2T12 | 0.711608 | 3 | 0 | 3 |
For details and further investigation, click here
